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Ralph J Bernacki Deceased250 Crag Burn Dr, East Aurora, NY 14052

Ralph Bernacki Phones & Addresses

250 Crag Burn Dr, East Aurora, NY 14052    716-6551838   

Cambridge, MA   

61 Dellwood Dr, Elma, NY 14059    716-6551838   

Erin, NY   

250 Crag Burn Dr, East Aurora, NY 14052    716-4627240   

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Ralph J Bernacki

Linkedin

Work

Company: Roswell park cancer institute Position: Professor

Education

Degree: Graduate or professional degree

Industries

Hospital & Health Care

Mentions for Ralph J Bernacki

Ralph Bernacki resumes & CV records

Resumes

Ralph Bernacki Photo 10

Professor At Roswell Park Cancer Institute

Position:
professor at Roswell Park Cancer Institute, Professor Pharmacology at SUNY Buffalo/Roswell Park Cancer Insitute
Location:
Buffalo/Niagara, New York Area
Industry:
Hospital & Health Care
Work:
Roswell Park Cancer Institute
professor
SUNY Buffalo/Roswell Park Cancer Insitute since 1972
Professor Pharmacology

Publications & IP owners

Us Patents

Fluorinated Glucosamine Analogs Useful For Modulating Post-Translational Glycosylations On Cells

US Patent:
7098195, Aug 29, 2006
Filed:
Nov 26, 2002
Appl. No.:
10/305812
Inventors:
Robert Sackstein - Sudbury MA, US
Charles J. Dimitroff - Williamsville NY, US
Ralph J. Bernacki - Elma NY, US
Moheswar Sharma - Amherst NY, US
Khushi L. Matta - Williamsville NY, US
Brajeswar Paul - Williamsville NY, US
Assignee:
Health Research, Inc. - Buffalo NY
The Brigham and Women's Hospital, Inc. - Boston MA
International Classification:
A61K 31/7008
A61K 31/573
A61K 31/415
A61K 31/192
US Classification:
514 62, 514161, 514171, 514406, 514570, 536 53, 435 724
Abstract:
The present invention provides compositions and methods for inhibiting cell migration, e. g. , lymphocytes and inflammation. The invention also provides an improved process for preparing fluorinated N-acetylglucosamines.

Fluorinated Glucosamine Analogs Useful For Modulating Post-Translational Glyscosylations On Cells

US Patent:
2006028, Dec 14, 2006
Filed:
Aug 23, 2006
Appl. No.:
11/508566
Inventors:
Robert Sackstein - Sudbury MA, US
Charles Dimitroff - Brookline MA, US
Ralph Bernacki - Elma NY, US
Moheswar Sharma - Amherst NY, US
Khushi Matta - Williamsville NY, US
Brajeswar Paul - Williamsville NY, US
International Classification:
A61K 31/7008
US Classification:
514062000
Abstract:
The present invention provides compositions and methods for inhibiting cell migration, e.g., lymphocytes and inflammation. The invention also provides an improved process for preparing fluorinated N-acetylglucosamines.

Taxoid Reversal Agents For Drug-Resistance In Cancer Chemotherapy And Pharmaceutical Compositions Thereof

US Patent:
5811452, Sep 22, 1998
Filed:
Jan 8, 1997
Appl. No.:
8/780633
Inventors:
Iwao Ojima - Stony Brook NY
Ralph J. Bernacki - Elma NY
Assignee:
The Research Foundation of State University of New York - Albany NY
Health Research Inc - Buffalo NY
International Classification:
A61K 31335
C07D30514
US Classification:
514449
Abstract:
The present invention is directed to novel taxoids possessing strong reversing activities for drug-resistance associated with anti-cancer agents, the preparation of these reversal agents and pharmaceutical compositions thereof. The new taxoids of the present invention have the formula (I). ##STR1##.

2-Substituted Arabinopyranosyl Nucleosides And Nucleotides

US Patent:
4918056, Apr 17, 1990
Filed:
Oct 14, 1986
Appl. No.:
6/918372
Inventors:
Miroslav V. Bobek - Williamsville NY
Seung-Ho An - Williamsville NY
Ralph J. Bernacki - Elma NY
Assignee:
Health Research, Inc. (Roswell Park Division) - Buffalo NY
International Classification:
A61K 3170
C07H 1502
US Classification:
514 25
Abstract:
Novel arabinopyranosyl nucleoside derivatives having the heterocyclic moiety and fluorine at the 2' position of the sugar ring (pyranose configuration), which have antitumor, antiviral and antimicrobial properties, are prepared by condensation of a pyrimidine, purine or 1,3-oxazine base with an acylated 2-deoxy-2,2-difluoro-D-arabinopyranoside and/or acylated 2-deoxy-2-bromo-2-fluoro-D-arabinopyranoside.

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