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Sandy A Simon, 5512540 12Th Ave NW, Seattle, WA 98177

Sandy Simon Phones & Addresses

12540 12Th Ave NW, Seattle, WA 98177    425-7531997   

La Jolla, CA   

Bronx, NY   

Kiona, WA   

Laurelton, NY   

Mentions for Sandy A Simon

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Sandy Simon Photo 1

Sandy Simon - Lawyer

ISLN:
921167691

Publications & IP owners

Us Patents

B-Cell Reduction Using Cd37-Specific And Cd20-Specific Binding Molecules

US Patent:
2007005, Mar 15, 2007
Filed:
Jul 25, 2006
Appl. No.:
11/493132
Inventors:
Laura Grosmaire - Hobart WA, US
Jeffrey Ledbetter - Shoreline WA, US
Peter Thompson - Bellevue WA, US
Sandy Simon - Seattle WA, US
William Brady - Bothell WA, US
Assignee:
TRUBION PHARMACEUTICALS, INC. - Seattle WA
International Classification:
A61K 39/395
US Classification:
424144100
Abstract:
The present invention generally provides methods for B-cell reduction in an individual using CD37-specific binding molecules. In particular, the invention provides methods for B-cell reduction using CD37-specific binding molecules alone, or a combination of CD37-specific binding molecules and CD20-specific binding molecules, in some instances a synergistic combination. The invention further provides materials and methods for treatment of diseases involving aberrant B-cell activity. In addition, the invention provides humanized CD37-specific binding molecules.

B-Cell Reduction Using Cd37-Specific And Cd20-Specific Binding Molecules

US Patent:
2008027, Nov 13, 2008
Filed:
Apr 11, 2008
Appl. No.:
12/101701
Inventors:
William Brady - Bothell WA, US
Jeffrey A. Ledbetter - Shoreline WA, US
Sandy A. Simon - Seattle WA, US
Peter A. Thompson - Bellevue WA, US
Assignee:
TRUBION PHARMACEUTICALS, INC. - Seattle WA
International Classification:
A61K 39/395
C07K 16/18
C12N 15/11
C12N 15/00
C12N 5/06
C12P 21/04
A61P 37/00
US Classification:
4241331, 4241381, 5303873, 536 2353, 4353201, 435365, 435 691
Abstract:
The present invention generally provides methods for B-cell reduction in an individual using CD37-specific binding molecules. In particular, the invention provides methods for B-cell reduction using CD37-specific binding molecules alone, or a combination of CD37-specific binding molecules and CD20-specific binding molecules, in some instances a synergistic combination. The invention further provides materials and methods for treatment of diseases involving aberrant B-cell activity. In addition, the invention provides humanized CD37-specific binding molecules.

B-Cell Reduction Using Cd37-Specific And Cd20-Specific Binding Molecules

US Patent:
2009021, Aug 27, 2009
Filed:
May 7, 2009
Appl. No.:
12/437507
Inventors:
Laura S. Grosmaire - Hobart WA, US
Jeffrey A. Ledbetter - Shoreline WA, US
Peter A. Thompson - Bellevue WA, US
Sandy A. Simon - Seattle WA, US
William Brady - Bothell WA, US
Assignee:
Trubion Pharmaceuticals, Inc. - Seattle WA
International Classification:
A61K 39/395
C07K 16/18
US Classification:
4241351, 5303873, 4241331
Abstract:
The present invention generally provides methods for B-cell reduction in an individual using CD37-specific binding molecules. In particular, the invention provides methods for B-cell reduction using CD37-specific binding molecules alone, or a combination of CD37-specific binding molecules and CD20-specific binding molecules, in some instances a synergistic combination. The invention further provides materials and methods for treatment of diseases involving aberrant B-cell activity. In addition, the invention provides humanized CD37-specific binding molecules.

Cd37 Immunotherapeutic And Combination With Bifunctional Chemotherapeutic Thereof

US Patent:
2009027, Nov 5, 2009
Filed:
Apr 13, 2009
Appl. No.:
12/422780
Inventors:
Phillip Tan - Lynnwood WA, US
Sandy A. Simon - Seattle WA, US
Charles G. Cerveny - Seattle WA, US
Christy Anne Nilsson - Sammamish WA, US
William Brady - Bothell WA, US
Jeffrey A. Ledbetter - Shoreline WA, US
Peter A. Thompson - Bellevue WA, US
Cecile Morales - Seattle WA, US
Assignee:
Trubion Pharmaceuticals, Inc. - Seattle WA
International Classification:
A61K 39/395
C07K 16/18
C07H 21/04
C12N 15/74
C12N 1/00
A61P 35/00
US Classification:
4241331, 5303873, 536 2353, 4353201, 435243
Abstract:
The present disclosure provides a humanized anti-CD37 small modular immunopharmaceutical (SMIP) molecule, as well as synergistic combination therapies of CD37-specific binding molecules (such as anti-CD37 SMIP proteins or antibodies) with bifunctional chemotherapeutics (such as bendamustine) that can be administered concurrently or sequentially, for use in treating or preventing B-cell related autoimmune, inflammatory, or hyperproliferative diseases.

