Robert H Grubbs, 821700 Spruce St, South Pasadena, CA 91030

6376690, Apr 23, 2002

Aug 30, 1999

09/386205

Robert H. Grubbs - Pasadena CA
Heather D. Maynard - Pasadena CA
David M. Lynn - Somerville MA

California Institute O Technology - Pasadena CA

C07F 1500

556 21, 556136

The present invention generally relates to the discovery that the solubility of metal complexes may be readily manipulated by the addition of one or more solubility-enhancing compounds. This manipulation of the solubilities allows for the preparation of suitable samples for precise quantitative analysis and for the facile purification of the desired products from the reaction mixture containing one or more metal complexes. In one embodiment of the invention, the relative solubilities between two solutions are manipulated so as cause the metal complex found in a first solution to transfer to a second solution that is generally immiscible with the first solution. The metal complex is thus separated from the reaction mixture which comprises the first solution by the removal of the second solution. In another embodiment, the solubility-enhancing compounds of the present invention is used to prepare samples containing metal complexes for precise quantitative analysis such as inductively coupled plasma mass spectroscopy.

6383319, May 7, 2002

Aug 4, 1999

09/369051

Ronald W. Humble - Colorado Springs CO
Robert H. Grubbs - South Pasadena CA
Charles S. Woodson - Conroe TX

A.P.T. Aerospace, L.L.C. - Monroe LA

C06B 2700

149 87, 1491092, 44354

Preferred embodiments of the present invention relate to rocket fuels comprising metal hydrides and poly-dicyclopentadiene (âpoly-DCPDâ). Although poly-DCPD also has physical and chemical properties that are compatible with being used as a rocket fuel in its own right, its primary function is as a binder for the metal hydride. Illustrative examples of metal hydrides include but are not limited to as aluminum hydrides, lithium hydrides, and lithium aluminum hydrides.

6410664, Jun 25, 2002

Jan 15, 1998

09/007443

Donald Albert Bansleben - Columbia MD
Stefan K. Friedrich - San Gabriel CA
Todd Ross Younkin - Pasadena CA
Robert Howard Grubbs - South Pasadena CA
Chunming Wang - Highland Park NJ
Robert Tan Li - Longview TX

Cryovac, Inc. - Duncan SC

C08F 4602

526141, 526161, 5261691, 526172, 526147, 526 91, 526129, 526139, 526140, 526142, 526145, 526146, 526281

The present invention is directed to processes of polymerization of olefins and copolymerization of olefins and functionalized olefins in the presence of certain late transition metal bidentate salicylaldimine chelates represented by the formula: wherein each of the symbols R, R , R , R , R , R , R , L, M, A, X and z are defined within the specification herein below.

6410666, Jun 25, 2002

Mar 17, 2000

09/527757

Robert H. Grubbs - South Pasadena CA
Christopher W. Bielawski - Pasadena CA

California Institute of Technology - Pasadena CA

C08F 444

526171, 526172, 526308, 526319, 526281, 526296, 5263031, 526315, 5263171, 526336, 526347, 5253261, 525360, 525367, 525371

The invention discloses a method for preparing a tri block copolymer of the formula: comprising: (a) contacting a cycloalkene with a chain transfer agent of the formula: âin the presence of a metal carbene metathesis catalyst to form a telechelic polymer; and (d) contacting the telechelic polymer with an alkene of the formula âin the presence of an ATRP organometallic catalyst wherein n and m are integers; Z is an ATRP initiator and âY Yâ is an alkenyl group; and, Râ is selected from the group consisting of aryl, nitrile and C -C carboxylate, wherein Râ is substituted or unsubstituted. The invention also discloses a method for preparing a diblock copolymer. In addition, the invention encompasses a triblock copolymer having no 1,2-PBD structure in the PBD portion of the copolymer.

