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Roger D Sloboda, 77150 Greensboro Rd, Hanover, NH 03755

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150 Greensboro Rd, Hanover, NH 03755   

Falmouth, MA   

Etna, NH   

Milton, MA   

14 Elm Rd, Falmouth, MA 02540   

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Us Patents

Compositions And Methods For Destabilizing Lysosomes To Increase Oncogenic Or Aberrant Protein Degradation

US Patent:
2006022, Oct 12, 2006
Filed:
Jul 30, 2004
Appl. No.:
10/564070
Inventors:
Sutisak Kitareewan - Ordford NH, US
Roger Sloboda - Hanover NH, US
Ethan Dmitrovsky - Hanover NH, US
International Classification:
C12Q 1/37
A61K 31/4745
A61K 31/203
A61K 33/36
US Classification:
424620000, 514304000, 514559000, 435023000
Abstract:
The present invention relates to compositions and methods for destabilizing lysosomes to increase the degradation of oncogenic or aberrant proteins for the prevention and treatment of disease. Methods for identifying agents which destabilize lysosomes are also provided as are agents identified in accordance with the screening method.

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