Resumes & CV records
Resumes
Nathalie Toussaint
Nathalie Toussaint
Work:
Alm
Nathalie Y Toussaint, 44Massapequa Park, NY
Nathalie Toussaint Phones & Addresses
Massapequa Park, NY
South Danby, NY
49 Constitution Way, South River, NJ 08882 732-3536169
7123 Heather Dr, Princeton Junction, NJ 08550 609-3785680
West Windsor, NJ
North Brunswick, NJ
Gainesville, FL
Buffalo, NY
Brooklyn, NY
Middlesex, NJ
N Brunswick, NJ
49 Constitution Way, South River, NJ 08882
Work
Position:
Professional/Technical
Education
Degree:
Associate degree or higher
Mentions for Nathalie Y Toussaint
Alm
Publications & IP owners
Us Patents
Compounds For Reducing The Viscosity Of Biological Formulations
US Patent:
2020020, Jul 2, 2020
Filed:
Aug 31, 2018
Appl. No.:
16/644107
Inventors:
- Rahway NJ, US
Nathalie Y. Toussaint - South River NJ, US
Dong Xiao - Warren NJ, US
Petr Vachal - Summit NJ, US
Ramesh S. Kashi - Warren NJ, US
Annette Bak - Partille, SE
Nathalie Y. Toussaint - South River NJ, US
Dong Xiao - Warren NJ, US
Petr Vachal - Summit NJ, US
Ramesh S. Kashi - Warren NJ, US
Annette Bak - Partille, SE
Assignee:
Merck Sharp & Dohme Corp. - Rahway NJ
International Classification:
A61K 47/22
C07K 16/28
A61K 47/26
C07D 233/64
C07C 279/14
C07C 235/12
C07C 229/36
A61K 47/18
C07K 16/28
A61K 47/26
C07D 233/64
C07C 279/14
C07C 235/12
C07C 229/36
A61K 47/18
Abstract:
The present invention relates to pegylated amino acid compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein X, R, R, R, Rand n are as defined herein. The present invention also relates to compositions which comprise a pegylated amino acid compound of the invention or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, in combination with a high concentration of an active biological ingredient (ABI). In embodiments of the invention, the ABI is an anti-PD-1 antibody or antigen binding fragment thereof that specifically binds human programmed death receptor 1 (PD-1). The invention further relates to methods for lowering the viscosity of an aqueous solution of a pharmaceutical composition comprising adding a compound of the invention to the solution. The invention also provides methods for treating a pathological disease or condition, such as cancer, by administering to a subject in need of such treatment a therapeutically effective amount of a pharmaceutical composition of the invention.
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