Paul Mangan resumes & CV records
Resumes
Paul Mangan
Location:
United States
Paul Mangan
Location:
United States
Paul R Mangan, 784980 Applebutter Rd, Pipersville, PA 18947
Paul Mangan Phones & Addresses
Pipersville, PA
Doylestown, PA
3703 Baring St, Philadelphia, PA 19104 215-2223546
1035 Beacon Cir, Birmingham, AL 35209 205-9438492
1839 Arboretum Cir, Vestavia Hills, AL 35216 205-8238892
2413 Rime Vlg, Hoover, AL 35216 205-9883000
Vestavia, AL
Silver Spring, MD
Buck, PA
Mentions for Paul R Mangan
Publications & IP owners
Us Patents
Pathway For Th-17 Cell Development And Methods Utilizing Same
US Patent:
2010020, Aug 12, 2010
Filed:
Oct 16, 2009
Appl. No.:
12/580926
Inventors:
Casey T. Weaver - Birmingham AL, US
Paul R. Mangan - Doylestown PA, US
Laurie E. Harrington - Birmingham AL, US
Paul R. Mangan - Doylestown PA, US
Laurie E. Harrington - Birmingham AL, US
Assignee:
THE UAB RESEARCH FOUNDATION - Birmingham AL
International Classification:
A61K 38/20
A61K 39/395
A61K 38/16
A61K 31/7088
A61K 38/21
A61P 37/04
A61K 39/395
A61K 38/16
A61K 31/7088
A61K 38/21
A61P 37/04
US Classification:
424 852, 4241581, 514 12, 514 44 R, 424 855, 424 857
Abstract:
The present disclosure demonstrates for the first time that Th-17 cells are the product of a distinct CD4 T cell lineage with unique developmental and functional characteristics. The developmental signals required for Th-17 commitment and development are also described. As a result, the teachings of the present disclosure provide a basis for understanding the developmental pathway of Th-17 cells and offer novel avenues to modulate (stimulate or inhibit) this developmental program and offer new methods for the treatment and prevention of disease states and conditions related to aberrant activity of Th-17 cells.
Pathway For Th-17 Cell Development And Methods Utilizing Same
US Patent:
8414897, Apr 9, 2013
Filed:
Oct 2, 2007
Appl. No.:
11/866380
Inventors:
Casey T. Weaver - Birmingham AL, US
Paul R. Mangan - Doylestown PA, US
Laurie E. Harrington - Birmingham AL, US
Paul R. Mangan - Doylestown PA, US
Laurie E. Harrington - Birmingham AL, US
Assignee:
The UAB Research Foundation - Birmingham AL
International Classification:
A61K 39/395
US Classification:
4241581, 4241301
Abstract:
The present disclosure demonstrates for the first time that Th-17 cells are the product of a distinct CD4 T cell lineage with unique developmental and functional characteristics. The developmental signals required for Th-17 commitment and development are also described. As a result, the teachings of the present disclosure provide a basis for understanding the developmental pathway of Th-17 cells and offer novel avenues to modulate (stimulate or inhibit) this developmental program and offer new methods for the treatment and prevention of disease states and conditions related to aberrant activity of Th-17 cells.
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