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Paul S Sweetnam, 925835 Marina Dr, Sebastian, FL 32958

Known as:
Paul Sweetnan Ann Sweetnam Paul Sweetman
Related to:
Anne D Sweetnam 80

Paul Sweetnam Phones & Addresses

5835 Marina Dr, Sebastian, FL 32958    772-9188845   

5835 Marina Dr #5, Sebastian, FL 32958    772-9188845   

Westport, MA   

Vero Beach, FL   

760 Plains Rd, Silver Lake, NH 03875    603-3674760   

256 Marginal St, East Boston, MA 02128    617-5671230   

Boston, MA   

256 Marginal St STE 2A, Boston, MA 02128   

Work

Position: Machine Operators, Assemblers, and Inspectors Occupations
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Career records & work history

License Records

Paul S Sweetnam

Address:
Westport, MA 02790
Licenses:
License #: 122233 - Expired
Issued Date: Feb 1, 1980
Expiration Date: Aug 22, 2006
Type: Broker

Publications & IP owners

Us Patents

Method Of Monitoring Haptotaxis

US Patent:
6818403, Nov 16, 2004
Filed:
Mar 15, 2002
Appl. No.:
10/097304
Inventors:
Gregory L. Kirk - Winchester MA
Matthew Brown - Brighton MA
Emanuele Ostuni - Watertown MA
Enoch Kim - Boston MA
Bernardo D. Aumond - Somerville MA
Olivier Schueller - Somerville MA
Paul Sweetnam - Marblehead MA
Brian Benoit - Westborough MA
Assignee:
Surface Logix, Inc. - Brighton MA
International Classification:
C12Q 168
US Classification:
435 6, 435 29, 435177
Abstract:
The present invention discloses a method of monitoring haptotaxis comprising: providing a device for monitoring haptotaxis having a housing defining a chamber. The chamber includes: a first well region including at least one first well, the first well region configured to receive a test agent therein and further including biomolecules immobilized therein; a second well region including at least one second well, the second well region configured to receive a sample comprising cells therein and further being horizontally offset with respect to the first well region in a test orientation of the device; and a channel region with biomolecules immobilized therein and including at least one channel connecting the first well region and the second well region with one another. The method also includes forming a surface concentration gradient along a longitudinal axis of the chamber by decreasing the concentration of biomolecules from the at least one first well to the at least one second well; placing a first sample comprising cells in the at least one second well; and monitoring haptotaxis of the cells.

Cell Motility And Chemotaxis Test Device And Methods Of Using Same

US Patent:
6921660, Jul 26, 2005
Filed:
Mar 15, 2002
Appl. No.:
10/097351
Inventors:
Gregory L. Kirk - Winchester MA, US
Matthew Brown - Brighton MA, US
Emanuele Ostuni - Watertown MA, US
Enoch Kim - Boston MA, US
Bernardo D. Aumond - Somerville MA, US
Olivier Schueller - Arlington MA, US
Paul Sweetnam - Marblehead MA, US
Brian Benoit - Westborough MA, US
Assignee:
Surface Logix, Inc. - Brighton MA
International Classification:
C12M001/34
US Classification:
4352872, 4352885, 435809, 422102
Abstract:
The present invention discloses a device for monitoring chemotaxis or chemoinvasion including a housing comprising: a support member and a top member, the top member mounted to the support member by being placed in substantially fluid-tight conformal contact with the support member. The support member and the top member are configured such that they together define a discrete chamber adapted to allow a monitoring of chemotaxis or chemoinvasion therein. The discrete chamber includes a first well region including at least one first well, the at least one first well configured to received a test agent therein; a second well region including at least one second well, the at least one second well configured to receive a sample comprising cells therein; and a channel region including at least one channel connecting the first well region and the second well region with one another. The second well region is preferably horizontally offset with respect to the first well region in a test orientation of the device.

Image Processing Method For Use In Analyzing Data Of A Chemotaxis Or Haptotaxis Assay

US Patent:
7123764, Oct 17, 2006
Filed:
Mar 15, 2002
Appl. No.:
10/097302
Inventors:
Gregory L. Kirk - Winchester MA, US
Matthew Brown - Brighton MA, US
Emanuele Ostuni - Watertown MA, US
Enoch Kim - Boston MA, US
Bernardo D. Aumond - Somerville MA, US
Olivier Schueller - Somerville MA, US
Paul Sweetnam - Marblehead MA, US
Brian Benoit - Westborough MA, US
Assignee:
Surface Logix Inc. - Brighton MA
International Classification:
G06K 9/00
US Classification:
382133, 382274, 435 4
Abstract:
An image processing method for use in analyzing image data of a cellular migration assay. The method includes defining a major axis within the image data that is perpendicular to an orientation of channels in the image data, determining an aggregate light intensity within the image data along the major axis, and identifying locations of channels within the image data from the projection.

