Robert Babine resumes & CV records
Resumes
President (Founder) And Chief Scientist - Rebexsess, Llc
Location:
Greater San Diego Area
Industry:
Biotechnology
Robert E Babine, 697819 Estancia St, Carlsbad, CA 92009
Robert Babine Phones & Addresses
7819 Estancia St, Carlsbad, CA 92009 760-9430403
1655 Corte Orchidia, Carlsbad, CA 92011 760-9430403
105 Sunlit Dr W, Santa Fe, NM 87508
19 Concetta Way, Franklin, MA 02038
Warwick, RI
Indianapolis, IN
Lakewood, CO
San Diego, CA
Nanuet, NY
Houston, TX
7819 Estancia St, Carlsbad, CA 92009
Social networks
Robert E Babine
Linkedin
Work
Position:
Clerical/White Collar
Education
Degree:
High school graduate or higher
Emails
Industries
Biotechnology
Mentions for Robert E Babine
Publications & IP owners
Us Patents
Antipicornaviral Compounds And Methods For Their Use And Preparation
US Patent:
6362166, Mar 26, 2002
Filed:
Oct 13, 2000
Appl. No.:
09/689717
Inventors:
Stephen E. Webber - San Diego CA
Peter S. Dragovich - Encinitas CA
Thomas J. Prins - Cardiff CA
Siegfried H. Reich - San Diego CA
Ethel S. Littlefield - San Diego CA
Joseph T. Marakovits - Encinitas CA
Robert E. Babine - Carlsbad CA
Ted M. Bleckman - La Jolla CA
Peter S. Dragovich - Encinitas CA
Thomas J. Prins - Cardiff CA
Siegfried H. Reich - San Diego CA
Ethel S. Littlefield - San Diego CA
Joseph T. Marakovits - Encinitas CA
Robert E. Babine - Carlsbad CA
Ted M. Bleckman - La Jolla CA
Assignee:
Agouron Pharmaceuticals, Inc. - La Jolla CA
International Classification:
A61K 3148
US Classification:
514 19, 548230, 548235, 548247, 549478, 549483, 549488, 560 27, 560122, 560128
Abstract:
Picornaviral 3C protease inhibitors, obtainable by chemical synthesis, inhibit or block the biological activity of picornaviral 3C proteases. These compounds, as well as pharmaceutical compositions that contain these compounds, are suitable for treating patients or hosts infected with one or more picornaviruses. Several novel methods and intermediates can be used to prepare the novel picornaviral 3C protease inhibitors of the present invention.
Compounds And Methods For Treatment Of Thrombosis
US Patent:
7217794, May 15, 2007
Filed:
Apr 2, 2004
Appl. No.:
10/817248
Inventors:
Sherin S. Abdel-Meguid - Exton PA, US
Robert E. Babine - Franklin MA, US
Hongfeng Deng - Acton MA, US
Lei Jin - Wellesley MA, US
Jian Lin - Walpole MA, US
Scott R. Magee - Somerville MA, US
Harold V. Meyers - Weston MA, US
Pramod Pandey - Canton MA, US
Michael J. Rynkiewicz - Boston MA, US
David T. Weaver - Newton MA, US
Zihong Gho - Southbury CT, US
Thomas D. Bannister - Northborough MA, US
Robert E. Babine - Franklin MA, US
Hongfeng Deng - Acton MA, US
Lei Jin - Wellesley MA, US
Jian Lin - Walpole MA, US
Scott R. Magee - Somerville MA, US
Harold V. Meyers - Weston MA, US
Pramod Pandey - Canton MA, US
Michael J. Rynkiewicz - Boston MA, US
David T. Weaver - Newton MA, US
Zihong Gho - Southbury CT, US
Thomas D. Bannister - Northborough MA, US
Assignee:
Daiamed, Inc. - Cambridge MA
International Classification:
C07K 14/745
C07K 1/00
C07K 14/00
C07K 1/00
C07K 14/00
US Classification:
530384, 530350, 530380, 530381, 530412
Abstract:
The present invention provides compounds that inhibit Factor XIa and methods of preventing or treating undesired thrombosis by administering a compound of the invention to a mammal. The invention also provides three-dimensional structures of Factor XIa and methods for designing or selecting additional Factor XIa inhibitors using these structures.
