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Stanley I Letovsky, 6656 Canton Ave, Milton, MA 02186

Known as:
Stan I Letovsky Stanley Letousky
Related to:
Barbara J Holland-Eytan 82

Stanley Letovsky Phones & Addresses

56 Canton Ave, Milton, MA 02186    617-6969967    617-6969971   

Cambridge, MA   

Baltimore, MD   

Ithaca, NY   

New Haven, CT   

56 Canton Ave, Milton, MA 02186    617-6969967   

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Stanley I Letovsky

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Work

Position: Professional/Technical

Education

Degree: High school graduate or higher

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career opportunities, consulting offers, new ventures, expertise requests, business deals, reference requests, getting back in touch

Industries

Biotechnology
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Stanley Letovsky resumes & CV records

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Stanley Letovsky Photo 8

Vice President And Chief Informatics Officer At Synapdx Adjunct Professor At Boston University

Location:
Greater Boston Area
Industry:
Biotechnology
Experience:
SynapDx (Privately Held; Biotechnology industry): Vice President and Chief Informatics Officer,  (June 2010-Present) Boston University (Educational Institution; Higher Education industry): Adjunct Professor,  (2001-Present) Helicos BioSciences ...

Publications & IP owners

Us Patents

Methods For Detecting Fetal Nucleic Acids And Diagnosing Fetal Abnormalities

US Patent:
2013002, Jan 24, 2013
Filed:
Sep 14, 2012
Appl. No.:
13/619039
Inventors:
Stanley Lapidus - Bedford NH, US
John F. Thompson - Warwick RI, US
Doron Lipson - Chestnut Hill MA, US
Patrice Milos - Cranston RI, US
J. William Efcavitch - San Carlos CA, US
Stanley Letovsky - Milton MA, US
Assignee:
SEQUENOM, INC - San Diego CA
International Classification:
C12Q 1/68
B82Y 15/00
US Classification:
435 611, 977924
Abstract:
The invention generally relates to methods for detecting fetal nucleic acids and methods for diagnosing fetal abnormalities. In certain embodiments, the invention provides methods for determining whether fetal nucleic acid is present in a maternal sample including obtaining a maternal sample suspected to include fetal nucleic acids, and performing a sequencing reaction on the sample to determine presence of at least a portion of a Y chromosome in the sample, thereby determining that fetal nucleic acid is present in the sample. In other embodiments, the invention provides methods for quantitative or qualitative analysis to detect fetal nucleic acid in a maternal sample, regardless of the ability to detect the Y chromosome, particularly for samples including normal nucleic acids from a female fetus.

Methods For Determining A Gene Expression Profile And For Disease Diagnosis

US Patent:
2013003, Feb 7, 2013
Filed:
Aug 3, 2012
Appl. No.:
13/566167
Inventors:
Stanley Letovsky - Milton MA, US
Stanley Lapidus - Bedford NH, US
Assignee:
SYNAPDX CORP. - Southborough MA
International Classification:
C40B 30/04
C12Q 1/68
US Classification:
506 9, 435 612
Abstract:
The invention generally relates to methods for determining a gene expression profile and for disease diagnosis. In certain aspects, methods of the invention involve obtaining a sample including somatic cells, transforming the somatic cells into target cells, and determining an expression profile from the target cells.

Composite Assay For Developmental Disorders

US Patent:
2013017, Jul 11, 2013
Filed:
Jan 7, 2013
Appl. No.:
13/735435
Inventors:
Stanley N. Lapidus - Bedford NH, US
Stanley Letovsky - Milton MA, US
International Classification:
C12Q 1/68
US Classification:
506 9, 435 611
Abstract:
This invention relates generally to diagnosing developmental disorders by detecting two or more genetic characteristics from a nucleic acid extracted from a sample taken from a patient. The genetic characteristics detected include nucleic acid expression profiles, nucleic acid sequences, and nucleic acid copy numbers. The genetic characteristics may be detected using sequencing technology, array based technology, or both. At least two genetic characteristics are compared to respective controls. From the comparison a diagnostic profile of a developmental disorder for the patient is formed.

Methods For Detecting Fetal Nucleic Acids And Diagnosing Fetal Abnormalities

US Patent:
2013019, Aug 1, 2013
Filed:
Sep 13, 2012
Appl. No.:
13/614391
Inventors:
Stanley N. Lapidus - Bedford NH, US
John F. Thompson - Warwick RI, US
Doron Lipson - Chestnut Hill MA, US
Patrice Milos - Cranstono RI, US
J. William Efcavitch - San Carlos CA, US
Stanley Letovsky - Milton MA, US
Assignee:
SEQUENOM, INC - San Diego CA
International Classification:
C12Q 1/68
US Classification:
435 611
Abstract:
The invention generally relates to methods for detecting fetal nucleic acids and methods for diagnosing fetal abnormalities. In certain embodiments, the invention provides methods for determining whether fetal nucleic acid is present in a maternal sample including obtaining a maternal sample suspected to include fetal nucleic acids, and performing a sequencing reaction on the sample to determine presence of at least a portion of a Y chromosome in the sample, thereby determining that fetal nucleic acid is present in the sample. In other embodiments, the invention provides methods for quantitative or qualitative analysis to detect fetal nucleic acid in a maternal sample, regardless of the ability to detect the Y chromosome, particularly for samples including normal nucleic acids from a female fetus.