Test Device And Method Of Making Same

US Patent:
7166459, Jan 23, 2007
Filed:
Mar 15, 2002
Appl. No.:
10/097329
Inventors:
Gregory Kirk - Winchester MA, US
Matthew Brown - Watertown MA, US
Emanuele Ostuni - Cambridge MA, US
Enoch Kim - Boston MA, US
Bernardo Aumond - Cambridge MA, US
Olivier Schueller - Somerville MA, US
Paul Sweetnam - Marblehead MA, US
Brian Benoit - Westborough MA, US
Assignee:
Surface Logix, Inc. - Brighton MA
International Classification:
C12M 1/34
US Classification:
4352884, 4352885, 4352886, 435810, 422101
Abstract:
The present invention discloses a test device including a support member; a top member mounted to the support member, wherein in the support member and the top member are configured such that they together define a discrete chamber. The discrete chamber includes a first well region including at least one first well; a second well region including at least one second well; and a channel region including at least one channel connecting the first well region and the second well region with one another. The second region is preferably horizontally offset with respect to the first well region in a test orientation of the device.

Device For Monitoring Haptotaxis

US Patent:
7364899, Apr 29, 2008
Filed:
Mar 15, 2002
Appl. No.:
10/097306
Inventors:
Gregory L. Kirk - Winchester MA, US
Matthew Brown - Brighton MA, US
Emanuele Ostuni - Watertown MA, US
Enoch Kim - Boston MA, US
Bernardo D. Aumond - Somerville MA, US
Olivier Schueller - Somerville MA, US
Paul Sweetnam - Marblehead MA, US
Brian Benoit - Westborough MA, US
Assignee:
Surface Logix Inc. - Brighton MA
International Classification:
C12M 1/34
C12M 3/00
US Classification:
4352885, 4352884, 435 33, 435 29, 435177, 4352886
Abstract:
The present invention discloses a device for monitoring haptotaxis including a housing defining a chamber. The chamber comprises: a first well region including at least one first well, the first well configured to receive a test agent therein and further including biomolecules immobilized therein; a second well region including at least one second well, the second well region configured to receive a sample comprising cells therein and further being horizontally offset with respect to the first well region in a test orientation of the device; and a channel region including at a least one channel connecting the first well region and the second well region with one another, the channel region further including biomolecules immobilized therein.

Biological Assays Using Gradients Formed In Microfluidic Systems

US Patent:
7374906, May 20, 2008
Filed:
Oct 21, 2003
Appl. No.:
10/688905
Inventors:
Gregory L. Kirk - Winchester MA, US
Emanuele Ostuni - Watertown MA, US
Enoch Kim - Boston MA, US
Olivier Schueller - Arlington MA, US
Paul Sweetnam - Marblehead MA, US
Assignee:
Surface Logix, Inc. - Brighton MA
International Classification:
C12Q 1/04
C12Q 1/20
C12M 3/00
C12M 1/36
C12M 1/34
US Classification:
435 34, 435 33, 4352883, 4352884, 4352885, 4352878, 4352879, 4353051, 4353053
Abstract:
The present invention discloses a device for monitoring chemotaxis or chemoinvasion. The present invention further provides a flexible assay system and numerous assays that can be used to test biological interactions and systems. Laminar flow gradients are employed that mimic gradient situations present in vivo.

Device And Method For Monitoring Leukocyte Migration

US Patent:
7419823, Sep 2, 2008
Filed:
Oct 21, 2003
Appl. No.:
10/688904
Inventors:
Gregory L. Kirk - Winchester MA, US
Emanuele Ostuni - Watertown MA, US
Enoch Kim - Boston MA, US
Olivier Schueller - Arlington MA, US
Paul Sweetnam - Marblehead MA, US
Assignee:
Surface Logix, Inc. - Brighton MA
International Classification:
C12M 1/36
C12M 1/38
C12M 3/00
C12M 1/34
C12M 1/22
US Classification:
4352885, 4352884, 4352883, 4352878, 4353053, 4353051, 4352789
Abstract:
A device for monitoring leukocyte migration is provided. The invention also provides a method of using the device to monitor leukocyte migration in the presence of physiological shear flow and therefore simulate physiological conditions of a blood vessel in vivo. The invention further provides a method of using the device to high-throughput screen a plurality of test agents. The present invention further provides a flexible assay system and numerous assays that can be used to test biological interactions and systems. Laminar flow gradients are employed that mimic gradient situations present in vivo.

Pharmacokinetically Improved Compounds

US Patent:
8357693, Jan 22, 2013
Filed:
Mar 27, 2006
Appl. No.:
11/887218
Inventors:
Alessandra Bartolozzi - Somerville MA, US
Stewart Campbell - Framingham MA, US
Hope Foudoulakis - Framingham MA, US
Brian Kirk - Sudbury MA, US
Siya Ram - Winchester MA, US
Paul Sweetnam - Marblehead MA, US
Assignee:
Surface Logix, Inc. - Brighton MA
International Classification:
A01N 43/54
A61K 31/517
US Classification:
51426623, 544284
Abstract:
The present invention relates to inhibitors of ROCK1 and ROCK2 and methods of modulating the pharmacokinetic and/or pharmacodynamic properties of such compounds. Also provided are methods of inhibiting ROCK1 and or ROCK2 that are useful for the treatment of disease.

Possible Relatives

Dale A Sweetnam  Edward M Sweetnam  George H Sweetnam  Mark E Sweetnam  Robert J Sweetnam  Paul M Johnson  Paul Stamps  Paul B Stanaway  Paul Stanczyk  Paul L Standefer 

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