Pankaj Singh, 48Pompano Beach, FL

D644327, Aug 30, 2011

Sep 2, 2010

29/369101

Pankaj P. Singh - Brookville NY, US

2402

D24146, D15139, D24152

2012004, Feb 23, 2012

Aug 20, 2010

12/860830

PANKAJ PAL SINGH - Brookville NY, US

A61C 3/02

433 76

A guided pin system (GPS) trephine drill may be used for the placement of a dental implant while simultaneously collecting a substantial volume of autogenous bone that otherwise would have been discarded off during the current method of sequentially enlarging diameter spade drills. A method for preparing a dental implant site may include drilling the site with a pilot drill to a depth about 1 mm deeper than the intended length, in the axial direction, of the implant. The GPS trephine drill may be advanced along a straight axial path created by the pilot drill to a final depth determined by the bottoming out of a protruding pin on the trephine drill.

2012018, Jul 26, 2012

Jan 26, 2011

13/014646

Pankaj P. Singh - Brookville NY, US

A61F 5/56
A61C 9/00

128848, 433214

Methods and apparatus for treating snoring and sleep apnea may include an oral appliance based on an extensive, three-dimensional radiological and clinical examination. The oral appliance may position the patient's lower jaw to a position that may prevent or eliminate sleep apnea. Several parameters, often over 40 parameters, may be examined to determine the proper placement and orientation of the jaw, via the oral appliance. The oral appliance may have a soft insert on the inside for cushioning the patient's teeth while the outside of the oral appliance may be hard, so as to maintain airflow through the oral appliance. The oral appliance may be a “full coverage” piece, fitting over 70 percent, typically over 80 percent, of the patient's teeth.

2012020, Aug 16, 2012

Feb 10, 2011

13/025028

Pankaj P. Singh - Brookville NY, US

A61C 8/00

433173

A dental implant has an implant body that releases drug(s) to the patient. In some embodiments, the dental implant body may be coated with drugs, such as anti-inflammatory drugs and/or anti-infective/antibiotic drugs. The drugs may be formulated in a time released or extended released formulation so as to deliver the drugs over an extended period of time. The drugs may be formulated to not only slowly deliver the drug substance, but to also provide a drug substance that may be delivered locally, with minimal systemic drug perfusion. The drug alluding implants of the present invention may help reduce or eliminated complications related to dental implant surgery.

2020038, Dec 10, 2020

Nov 30, 2018

16/762326

- Albany NY, US
- Austin TX, US
- Atlanta GA, US
- Seattle WA, US
Rebecca BATISTE - Stony Brook NY, US
Le HOU - Stony Brook NY, US
Vu NGUYEN - Stony Brook NY, US
Dimitrios SAMARAS - Rocky Point NY, US
Arvind RAO - Houston TX, US
John VAN ARNAM - Houston TX, US
Pankaj SINGH - Houston TX, US
Alexander LAZAR - Houston TX, US
Ashish SHARMA - Atlanta GA, US
Ilya SHMULEVICH - Seattle WA, US
Vesteinn THORSSON - Seattle WA, US

G06T 7/00
G06K 9/32
G06T 9/00
G06K 9/62
G06T 7/11

A system associated with quantifying a density level of tumor-infiltrating lymphocytes, based on prediction of reconstructed TIL information associated with tumoral tissue image data during pathology analysis of the tissue image data is disclosed. The system receives digitized diagnostic and stained whole-slide image data related to tissue of a particular type of tumoral data. Defined are regions of interest that represents a portion of, or a full image of the whole-slide image data. The image data is encoded into segmented data portions based on convolutional autoencoding of objects associated with the collection of image data. The density of tumor-infiltrating lymphocytes is determined of bounded segmented data portions for respective classification of the regions of interest. A classification label is assigned to the regions of interest. It is determined whether an assigned classification label is above a pre-determined threshold probability value of lymphocyte infiltrated. The threshold probability value is adjusted in order to re-assign the classification label to the regions of interest based on a varied sensitivity level of density of lymphocyte infiltrated. A trained classification model is generated based on the re-assigned classification labels to the regions of interest associated with segmented data portions using the adjusted threshold probability value. An unlabeled image data set is received to iteratively classify the segmented data portions based on a lymphocyte density level associated with portions of the unlabeled image data set, using the trained classification model. Tumor-infiltrating lymphocyte representations are generated based on prediction of TIL information associated with classified segmented data portions. A refined TIL representation based on prediction of the TIL representations is generated using the adjusted threshold probability value associated with the classified segmented data portions. A corresponding method and computer-readable device are also disclosed.