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Peter A Torzilli, 78355 Old Sib Rd, Ridgefield, CT 06877

Peter Torzilli Phones & Addresses

355 Old Sib Rd, Ridgefield, CT 06877    203-4380063    203-4384272   

336 Barrack Hill Rd, Ridgefield, CT 06877    203-4384272   

Stamford, CT   

Mentions for Peter A Torzilli

Publications & IP owners

Us Patents

Glycation Cross-Link Breakers To Increase Resistance To Enzymatic Degradation

US Patent:
2013031, Nov 21, 2013
Filed:
May 16, 2013
Appl. No.:
13/895527
Inventors:
Peter A. Torzilli - Ridgefield CT, US
International Classification:
C07K 14/78
US Classification:
530356, 2524002
Abstract:
The present invention relates to a method to treat a grafts, implant, scaffold, and constructs, including allografts, xenografts, autografts, and prosthetics comprising collagen, with an inhibitor of collagen cross-links and/or advanced glycation endproducts (AGE), in order to alleviate the mechanical weakness induced by the cross-links The invention also provides for kits for use in the operating theater during autograft, allograft or xenograft procedures, or for preparing allograft, xenografts or prosthetics that have not been already treated prior to packaging. The kit comprises a first agent or agents that inhibit collagen cross-links and/or advanced glycation endproducts, instructions for use, optionally a wash or rinse agent, and a device for containing the graft and first agent.

Porous Non-Biodegradable Hydrogel Admixed With A Chemoattractant For Tissue Replacement

US Patent:
2009001, Jan 15, 2009
Filed:
Aug 15, 2006
Appl. No.:
11/997453
Inventors:
Anthony Lowman - Wallingford PA, US
Suzanne A. Maher - New York NY, US
Lorenzo Pio Serino - Reggello, IT
Kara Spiller - Philadelphia PA, US
Peter A. Torzilli - Ridgefield CT, US
International Classification:
A61L 27/58
US Classification:
424426
Abstract:
A non-biodegradable hydrogel matrix containing microspheres of a biodegradable polymer for the purpose of treating, repairing, or replacing damaged biological tissue is described. The biodegradable phase can be admixed with a chemoattractant. Examples of degradable polymers include degradable polyesters such as 50:50 PLA:PGA, the degradation profiles of which are well characterized. The matrix is permanently inserted into a tissue defect to provide mechanical support before, during, and after tissue ingrowth.

Multi-Component Non-Biodegradable Implant, A Method Of Making And A Method Of Implantation

US Patent:
2017020, Jul 27, 2017
Filed:
Dec 6, 2016
Appl. No.:
15/370832
Inventors:
- New York NY, US
Tony Chen - New Brunswick NJ, US
Joseph D. Lipman - New York NY, US
Peter Torzilli - Ridgefield CT, US
Russell Warren - Greenwich CT, US
International Classification:
A61L 27/56
A61F 2/38
A61F 2/44
B29C 70/70
A61L 27/54
A61F 2/08
A61F 2/28
A61L 27/52
A61L 27/16
A61F 2/30
B29C 71/02
Abstract:
An implant comprising at least three components, namely, a solid hydrogel, a porous hydrogel adjacent to or surrounding the solid hydrogel (together considered “the hydrogel”), and a porous rigid base. The solid hydrogel and porous rigid base carry joint load, and the porous hydrogel layer and the porous rigid base allow for cellular migration into and around the implant. The invention is also a novel method of manufacturing the implant, a novel method of implanting the implant, and a method of treating, repairing or replacing biological tissue, more preferably musculoskeletal tissue, with the implant.

Multi-Component Non-Biodegradable Implant, A Method Of Making And A Method Of Implantation

US Patent:
2014032, Oct 30, 2014
Filed:
Apr 25, 2014
Appl. No.:
14/261821
Inventors:
- New York NY, US
Tony Chen - New York NY, US
Joseph D. Lipman - New York NY, US
Peter Torzilli - Ridgefield CT, US
Russell Warren - Greenwich CT, US
Assignee:
NEW YORK SOCIETY FOR THE RUPTURED AND CRIPPLED MAINTAINING THE HOSPITAL FOR SPECIAL SURGERY - New York NY
International Classification:
A61F 2/30
B29C 70/68
B29C 70/70
US Classification:
623 1412, 264 28
Abstract:
An implant comprising at least three components, namely, a solid hydrogel, a porous hydrogel adjacent to or surrounding the solid hydrogel (together considered “the hydrogel”), and a porous rigid base. The solid hydrogel and porous rigid base carry joint load, and the porous hydrogel layer and the porous rigid base allow for cellular migration into and around the implant. The invention is also a novel method of manufacturing the implant, a novel method of implanting the implant, and a method of treating, repairing or replacing biological tissue, more preferably musculoskeletal tissue, with the implant.

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