6414097, Jul 2, 2002

Jul 31, 2001

09/919658

Robert H. Grubbs - South Pasadena CA
Daniel J. OLeary - Claremont CA
Helen E. Blackwell - Somerville MA

California Institute of Technology - Pasadena CA

C08F 426

526160, 526101, 526171, 526172, 502155, 556 22, 556136, 585511, 585514, 585523

A method for the cross-metathesis of terminal olefins is disclosed. The method describes making disubstituted internal olefin products by contacting a first terminal olefin with another first terminal olefin to form a dimer and then contacting the dimer with a second terminal olefin in the presence of a catalyst having the formula where M may be Os or Ru, R and R may be the same or different and may be hydrogen or a substitutent group selected from C -C alkyl, C -C alkenyl, C -C alkynyl, aryl, C C carboxylate, C -C alkoxy, C -C alkenyloxy, C -C alkynyloxy, aryloxy, C -C alkoxycarbonyl, C -C alkylthio, C -C alkylsulfonyl, and C -C alkylsulfinyl. X and X may be the same or different and may be any anionic ligand. L and L may be the same or different and may be any neutral electron donor.

6426419, Jul 30, 2002

Mar 31, 2000

09/539840

Robert H. Grubbs - South Pasadena CA
Tina M. Trinka - Pasadena CA

California Institute of Technology - Pasadena CA

C07F 1500

548101, 5482622, 556136, 556 22, 502155, 526171

The invention discloses ruthenium alkylidene complexes of the type (PCy )(L)Cl Ru(CHPh), where L is a triazolylidene ligand of the general formula: These catalysts have been found to be considerably more active for olefin metathesis at elevated temperatures than the parent catalyst (PCy ) Cl Ru(CHPh)(2). For example, complex 14 (L=1,3,4-triphenyl-4. 5-dihydro-1H-triazol-5-ylidene) is able to catalyze the ring-closing metathesis of substituted dienes to give tetra-substituted cyclic olefins in good yield. In addition, this complex demonstrates the analogous stability towards oxygen and moisture exhibited by ruthenium alkylidene 2.

6433101, Aug 13, 2002

Dec 2, 1999

09/453020

Charles S. Woodson - Conroe TX
Marc A. Hillmyer - Minneapolis MN
Robert H. Grubbs - South Pasadena CA
Timothy P. Lodge - Minneapolis MN
Yu Ren - Minneapolis MN

Regents of the University of Minnesota - Minneapolis MN
Cymetech, LLC - Huntsville TX

C08F 818

5253321, 5253323, 5253591, 5253595

The present invention relates to the post-polymerization fluorination methods of polymers produced via ring-opening metathesis polymerization. Unlike prior art methods that result in low product yields and generally involve chemically aggressive reagents, the inventive methods produce fluorinated polymers in quantitative yields and under mild conditions. In preferred embodiments, a source of difluorocarbene is reacted with the desired polydiene to form a fluorinated polymer product. In preferred embodiments, the source of difluorocarbene is hexafluoropropylene oxide and the polydiene is poly-dicyclopentadiene (âpoly-DCPDâ). Fluorination and the concomitant removal of unsaturated bonds result in polymers having improved physical properties such as improved strength characteristics, enhanced oxidative and chemical stability, and low surface energies.

6450642, Sep 17, 2002

Oct 8, 1999

09/416044

Jagdish M. Jethmalani - Pasadena CA
Robert H. Grubbs - South Pasadena CA
Christian A. Sandstedt - Pasadena CA
Julia A. Kornfield - Pasadena CA
Daniel M. Schwartz - San Francisco CA

California Institute of Technology - Pasadena CA
The Regents of the University of California - Oakland CA

A61B 300

351219, 351159, 351160 R, 351161, 623 611

The present invention relates to lenses that are capable of post-fabrication power modifications. In general, the inventive lenses comprise (i) a first polymer matrix and (ii) a refraction modulating composition that is capable of stimulus-induced polymerization dispersed therein. When at least a portion of the lens is exposed to an appropriate stimulus, the refraction modulating composition forms a second polymer matrix. The amount and location of the second polymer matrix may modify a lens characteristic such as lens power by changing its refractive index and/or by altering its shape. The inventive lenses have a number of applications in the electronics and medical fields as data storage means and as medical lenses, particularly intraocular lenses, respectively.