Peptidomimetic Protease Inhibitors
US Patent:
7820671, Oct 26, 2010
Filed:
Aug 31, 2001
Appl. No.:
10/344112
Inventors:
Robert Edward Babine - Carlsbad CA, US
Shu Hui Chen - Thousand Oaks CA, US
Ivan Collado - Madrid, ES
Cristina Garcia-Paredes - Madrid, ES
John Irvin Glass - Germantown MD, US
Deqi Guo - Carmel IN, US
Ling Jin - Indianapolis IN, US
Jason Eric Lamar - Indianapolis IN, US
Nancy June Snyder - Lizton IN, US
Xicheng David Sun - Broumfied CO, US
Mark Joseph Tebbe - Zionsville IN, US
Frantz Victor - Indianapolis IN, US
Yvonne Yee Mai Yip - Indianapolis IN, US
Robert B. Perni - Marlborough MA, US
Luc Farmer - Foxborough MA, US
Shu Hui Chen - Thousand Oaks CA, US
Ivan Collado - Madrid, ES
Cristina Garcia-Paredes - Madrid, ES
John Irvin Glass - Germantown MD, US
Deqi Guo - Carmel IN, US
Ling Jin - Indianapolis IN, US
Jason Eric Lamar - Indianapolis IN, US
Nancy June Snyder - Lizton IN, US
Xicheng David Sun - Broumfied CO, US
Mark Joseph Tebbe - Zionsville IN, US
Frantz Victor - Indianapolis IN, US
Yvonne Yee Mai Yip - Indianapolis IN, US
Robert B. Perni - Marlborough MA, US
Luc Farmer - Foxborough MA, US
Assignee:
Vertex Pharmaceuticals Incorporated - Cambridge MA
International Classification:
A61K 31/497
C07D 241/02
C07D 241/02
US Classification:
5142521, 544406
Abstract:
The present invention relates to peptidomimetic compounds useful as protease inhibitors, particularly as serine protease inhibitors and more particularly as hepatitis C NS3 protease inhibitors; intermediates thereto; their preparation including novel steroselective processes to intermediates. The invention is also directed to pharmaceutical compositions and to methods for using the compounds for inhibiting HCV protease or treating a patient suffering from an HCV infection or physiological condition related to the infection. Also provided are pharmaceutical combinations comprising, in addition to one or more HCV serine protease inhibitors, one or more interferons exhibiting anti-HCV activity and/or one or more compounds having anti HCV activity and a pharmaceutically acceptable carrier, and methods for treating or preventing a HCV infection in a patient using the compositions. The present invention is also directed to a kit or pharmaceutical pack for treating or preventing HCV infection in a patient.
Peptidomimetic Protease Inhibitors
US Patent:
8252923, Aug 28, 2012
Filed:
Sep 8, 2008
Appl. No.:
12/231982
Inventors:
Robert Edward Babine - Franklin MA, US
Shu-Hui Chen - Carmel IN, US
Jason Eric Lamar - Indianapolis IN, US
Nancy June Snyder - Lizton IN, US
Xicheng Sun - Superior CO, US
Mark Joseph Tebbe - Hamburg, DE
Frantz Victor - Indianapolis IN, US
Yvonne Yee Mai Yip - Indianapolis IN, US
Ivan Collado - Madrid, ES
Cristina Garcia-Paredes - Madrid, ES
Ling Jin - Carmel IN, US
Deqi Guo - Carmel IN, US
John Irvin Glass - Indianapolis IN, US
Shu-Hui Chen - Carmel IN, US
Jason Eric Lamar - Indianapolis IN, US
Nancy June Snyder - Lizton IN, US
Xicheng Sun - Superior CO, US
Mark Joseph Tebbe - Hamburg, DE
Frantz Victor - Indianapolis IN, US
Yvonne Yee Mai Yip - Indianapolis IN, US
Ivan Collado - Madrid, ES
Cristina Garcia-Paredes - Madrid, ES
Ling Jin - Carmel IN, US
Deqi Guo - Carmel IN, US
John Irvin Glass - Indianapolis IN, US
Assignee:
Vertex Pharmaceuticals Incorporated - Cambridge MA
International Classification:
C07D 265/34
C07D 241/08
C07D 275/06
C07D 417/02
C07D 233/32
C07D 403/02
C07D 207/08
C07D 493/14
C07C 229/00
C07D 241/08
C07D 275/06
C07D 417/02
C07D 233/32
C07D 403/02
C07D 207/08
C07D 493/14
C07C 229/00
US Classification:
544101, 544173, 544408, 548207, 548208, 5483121, 5483225, 548530, 549387, 560 37
Abstract:
The present invention relates to peptidomimetic compounds useful as protease inhibitors, particularly as serine protease inhibitors and more particularly as hepatitis C NS3 protease inhibitors; intermediates thereto; their preparation including novel steroselective processes to intermediates. The invention is also directed to pharmaceutical compositions and to methods for using the compounds for inhibiting HCV protease or treating a patient suffering from an HCV infection or physiological condition related to the infection. Also provided are pharmaceutical combinations comprising, in addition to one or more HCV serine protease inhibitors, one or more interferons exhibiting anti-HCV activity and/or one or more compounds having anti HCV activity and a pharmaceutically acceptable carrier, and methods for treating or preventing a HCV infection in a patient using the compositions. The present invention is also directed to a kit or pharmaceutical pack for treating or preventing HCV infection in a patient.
