Srinivasan Sridharan, 4923951 Spalding Ave, Los Altos, CA 94024

6743388, Jun 1, 2004

Dec 31, 2001

10/038816

Srinivasan Sridharan - Morgan Hill CA
Murthy V. Simhambhatla - San Jose CA

Advanced Cardiovascular Systems, Inc. - Santa Clara CA

B29C 5504

264205, 2642105, 2642108, 26421113, 26421114, 2642356, 264291, 264346

A method including forming a semi-crystalline polymer material into a lamella; and stretching the lamella into a polymer including a node of folded lamella and a fibril orientation. A method including extruding a pseudo-gel including an ultrahigh molecular weight polyethylene material into a lamella; stretching the lamella into a polymer including a node of folded lamella and a fibril orientation; and annealing the polymer at a temperature sufficient to define the node and fibril orientation. An apparatus including a body portion formed of a dimension suitable for a medical device application and including a semi-crystalline polymer arrayed in a node of folded lamella and a fibril orientation. An apparatus including a body portion including an ultra-high molecular polyethylene material arrayed in a node of folded lamella and a fibril orientation.

6780361, Aug 24, 2004

Jun 17, 2002

10/174073

Srinivasan Sridharan - Morgan Hill CA
Murthy V. Simhambhatla - San Jose CA

Advanced Cardiovascular Systems, Inc. - Santa Clara CA

B29C 5504

264205, 2642101, 2642105, 2642106, 2642108, 26421116, 26421119, 264235, 2642356, 264237, 264291

A method including forming a pseudo-gel of a semi-crystalline polymer material and a solvent. The pseudo-gel is shaped into a first form and stretched. A portion of the solvent is removed to create a second form. The second form is stretched into a microstructure including nodes interconnected by fibrils. A method including forming a first form of a pseudo-gel including an ultra-high molecular weight polyethylene material and a solvent; stretching the first form; removing the solvent to form a second form; stretching the second form into a microstructure including nodes interconnected by fibrils; and annealing the stretched second form. An apparatus including a body portion formed of a dimension suitable for a medical device application and including a polyolefin polymer including a node and a fibril microstructure. An apparatus including a body portion including an ultra-high molecular weight polyolefin material including a node and a fibril microstructure.

6794462, Sep 21, 2004

Oct 8, 2002

10/266517

Srinivasan Sridharan - Morgan Hill CA
John Armstrong Young - Midlothian VA
Donald James Arthur - Chester VA
Thomas Yiu-Tai Tam - Richmond VA

Honeywell International Inc. - Morristown NJ

C08G 6380

525411, 525437

A composition comprises a solid-stated block copolymer of an aromatic polyester and a caprolactone, wherein the copolymer has been solid state polymerized such that intrinsic viscosity increases at least 20%, the caprolactone content decreases no more than 1. 2% absolute and the transesterification increases no more than 3. 5% absolute, and wherein the solid-stated copolymer has an intrinsic viscosity of at least 0. 82. Particularly preferred chain extension reactions are performed at a temperature of less than 175Â C. , and even more preferably at less than 165Â C. In further aspects of the inventive subject matter, yarns and methods of producing a fiber include contemplated solid-stated block copolymers.

6863757, Mar 8, 2005

Dec 19, 2002

10/326333

Fernando Gonzalez - Campbell CA, US
Srinivasan Sridharan - Morgan Hill CA, US
Delma M. Blankenship - Sunnyvale CA, US

Advanced Cardiovascular Systems, Inc. - Santa Clara CA

B32B031/00
B28B011/08
B29C049/08
B29C055/00

156 86, 264241, 264267, 264291

A method of making a catheter balloon or other expandable tubular medical device or component thereof formed of a compacted porous polymeric material, in which a tube of porous polymeric material is axially compacted, preferably without increasing the outer diameter of the tube, by positioning heat shrink material on the porous polymeric tube and heating the heat shrink material to decrease the length and diameter of the heat shrink material.