Anti-Cd20 Therapeutic Compositions And Methods

US Patent:
2010033, Dec 30, 2010
Filed:
Jun 12, 2008
Appl. No.:
12/664166
Inventors:
Nitin K. Damle - Upper Saddle River NJ, US
Lioudmila Tchistiakova - Andover MA, US
Kyriaki Dunussi-Joannopoulos - Belmont MA, US
Sandy Alexander Simon - Seattle WA, US
William Brady - Bothell WA, US
Laura Sue Grosmaire - Hobart WA, US
Jeffrey Alan Ledbetter - Shoreline WA, US
Assignee:
Wyeth - Madison NJ
Trubion Pharmaceuticals Inc. - Seattle WA
International Classification:
A61K 39/395
C07K 16/28
C07H 21/00
C12N 15/63
C12N 5/10
C12P 21/02
G01N 33/566
A61P 37/02
A61P 29/00
A61P 25/00
A61P 35/00
US Classification:
4241351, 5303873, 4241331, 536 2353, 4353201, 435328, 435 696, 435 724
Abstract:
The present invention provides materials and methods for treatment of diseases involving aberrant B-cell activity, using a CD20-specific binding molecule, in particular, antibodies or antigen binding fragment thereof. The compositions disclosed herein is useful for the treatment and diagnosis of B-cell disorders, such as B-cell malignancies and autoimmune diseases.

Cd37 Immunotherapeutic And Combination With Bifunctional Chemotherapeutic Thereof

US Patent:
2011017, Jul 14, 2011
Filed:
Apr 11, 2009
Appl. No.:
12/678857
Inventors:
Philip Tan - Edmonds WA, US
Sandy Alexander Simon - Seattle WA, US
Charles G. Cerveny - Seattle WA, US
Christy Anne Nilsson - Sammamish WA, US
William Brady - Bothell WA, US
Jeffrey A. Ledbetter - Shoreline WA, US
Peter Armstrong Thompson - Bellevue WA, US
Cecile Morales - Seattle WA, US
Assignee:
TRUBION PHARMACEUTICALS, INC. - Seattle WA
International Classification:
A61K 39/395
C07K 16/00
A61P 35/00
US Classification:
4241331, 5303871, 4241301
Abstract:
The present disclosure provides a humanized anti-CD37 small modular immunopharmaceutical (SMIP) molecule, as well as synergistic combination therapies of CD37-specific binding molecules (such as anti-CD37 SMIP proteins or antibodies) with bifunctional chemotherapeutics (such as bendamustine) that can be administered concurrently or sequentially, for use in treating or preventing B cell related autoimmune, inflammatory, or hyperproliferative diseases.

Cd3 Immunotherapeutics And Uses Thereof

US Patent:
2013019, Aug 1, 2013
Filed:
Nov 15, 2012
Appl. No.:
13/678128
Inventors:
Philip TAN - Lynnwood WA, US
Sandy Alexander SIMON - Seattle WA, US
Charles G. CERVENY - Seattle WA, US
Christy Anne NILSSON - Sammamish WA, US
William BRADY - Bothell WA, US
Jeffrey A. LEDBETTER - Shoreline WA, US
Peter Armstrong THOMPSON - Bellevue WA, US
Cecile MORALES - Seattle WA, US
Assignee:
EMERGENT PRODUCT DEVELOPMENT SEATTLE, LLC - Seattle WA
International Classification:
C07K 16/46
US Classification:
4241331, 5303873
Abstract:
The present disclosure provides a humanized anti-CD37 small modular immunopharmaceutical (SMIP) molecule, as well as synergistic combination therapies of CD37-specific binding molecules (such as anti-CD37 SMIP proteins or antibodies) with bifunctional chemotherapeutics (such as bendamustine) that can be administered concurrently or sequentially, for use in treating or preventing B cell related autoimmune, inflammatory, or hyperproliferative diseases.

B-Cell Reduction Using Cd37-Specific And Cd20-Specific Binding Molecules

US Patent:
2013026, Oct 10, 2013
Filed:
Mar 15, 2013
Appl. No.:
13/836377
Inventors:
Jeffrey A. Ledbetter - Shoreline WA, US
Peter Armstrong Thompson - Bellevue WA, US
Sandy Alexander Simon - Seattle WA, US
William Brady - Bothell WA, US
International Classification:
C07K 16/30
US Classification:
4241331
Abstract:
The present invention generally provides methods for B-cell reduction in an individual using CD37-specific binding molecules. In particular, the invention provides methods for B-cell reduction using CD37-specific binding molecules alone, or a combination of CD37-specific binding molecules and CD20-specific binding molecules, in some instances a synergistic combination. The invention further provides materials and methods for treatment of diseases involving aberrant B-cell activity. In addition, the invention provides humanized CD37-specific binding molecules.

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