Peter Dorff resumes & CV records
Resumes
Peter N Dorff, 482950 Vassar Dr, Boulder, CO 80305
Peter Dorff Phones & Addresses
Boulder, CO
5311 Tuscarawas Rd, Bethesda, MD 20816
Swarthmore, PA
Secane, PA
Wilmington, DE
Glen Mills, PA
San Pablo, CA
Oakland, CA
516 Walnut Ln, Swarthmore, PA 19081
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Publications & IP owners
Us Patents
Ligands
US Patent:
7982038, Jul 19, 2011
Filed:
Sep 24, 2004
Appl. No.:
10/573133
Inventors:
Peter Dorff - Wilmington DE, US
John Gordon - Wilmington DE, US
John Richard Heys - Wilmington DE, US
Richard A Keith - Wilmington DE, US
Dennis J McCarthy - Wilmington DE, US
Mark A Smith - Wilmington DE, US
Eifion Phillips - Bothwyn PA, US
John Gordon - Wilmington DE, US
John Richard Heys - Wilmington DE, US
Richard A Keith - Wilmington DE, US
Dennis J McCarthy - Wilmington DE, US
Mark A Smith - Wilmington DE, US
Eifion Phillips - Bothwyn PA, US
Assignee:
AstraZeneca AB
International Classification:
C07D 413/04
A61K 31/44
A61K 31/44
US Classification:
546 18, 514278, 514281
Abstract:
A radioactive compound having the formula:and pharmaceutically-acceptable salts thereof, wherein Rand Ar are as defined in the specification, enantiomers, in vivo-hydrolysable precursors, pharmaceutical compositions and formulations containing them, methods of using them to treat diseases and conditions either alone or in combination with other therapeutically-active compounds or substances, processes and intermediates used to prepare them and uses of them for diagnostic and analytic purposes.
Imaging Agents And Methods Of Imaging Alpha7-Nicotinic Cholinergic Receptor
US Patent:
2005012, Jun 16, 2005
Filed:
Jun 24, 2004
Appl. No.:
10/877813
Inventors:
Martin Pomper - Baltimore MD, US
John Musachio - Baltimore MD, US
Hong Fan - Lutherville Timonium MD, US
Robert Dannals - Sparks MD, US
Catherine Foss - Baltimore MD, US
Eifion Phillips - Wilmington DE, US
John Gordon - Wilmington DE, US
Dennis McCarthy - Wilmington DE, US
Richard Keith - Wilmington DE, US
Mark Smith - Wilmington DE, US
Richard Heys - Wilmington DE, US
Peter Dorff - Wilmington DE, US
John Musachio - Baltimore MD, US
Hong Fan - Lutherville Timonium MD, US
Robert Dannals - Sparks MD, US
Catherine Foss - Baltimore MD, US
Eifion Phillips - Wilmington DE, US
John Gordon - Wilmington DE, US
Dennis McCarthy - Wilmington DE, US
Richard Keith - Wilmington DE, US
Mark Smith - Wilmington DE, US
Richard Heys - Wilmington DE, US
Peter Dorff - Wilmington DE, US
International Classification:
A61K051/00
A61K031/4747
C07D491/14
C07F005/00
A61K031/4747
C07D491/14
C07F005/00
US Classification:
424001110, 514278000, 534011000, 546018000
Abstract:
The present invention relates to radiolabelled compounds particularly 1-azabicyclo[2.2.2]octane compounds (i.e., quinuclidine compounds) which are labeled with one or more radioisotopes and which are suitable for imaging or therapeutic treatment of tissues, organs, or tumors which express the a7-nicotinic cholinergic receptor. In another embodiment, the invention relates to methods of imaging tissues, organs, or tumors using radiolabeled compounds of the invention, particularly tissues, organs, or tumors which express a7-nicotinic cholinergic receptor to which the compounds of the invention have an affinity.
Methods For Purifying Radiolabelled Compounds
US Patent:
2009000, Jan 1, 2009
Filed:
Feb 25, 2008
Appl. No.:
12/037011
Inventors:
John F. Valliant - Ancaster, CA
Peter Dorff - Glen Mills PA, US
Raman Chirakal - Brantford, CA
Peter Dorff - Glen Mills PA, US
Raman Chirakal - Brantford, CA
International Classification:
C07F 7/22
US Classification:
534 10
Abstract:
One aspect of the present invention relates to a method of purifying radiolabelled compounds comprising a) loading onto a fluorous polymer a radiolabelled compound precursor comprising a fluoroalkyl tin moiety; b) reacting the radiolabelled compound precursor with a radiolabel delivering compound to give a radiolabelled compound, wherein the fluoroalkyl tin moiety is replaced by a radiolabel; and c) eluting the radiolabelled compound from the fluorous polymer.
Imaging Agents And Methods Of Imaging Alpha7-Nicotinic Cholinergic Receptor
US Patent:
2010003, Feb 11, 2010
Filed:
Jan 26, 2009
Appl. No.:
12/321951
Inventors:
Martin G. Pomper - Baltimore MD, US
John L. Musachio - Baltimore MD, US
Hong Fan - Lutherville Timonium MD, US
Robert F. Dannals - Sparks MD, US
Catherine Foss - Baltimore MD, US
Eifion Phillips - Wilmington DE, US
John Gordon - Wilmington DE, US
Dennis McCarthy - Wilmington DE, US
Richard Keith - Wilmington DE, US
Mark Smith - Wilmington DE, US
Richard Heys - Wilmington DE, US
Peter N. Dorff - Wilmington DE, US
John L. Musachio - Baltimore MD, US
Hong Fan - Lutherville Timonium MD, US
Robert F. Dannals - Sparks MD, US
Catherine Foss - Baltimore MD, US
Eifion Phillips - Wilmington DE, US
John Gordon - Wilmington DE, US
Dennis McCarthy - Wilmington DE, US
Richard Keith - Wilmington DE, US
Mark Smith - Wilmington DE, US
Richard Heys - Wilmington DE, US
Peter N. Dorff - Wilmington DE, US
Assignee:
The Johns Hopkins University - Baltimore MD
International Classification:
C07D 453/02
C07D 453/00
A61K 51/04
G01N 33/53
C07D 453/00
A61K 51/04
G01N 33/53
US Classification:
424 189, 546133, 546 83, 424 181, 424 185, 435 72
Abstract:
The present invention relates to radiolabelled compounds particularly 1-azabicyclo[2.2.2]octane compounds (i.e., quinuclidine compounds) which are labeled with one or more radioisotopes and which are suitable for imaging or therapeutic treatment of tissues, organs, or tumors which express the α7-nicotinic cholinergic receptor. In another embodiment, the invention relates to methods of imaging tissues, organs, or tumors using radiolabeled compounds of the invention, particularly tissues, organs, or tumors which express α7-nicotinic cholinergic receptor to which the compounds of the invention have an affinity.
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