6866805, Mar 15, 2005

Dec 27, 2001

10/033380

James Hong - San Jose CA, US
Rahul Bhagat - San Jose CA, US
Syed Hossainy - Fremont CA, US
Santosh Prabhu - San Jose CA, US
Ashok Shah - San Jose CA, US
Srinivasan Sridharan - Morgan Hill CA, US

Advanced Cardiovascular Systems, Inc. - Santa Clara CA

B29C045/14
B29C070/70

264161, 264230, 2642711, 264278, 2642791, 264305, 264306, 623901

A hybrid stent is formed which exhibits both high flexibility and high radial strength. The expandable hybrid stent for implantation in a body lumen, such as a coronary artery, consists of radially expandable cylindrical rings generally aligned on a common longitudinal axis and interconnected by one or more links. In one embodiment, a dip-coated covered stent is formed by encapsulating cylindrical rings within a polymer material. In other embodiments, at least some of the rings and links are formed of a polymer material which provides longitudinal and flexural flexibility to the stent. These polymer rings and links are alternated with metallic rings and links in various configurations to attain sufficient column strength along with the requisite flexibility in holding open the target site within the body lumen. Alternatively, a laminated, linkless hybrid stent is formed by encapsulating cylindrical rings within a polymer tube.

6929768, Aug 16, 2005

May 13, 2002

10/144978

Srinivasan Sridharan - Morgan Hill CA, US
Bjorn G. Svensson - Morgan Hill CA, US

Advanced Cardiovascular Systems, Inc. - Santa Clara CA

B23K026/00

264400, 264482, 21912163, 21912164, 21912166, 21912182, 21912183

A method of making a catheter balloon or other expandable medical device, and a balloon or other device formed thereby, in which at least a portion of a tubular, wrapped sheet of polymeric material is heated with laser radiation to form a fused seam extending along at least a section of the length of the tubular body. In one embodiment, the portion of the sheet heated by laser radiation is less than the entire area of the sheet, so that the fused seam is formed by heating portions of the sheet without heating sections of the sheet spaced apart from the fused seam. In one embodiment, the sheet of polymeric material comprises a polymer having a porous and preferably a node and fibril microstructure, which in one embodiment is selected from the group consisting of expanded polytetrafluoroethylene (ePTFE) and expanded ultra high molecular weight polyethylene.

6946173, Sep 20, 2005

Mar 21, 2002

10/103274

Florencia Lim - Union City CA, US
Chi Le Long - San Jose CA, US
Charles D. Claude - Santa Clara CA, US
Jeong S. Lee - Diamond Bar CA, US
Srinivasan Sridharan - Morgan Hill CA, US
Fernando Gonzalez - Campbell CA, US
Edwin Wang - Tustin CA, US

Advanced Cardiovascular Systems, Inc. - Santa Clara CA

B32B001/08
A61M025/10
A61M029/00

428 352, 428 341, 428 357, 428 365, 428 368, 428 369, 428 3691, 604 9601, 60410305, 60410306, 60410308, 60410311, 60410313, 604264, 604523

A catheter balloon formed of a polymeric material such as expanded polytetrafluoroethylene (ePTFE) bonded to a second layer formed of a low tensile set polymer and/or impregnated with a low tensile set polymer. In a presently preferred embodiment, the low tensile set polymer is a silicone-polyurethane copolymer elastomer or a diene polymer elastomer. The low tensile set polymer has high strength, low modulus, high elongation, and low tensile set. The diene or silicone-polyurethane has a low tensile set, which facilitates deflation of the balloon to a low profile deflated configuration. One aspect of the invention provides improved attachment of the diene to the ePTFE. In one embodiment, the second layer is formed of a diene mixed with a bonding promoter such as a vulcanizing agent which is covalently bonded to the diene.

6949112, Sep 27, 2005

Jul 26, 2001

09/917024

Srinivasan Sridharan - Morgan Hill CA, US
Timoteo Tomas - Union City CA, US

Advanced Cardiovascular Systems, Inc. - Santa Clara CA

A61M029/00

606194

A medical device or component thereof, and particularly intracorporeal devices for therapeutic or diagnostic uses, formed at least in part of a copolymer having a hard block and a polylactone soft block. In a presently preferred embodiment, the hard block of the copolymer is a polyester, and more specifically, the copolymer comprises a di-block copolymer of poly(ethylene terephthalate) and polycaprolactone. The copolymer is suitable for forming a variety of medical devices or medical device components, and is preferably used to form a catheter balloon, such as a balloon for an angioplasty or stent delivery catheter. However, a variety of medical devices or medical device components can be formed of the copolymer, including stent covers, vascular grafts, and shaft components.