Modulators Of Retinoid-Related Orphan Receptor Gamma
US Patent:
8389739, Mar 5, 2013
Filed:
May 24, 2011
Appl. No.:
13/114616
Inventors:
Scott Thacher - San Diego CA, US
Xiaolin Li - San Diego CA, US
Robert Babine - Carlsbad CA, US
Bruno Tse - San Diego CA, US
Xiaolin Li - San Diego CA, US
Robert Babine - Carlsbad CA, US
Bruno Tse - San Diego CA, US
Assignee:
Orphagen Pharmaceuticals - San Diego CA
International Classification:
C07D 249/08
C07D 249/00
C07D 251/00
C07D 251/40
A01N 41/06
A01N 37/00
A61K 31/58
C07D 249/00
C07D 251/00
C07D 251/40
A01N 41/06
A01N 37/00
A61K 31/58
US Classification:
5482622, 5482624, 544180, 544194, 514604, 514172, 514510
Abstract:
Methods for modulating (inhibiting or stimulating) retinoid-related orphan receptor γ (RORγ) activity. This modulation has numerous effects, including inhibition of T-17 cell function and/or T-17 cell activity, and inhibition of re-stimulation of T-17 cells, which are beneficial to treatment of inflammation and autoimmune disorders. Stimulation of RORγ results in stimulation of T-17 cell function and/or activity which is beneficial for immune-enhancing compositions (e. g. , vaccines).
Peptidomimetic Protease Inhibitors
US Patent:
8529882, Sep 10, 2013
Filed:
Jul 3, 2012
Appl. No.:
13/541436
Inventors:
Robert Edward Babine - Franklin MA, US
Shu Hui Chen - Carmel IN, US
Ivan Collado - Madrid, ES
Cristina Garcia-Paredes - Madrid, ES
John Irvin Glass - Indianapolis IN, US
Ling Jin - Carmel IN, US
Jason Eric Lamar - Indianapolis IN, US
Nancy June Snyder - Lizton IN, US
Xicheng David Sun - Superior CO, US
Deqi Guo - Carmel IN, US
Yvonne Yee Mai Yip - Indianapolis IN, US
Frantz Victor - Indianapolis IN, US
Mark Joseph Tebbe - Hamburg, DE
Robert B. Perni - Marlborough MA, US
Luc Farmer - Montreal, CA
Shu Hui Chen - Carmel IN, US
Ivan Collado - Madrid, ES
Cristina Garcia-Paredes - Madrid, ES
John Irvin Glass - Indianapolis IN, US
Ling Jin - Carmel IN, US
Jason Eric Lamar - Indianapolis IN, US
Nancy June Snyder - Lizton IN, US
Xicheng David Sun - Superior CO, US
Deqi Guo - Carmel IN, US
Yvonne Yee Mai Yip - Indianapolis IN, US
Frantz Victor - Indianapolis IN, US
Mark Joseph Tebbe - Hamburg, DE
Robert B. Perni - Marlborough MA, US
Luc Farmer - Montreal, CA
Assignee:
Vertex Pharmaceuticals Incorporated - Cambridge MA
International Classification:
A61K 38/07
A61K 38/20
A61K 38/21
C07D 209/52
C12N 5/073
C12N 9/99
A61P 31/14
C07K 5/117
A61K 38/20
A61K 38/21
C07D 209/52
C12N 5/073
C12N 9/99
A61P 31/14
C07K 5/117
US Classification:
424 852, 424 854, 424 857, 435184, 435375, 517 43, 530330, 548515
Abstract:
The present invention relates to peptidomimetic compounds useful as protease inhibitors, particularly as serine protease inhibitors and more particularly as hepatitis C NS3 protease inhibitors; intermediates thereto; their preparation including novel stereoselective processes to intermediates. The invention is also directed to pharmaceutical compositions and to methods for using the compounds for inhibiting HCV protease or treating a patient suffering from an HCV infection or physiological condition related to the infection. Also provided are pharmaceutical combinations comprising, in addition to one or more HCV serine protease inhibitors, one or more interferons exhibiting anti-HCV activity and/or one or more compounds having anti HCV activity and a pharmaceutically acceptable carrier, and methods for treating or preventing a HCV infection in a patient using the compositions. The present invention is also directed to a kit or pharmaceutical pack for treating or preventing HCV infection in a patient.
