Rudolph L Juliano DeceasedBoone, NC
Rudolph Juliano Phones & Addresses
Boone, NC
105 Standish Dr, Chapel Hill, NC 27514 919-9697955
Port Richey, FL
105 Standish Dr, Chapel Hill, NC 27517 919-3660615
Work
Position:
Building and Grounds Cleaning and Maintenance Occupations
Education
Degree:
High school graduate or higher
Emails
Mentions for Rudolph L Juliano
Publications & IP owners
Us Patents
Selective Killing Of Cancerous Cells
US Patent:
2006001, Jan 26, 2006
Filed:
Jul 14, 2005
Appl. No.:
11/181390
Inventors:
Rudolph Juliano - Chapel Hill NC, US
Dong Xu - Chapel Hill NC, US
Vidula Dixit - Chapel Hill NC, US
Dong Xu - Chapel Hill NC, US
Vidula Dixit - Chapel Hill NC, US
Assignee:
The University of North Carolina - Chapel Hill NC
International Classification:
A61K 48/00
C12N 15/85
C12N 15/85
US Classification:
514044000, 435455000
Abstract:
The presently disclosed subject matter provides methods for selectively conferring toxicity on cancerous cells. Also provided are systems and kits that can be employed for performing the disclosed method.
Methods For The Delivery Of Oligomeric Compounds
US Patent:
2008019, Aug 21, 2008
Filed:
May 13, 2005
Appl. No.:
11/596238
Inventors:
Rudolph L. Juliano - Chapel Hill NC, US
Hyunmin Kang - Chapel Hill NC, US
Piet Herdewijn - Wezemaal, BE
Patrick Chaltin - Geldenaken, BE
Arthur Van Aerschot - Heist-op-den-Berg, BE
Hyunmin Kang - Chapel Hill NC, US
Piet Herdewijn - Wezemaal, BE
Patrick Chaltin - Geldenaken, BE
Arthur Van Aerschot - Heist-op-den-Berg, BE
International Classification:
C12N 15/00
C12N 5/00
C12N 5/00
US Classification:
435440, 435325
Abstract:
The presently disclosed subject matter relates to the delivery of oligonucleotides to cells through the delivery of a composition or reagent comprising a hybridization complex comprising a first antisense oligonucleotide which is modified to have a higher stability against degradation, and a second sense oligonucleotide which is prone to degradation. The presently disclosed subject matter furthermore relates to dendrimeric bioconjugates and compositions or reagents comprising them, wherein the bioconjugate comprises a conjugate moiety coupled to a dendrimeric structure and to their use to deliver oligomeric compounds including oligonucleotides or duplexes, as described above, to cells for modulation of gene expression (i.e. antisense or antigene therapy/research, RNA interference).
Receptor Targeted Oligonucleotides
US Patent:
2010028, Nov 4, 2010
Filed:
Oct 6, 2008
Appl. No.:
12/681260
Inventors:
Rudolph L. Juliano - Chapel Hill NC, US
Rowshon Alam - Needham MA, US
Vidula Dixit - Madison AL, US
Hyunmin Kang - Pomona CA, US
Xiaoyuan Chen - Potomac MD, US
Rowshon Alam - Needham MA, US
Vidula Dixit - Madison AL, US
Hyunmin Kang - Pomona CA, US
Xiaoyuan Chen - Potomac MD, US
International Classification:
A61K 31/7105
C12N 5/071
A61P 43/00
C12N 5/071
A61P 43/00
US Classification:
514 44 A, 435325
Abstract:
Disclosed herein are oligonucleotide conjugates that include ligands that target cell receptors that mediate endocytosis. The ligands can include peptides and small molecules. The conjugates can include carrier macromolecules to which the ligands and oligonucleotides are attached, or conjugates where an oligonucleotide is attached to a ligand in the absence of a carrier macromolecule. The oligonucleotides can include therapeutic oligonucleotides, such as siRNA, antisense RNA and miRNA. The ligand can be an RGD peptide. Also disclosed herein are methods of delivering the conjugates to cells in subjects.
Liposome-Incorporated Mepartricin
US Patent:
4981690, Jan 1, 1991
Filed:
Oct 27, 1987
Appl. No.:
7/114280
Inventors:
Reeta Mehta - Houston TX
Roy L. Hopfer - Houston TX
Rudolph L. Juliano - Chapel Hill NC
Roy L. Hopfer - Houston TX
Rudolph L. Juliano - Chapel Hill NC
Assignee:
Board of Regents, The University of Texas System - Austin TX
International Classification:
A61K 9127
US Classification:
424422
Abstract:
The present invention involves a liposomal agent for treating disseminated fungal infection in an animal. This liposomal agent comprises the polyene antifungal compound mepartricin. The mepatricin is encapsulated within a liposome. The liposome in which the mepartricin is incorporated is preferably a stable multilamellar vesicle. The liposome broadly comprises one or more lipids one or more of phosphomonoglyceride, phosphatidic acid and sphingolipid. The lipids are preferably one or more of phosphatidylcholine, phosphatidylserine, phosphatidylglycerol, sphingomyelin or phosphatidic acid. The lipids are most preferably one or more of dimyristoylphosphatidylchlorine, dimyristoylphosphatidylglycerol, phosphatidylcholine and phosphatidylglycerol. The liposome of the present invention may comprise a sterol most preferably cholesterol. An important aspect of the present invention involves a method for treating disseminated fungal infection in an animal.
Isbn (Books And Publications)
Targeted Drug Delivery
Author:
Rudolph L. Juliano
ISBN #:
0387528431
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