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Norman L Greenberg, 823403 Mont Blanc, San Antonio, TX 78258

Norman Greenberg Phones & Addresses

San Antonio, TX   

Crystal Beach, TX   

4369 Faculty Ln, Houston, TX 77004   

Austin, TX   

2230 6Th St, Port Neches, TX 77651    409-7242281   

Nederland, TX   

Work

Company: Pfizer Jan 2009 Position: Senior director

Education

School / High School: Baylor College of Medicine- Houston, TX Jan 1988 Specialities: PostDoctoral Fellow in Endocrinology, Molecular Biology, Oncology

Skills

Molecular Biology DNA / RNA isolation • purification • recombinant techniques • vector construction purification and analytics • Northern / Southern / Western (and related) blotting • DNA sequencing • PCR • RT-PCR • Real-time PCR • mutagenesis • colony hybridization • sequence analysis • reporter gene assays • high throughput screening Immunology Enzyme linked immunosorbent assays • radioimmunoassay • immunoblotting • immunoprecipitation • monoclonal and polyclonal antisera production • adoptive transfer technology • stem cell isolation and purification Cell Biology Mammalian cell culture • transfection • protein expression in bacteria and mammalian cells • stable and transient transfection • immunofluorescence • immunohistochemistry • histology • FACS analysis Protein Biochemistry Affinity chromatography • HPLC • FPLC • binding assays • electrophoresis • enzyme assays • signal transduction assays • Lowry • BCA protein assays In Vivo Generation and analysis of genetically engineered mouse model systems • vector construction • homologous recombination • transgenesis • histology • pathology • non-invasive image analysis including microcomputed tomography • magnetic resonance imaging • luminescent and fluorescent imaging • positron emission tomography • radiolabelled reporters • general animal husbandry PO/IP dosing • necropsy • anesthesia administration • tumor xenografts • ascites drug formulation • PK/PD • biomarker development • nanomolecules.

Mentions for Norman L Greenberg

Norman Greenberg resumes & CV records

Resumes

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Norman Michael Greenberg

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Norman Greenberg

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Norman Greenberg

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Norman Greenberg

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Vice President, Oncology Research And Development At Medimmune

Position:
Vice President Research and Development at MedImmune
Location:
Gaithersburg, Maryland
Industry:
Biotechnology
Work:
MedImmune - Gaithersburg, Maryland since Aug 2011
Vice President Research and Development
Pfizer Jun 2009 - Jul 2011
Senior Director
University of Washington Jan 2005 - 2009
Professor of Pharmacology
Fred Hutchinson Cancer Research Center Jan 2004 - Dec 2009
Full Member - Professor
Baylor College of Medicine Sep 1998 - Dec 2003
Associate Professor
Baylor College of Medicine Sep 1992 - Aug 1998
Assistant Professor
Education:
Baylor College of Medicine 1988 - 1992
Postdoctoral, Molecular Biology / Oncology / Endocrinology
The University of British Columbia 1982 - 1988
PhD, Molecular Biology / Microbiology
University of Toronto 1978 - 1982
BSc (Hons), Microbiology and Immunology
Norman Greenberg Photo 39

Norman Greenberg

Work:
Pfizer Jan 2009 to Present
Senior Director
Fred Hutchinson Cancer Center - Seattle, WA Jan 2004 to Dec 2009
Professor and Full Member, Clinical Research Divivsion
Baylor College of Medicine - Houston, TX Sep 1998 to Dec 2003
Associated Professor (Tenured), Molecular/Cellular Biology and Urology
Baylor College of Medicine - Houston, TX Sep 1994 to Aug 1998
Assistant Professor (Tenure Track), Molecular/Cellular Biology and Urology
Education:
Baylor College of Medicine - Houston, TX Jan 1988 to Jan 1994
PostDoctoral Fellow in Endocrinology, Molecular Biology, Oncology
University of British Columbia - Vancouver, BC Jan 1982 to Jan 1988
PhD in Molecular Biology and Gene Regulation
University of Toronto - Toronto, ON Jan 1978 to Jan 1982
BSc in Microbiology and Immunology
Skills:
Molecular Biology DNA / RNA isolation, purification, recombinant techniques, vector construction purification and analytics, Northern / Southern / Western (and related) blotting, DNA sequencing, PCR, RT-PCR, Real-time PCR, mutagenesis, colony hybridization, sequence analysis, reporter gene assays, high throughput screening Immunology Enzyme linked immunosorbent assays, radioimmunoassay, immunoblotting, immunoprecipitation, monoclonal and polyclonal antisera production, adoptive transfer technology, stem cell isolation and purification Cell Biology Mammalian cell culture, transfection, protein expression in bacteria and mammalian cells, stable and transient transfection, immunofluorescence, immunohistochemistry, histology, FACS analysis Protein Biochemistry Affinity chromatography, HPLC, FPLC, binding assays, electrophoresis, enzyme assays, signal transduction assays, Lowry, BCA protein assays In Vivo Generation and analysis of genetically engineered mouse model systems, vector construction, homologous recombination, transgenesis, histology, pathology, non-invasive image analysis including microcomputed tomography, magnetic resonance imaging, luminescent and fluorescent imaging, positron emission tomography, radiolabelled reporters, general animal husbandry PO/IP dosing, necropsy, anesthesia administration, tumor xenografts,, ascites drug formulation, PK/PD, biomarker development, nanomolecules.

Publications & IP owners

Us Patents

Transgenic Mouse Model For Prostate Cancer

US Patent:
5907078, May 25, 1999
Filed:
Mar 31, 1995
Appl. No.:
8/414335
Inventors:
Norman M. Greenberg - Houston TX
Robert J. Matusik - Winnipeg, Manitoba, CA
Jeffrey M. Rosen - Houston TX
International Classification:
C12N 1500
US Classification:
800 2
Abstract:
Several lines of transgenic mice have been generated using the prostate-specific rat probasin (PB) gene promoter to drive expression of the SV40 T antigen (Tag) coding region. Mice expressing high levels of the transgene specifically display progressive forms of prostatic cancer that histologically resemble human prostate cancer ranging from mild prostatic intraepithelial neoplasia (PIN) to large multinodular malignant adenocarcinoma with metastasis. Adenocarcinomas of the prostate have been detected as early as 10 weeks of age with extracapsular extension (ECE) and seminal vesicle invasion (SVI). Immunohistochemical analysis of tumor tissue has demonstrated that dorsolateral prostate-specific secretory proteins were confined to well differentiated ductal epithelial cells adjacent to, or within the poorly differentiated tumor mass. Prostate tumors in the mice also display elevated levels of nuclear p53, and a decreased heterogenous pattern of androgen receptor (AR) expression as observed in advanced human prostate cancer. The establishment of breeding lines of transgenic mice that reproducibly develop prostate cancer with metastasis provides a unique animal model system to study the molecular basis of transformation of normal prostatic cells and the factors influencing the progression to metastatic prostate cancer.

Isbn (Books And Publications)

The Man With A Steel Guitar: A Portrait Of Ambition, Desperation, And Crime

Author:
Norman Greenberg
ISBN #:
0874511755

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