Compounds And Methods For Treatment Of Thrombosis
US Patent:
2008014, Jun 19, 2008
Filed:
Jul 22, 2005
Appl. No.:
11/658121
Inventors:
Hongfeng Deng - Acton MA, US
Jian Lin - Walpole MA, US
Zihong Guo - Southbury CT, US
Harold V. Meyers - Weston MA, US
Sherin S. Abdel-Meguid - Exton PA, US
Robert E. Babine - Carlsbad CA, US
Jian Lin - Walpole MA, US
Zihong Guo - Southbury CT, US
Harold V. Meyers - Weston MA, US
Sherin S. Abdel-Meguid - Exton PA, US
Robert E. Babine - Carlsbad CA, US
International Classification:
C07D 401/12
C07D 209/14
C07D 209/14
US Classification:
5462774, 548495
Abstract:
The invention provides compounds, pharmaceutical compositions, and methods for the treatment of thromboembolic disorders, such as, for example, arterial cardiovascular thromboembolic disorders, venous cardiovascular thromboembolic disorders, or thromboembolic disorders in the chambers of the heart.
Peptidomimetic Protease Inhibitors
US Patent:
2012006, Mar 15, 2012
Filed:
Nov 10, 2011
Appl. No.:
13/293812
Inventors:
ROBERT EDWARD BABINE - FRANKLIN MA, US
SHU HUI CHEN - CARMEL IN, US
IVAN COLLADO - MADRID, ES
CRISTINA GARCIA-PAREDES - MADRID, ES
JOHN IRVIN GLASS - INDIANAPOLIS IN, US
DEQI GUO - CARMEL IN, US
LING JIN - CARMEL IN, US
JASON ERIC LAMAR - INDIANAPOLIS IN, US
NANCY JUNE SNYDER - LIZTON IN, US
XICHENG DAVID SUN - SUPERIOR CO, US
YVONNE YEE MAI YIP - INDIANAPOLIS IN, US
FRANTZ VICTOR - INDIANAPOLIS IN, US
MARK JOSEPH TEBBE - HAMBURG, DE
ROBERT B. PERNI - MARLBOROUGH MA, US
LUC FARMER - FOXBOROUGH MA, US
SHU HUI CHEN - CARMEL IN, US
IVAN COLLADO - MADRID, ES
CRISTINA GARCIA-PAREDES - MADRID, ES
JOHN IRVIN GLASS - INDIANAPOLIS IN, US
DEQI GUO - CARMEL IN, US
LING JIN - CARMEL IN, US
JASON ERIC LAMAR - INDIANAPOLIS IN, US
NANCY JUNE SNYDER - LIZTON IN, US
XICHENG DAVID SUN - SUPERIOR CO, US
YVONNE YEE MAI YIP - INDIANAPOLIS IN, US
FRANTZ VICTOR - INDIANAPOLIS IN, US
MARK JOSEPH TEBBE - HAMBURG, DE
ROBERT B. PERNI - MARLBOROUGH MA, US
LUC FARMER - FOXBOROUGH MA, US
Assignee:
VERTEX PHARMACEUTICALS INCORPORATED - CAMBRIDGE MA
International Classification:
A61K 38/08
C07K 5/037
A61K 38/21
C12N 5/071
C07C 229/42
C07D 209/52
C12N 9/99
C07K 7/06
A61K 38/20
C07K 5/037
A61K 38/21
C12N 5/071
C07C 229/42
C07D 209/52
C12N 9/99
C07K 7/06
A61K 38/20
US Classification:
424 852, 530330, 514 37, 424 854, 424 857, 560 43, 548512, 548515, 435184, 435375
Abstract:
The present invention relates to peptidomimetic compounds useful as protease inhibitors, particularly as serine protease inhibitors and more particularly as hepatitis C NS3 protease inhibitors; intermediates thereto; their preparation including novel steroselective processes to intermediates. The invention is also directed to pharmaceutical compositions and to methods for using the compounds for inhibiting HCV protease or treating a patient suffering from an HCV infection or physiological condition related to the infection. Also provided are pharmaceutical combinations comprising, in addition to one or more HCV serine protease inhibitors, one or more interferons exhibiting anti-HCV activity and/or one or more compounds having anti HCV activity and a pharmaceutically acceptable carrier, and methods for treating or preventing a HCV infection in a patient using the compositions. The present invention is also directed to a kit or pharmaceutical pack for treating or preventing HCV infection in a patient.
Isbn (Books And Publications)
Protein Crystallography In Drug Discovery
Author:
Robert E. Babine
ISBN #:
3527306781
NOTICE: You may not use BackgroundCheck or the information it provides to make decisions about employment, credit, housing or any other purpose that would require Fair Credit Reporting Act (FCRA) compliance. BackgroundCheck is not a Consumer Reporting Agency (CRA) as defined by the FCRA and does not provide consumer reports.