Systems And Methods For Normalizing Gene Expression Profiles Of Biological Samples Having A Mixed Cell Population

US Patent:
2014002, Jan 23, 2014
Filed:
May 1, 2013
Appl. No.:
13/875257
Inventors:
Stanley Letovsky - Milton MA, US
Assignee:
SYNAPDX CORPORATION - Lexington MA
International Classification:
C12Q 1/68
US Classification:
506 9, 435 612, 4352872, 506 39
Abstract:
The present disclosure generally provides methods for normalizing gene expression profiles against a cellular repertoire, i.e., the different proportions of various cell types in a sample containing multiple cell types. More specifically, the present disclosure encompasses a method for normalizing the gene expression profile against a mixed cell population.

Methods For Detecting Fetal Nucleic Acids And Diagnosing Fetal Abnormalities

US Patent:
2010021, Aug 26, 2010
Filed:
Mar 19, 2010
Appl. No.:
12/727824
Inventors:
STANLEY LAPIDUS - BEDFORD NH, US
JOHN F. THOMPSON - WARWICK RI, US
DORON LIPSON - CHESTNUT HILL MA, US
PATRICE MILOS - CRANSTONO RI, US
J. WILLIAM EFCAVITCH - SAN CARLOS CA, US
STANLEY LETOVSKY - MILTON MA, US
Assignee:
HELICOS BIOSCIENCES CORPORATION - CAMBRIDGE MA
International Classification:
C12Q 1/68
US Classification:
435 6
Abstract:
The invention generally relates to methods for detecting fetal nucleic acids and methods for diagnosing fetal abnormalities. In certain embodiments, the invention provides methods for determining whether fetal nucleic acid is present in a maternal sample including obtaining a maternal sample suspected to include fetal nucleic acids, and performing a sequencing reaction on the sample to determine presence of at least a portion of a Y chromosome in the sample, thereby determining that fetal nucleic acid is present in the sample. In other embodiments, the invention provides methods for quantitative or qualitative analysis to detect fetal nucleic acid in a maternal sample, regardless of the ability to detect the Y chromosome, particularly for samples including normal nucleic acids from a female fetus.

Methods For Detecting Fetal Nucleic Acids And Diagnosing Fetal Abnormalities

US Patent:
2010021, Aug 26, 2010
Filed:
Feb 19, 2010
Appl. No.:
12/709057
Inventors:
STANLEY LAPIDUS - BEDFORD NH, US
JOHN F. THOMPSON - WARWICK RI, US
DORON LIPSON - CHESTNUT HILL MA, US
PATRICE MILOS - CRANSTONO RI, US
J. WILLIAM EFCAVITCH - SAN CARLOS CA, US
STANLEY LETOVSKY - MILTON MA, US
Assignee:
Helicos BioSciences Corporation - Cambridge MA
International Classification:
C12Q 1/68
US Classification:
435 6
Abstract:
The invention generally relates to methods for detecting fetal nucleic acids and methods for diagnosing fetal abnormalities. In certain embodiments, the invention provides methods for determining whether fetal nucleic acid is present in a maternal sample including obtaining a maternal sample suspected to include fetal nucleic acids, and performing a sequencing reaction on the sample to determine presence of at least a portion of a Y chromosome in the sample, thereby determining that fetal nucleic acid is present in the sample. In other embodiments, the invention provides methods for quantitative or qualitative analysis to detect fetal nucleic acid in a maternal sample, regardless of the ability to detect the Y chromosome, particularly for samples including normal nucleic acids from a female fetus.

Methods For Reducing Guanine And Cytosine (Gc) Bias In Nucleotide Sequence Read Counts

US Patent:
2021030, Sep 30, 2021
Filed:
May 28, 2021
Appl. No.:
17/333569
Inventors:
- San Diego CA, US
John F. THOMPSON - Warwick RI, US
Doron LIPSON - Chestnut Hill MA, US
Patrice MILOS - Cranston RI, US
J. William EFCAVITCH - San Carlos CA, US
Stanley LETOVSKY - Milton MA, US
International Classification:
C12Q 1/6869
C12Q 1/6883
C12Q 1/6809
G16B 20/20
G16B 20/10
Abstract:
The invention generally relates to methods for analyzing nucleic acid sequence information. In some aspects, a sample is sequenced to obtain nucleic acid sequence information. In some aspects, an amount of GC bias in sequence information is determined. In some aspects, sequence information is corrected to account for the GC bias. In some aspects, corrected sequence information is analyzed.

Isbn (Books And Publications)

Bioinformatics: Databases And Systems

Author:
Stanley Letovsky
ISBN #:
0306469030

Possible Relatives

John M Letovsky  Stanley S Johnson  Stanley L Stancil  Stanley B Johnston  Stanley Q White  Stanley Jolly  Stanley W Jones  Stanley Stankiewicz  Stanley C Stanley  Stanley L Jordan 

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