Stephen Elledge resumes & CV records
Resumes
Stephen Elledge
Location:
United States
Stephen Bradley Elledge, 58Hitchcock, TX
Stephen Elledge Phones & Addresses
Hitchcock, TX
Richmond, TX
Houston, TX
7323 Quiet Glen Ct, Sugar Land, TX 77479
Galveston, TX
Social networks
Stephen Bradley Elledge
Linkedin
Mentions for Stephen Bradley Elledge
Publications & IP owners
Wikipedia
Stephen Elledge
Stephen J. Elledge Ph.D. is a Professor of Genetics at the Harvard Medical School. He earned his B.Sc. in chemistry from the University of Illinois at...
Us Patents
Method For Screening Of Dna Libraries And Generation Of Recombinant Dna Constructs
US Patent:
6376192, Apr 23, 2002
Filed:
Nov 28, 2000
Appl. No.:
09/724934
Inventors:
Stephen J. Elledge - Houston TX
Pumin Zhang - Pearland TX
Mamie Li - Houston TX
Pumin Zhang - Pearland TX
Mamie Li - Houston TX
Assignee:
Baylor College of Medicine - Houston TX
International Classification:
C12Q 168
US Classification:
435 6, 435477
Abstract:
A method of DNA library screening includes homologous recombination in utilizing lambda phage recombination functions. Inserting a positive selection marker such as antibiotic resistance into the target sequence by homologous recombination facilitates isolation of target sequences and requires only about 58-100 base pairs of total homology, thus allowing the use of synthetic fragments of DNA for targeting. DNA vector is designed for genomic library construction that features a novel genetic selection for inserts, automatic subcloning of isolated genomic clones and the presence of a negative selection marker adjacent to the genomic inserts to facilitate later gene targeting.
F-Box Genes And Proteins
US Patent:
6573094, Jun 3, 2003
Filed:
Oct 16, 1997
Appl. No.:
08/951621
Inventors:
Jeffrey Wade Harper - Sugarland TX
Stephen J. Elledge - Houston TX
Stephen J. Elledge - Houston TX
Assignee:
Baylor College of Medicine - Houston TX
International Classification:
C12N 500
US Classification:
435325, 536 231, 536 235, 4352523, 4353201
Abstract:
The present invention provides compositions and methods for gene identification, as well as drug discovery and assessment. In particular, the present invention provides components of an E3 complex involved in ubiquitination of cell cycle regulators and other proteins, as well as members of a class of proteins that directly function in recognition of ubiquitination targets. The present invention also provides sequences of multiple F-box proteins.
Rapid Subcloning Using Site-Specific Recombination
US Patent:
6828093, Dec 7, 2004
Filed:
Jul 24, 1998
Appl. No.:
09/122384
Inventors:
Stephen J. Elledge - Houston TX
Qinghua Liu - Houston TX
Qinghua Liu - Houston TX
Assignee:
Baylor College of Medicine - Houston TX
International Classification:
C12Q 168
US Classification:
435 6, 435462, 435476, 435477, 43525233, 435196
Abstract:
The present invention provides compositions, including vectors, and methods for the rapid subcloning of nucleic acid sequences in vivo and in vitro. In particular, the invention provides vectors used to contain a gene of interest that comprise a sequence-specific recombinase target site. These vectors are used to rapidly transfer the gene or genes of interest into any vector that contains a sequence-specific recombinase target site located downstream of a regulatory element so that the gene of interest may be regulated.
Methods And Compositions In Checkpoint Signaling
US Patent:
7101985, Sep 5, 2006
Filed:
Nov 20, 2002
Appl. No.:
10/300453
Inventors:
Stephen J. Elledge - Houston TX, US
David K. Cortez - Houston TX, US
Lee Zou - Houston TX, US
David K. Cortez - Houston TX, US
Lee Zou - Houston TX, US
Assignee:
Baylor College of Medicine - Houston TX
International Classification:
C07H 21/02
C12N 15/00
C12N 15/00
US Classification:
536 231, 4353201
Abstract:
The present invention is directed to compositions and methods regarding the signaling for the presence of DNA damage or replication stress and activating cell cycle checkpoints. Specifically, ATRIP was identified as an interactor with ATR, a member of the phosphatidylinositol kinase-related protein family that includes ATM and DNA-PK. In some embodiments, the present invention is directed to ATRIP and ATR acting as mutually dependent partners in cell cycle checkpoint signaling pathways.
In Vivo Gene Transfer
US Patent:
7338800, Mar 4, 2008
Filed:
Jan 16, 2003
Appl. No.:
10/345523
Inventors:
Stephen J. Elledge - Houston TX, US
Mamie Z. Li - Houston TX, US
Mamie Z. Li - Houston TX, US
Assignee:
Baylor College of Medicine - Houston TX
International Classification:
C12N 15/74
C12N 15/00
C12N 1/20
C12N 15/00
C12N 1/20
US Classification:
435471, 4353201, 4352523
Abstract:
The present invention is directed to an in vivo method of transferring DNA from a donor cell to a recipient cell. In a specific embodiment, the method comprises a highly efficient process of bacterial mating. In a preferred embodiment, selection for a recombinant plasmid against a parent host plasmid and donor plasmid is based on recircularization of the host plasmid by its recombination with a gene of interest such that it is now no longer cleaved by a restriction enzyme expressed in the recipient cell.
Mammalian Checkpoint Proteins Polypeptides And Encoding Sequences Thereof
US Patent:
RE40789, Jun 23, 2009
Filed:
Oct 9, 2002
Appl. No.:
10/267717
Inventors:
Stephen J. Elledge - Houston TX, US
Yolanda Sanchez - Cincinnati OH, US
Yolanda Sanchez - Cincinnati OH, US
Assignee:
Baylor College of Medicine - Houston TX
International Classification:
C12N 9/12
C12N 9/10
A61K 38/00
C07K 1/00
C12N 9/10
A61K 38/00
C07K 1/00
US Classification:
435194, 435193, 530324, 530326, 530350
Abstract:
The present invention relates to the isolation of gene sequences encoding mammalian cell cycle checkpoints, as well as the expression of the encoded proteins using recombinant DNA technology. The expressed proteins are used to generate specific antibodies and to inhibit the growth of cells. The human checkpoint gene sequences are used as a probe for a portion of the chromosome associated with tumors and other malignancies, as well as growth and/or development deficiencies.
Mammalian Checkpoint Genes And Proteins
US Patent:
2002015, Oct 24, 2002
Filed:
Dec 12, 2001
Appl. No.:
10/020038
Inventors:
Stephen Elledge - Houston TX, US
Yolanda Sanchez - Cincinnati OH, US
Yolanda Sanchez - Cincinnati OH, US
International Classification:
C07K016/40
US Classification:
530/389100
Abstract:
The present invention relates to the isolation of gene sequences encoding mammalian cell cycle checkpoints, as well as the expression of the encoded proteins using recombinant DNA technology. The expressed proteins are used to generate specific antibodies and to inhibit the growth of cells. The human checkpoint gene sequences are used as a probe for a portion of the chromosome associated with tumors and other malignancies, as well as growth and/or development deficiencies.
F-Box Proteins And Genes
US Patent:
2004016, Aug 26, 2004
Filed:
Mar 7, 2001
Appl. No.:
09/801348
Inventors:
Jeffrey Harper - Sugarland TX, US
Stephen Elledge - Houston TX, US
Jeffrey Winston - Thousand Oaks CA, US
Stephen Elledge - Houston TX, US
Jeffrey Winston - Thousand Oaks CA, US
International Classification:
G01N033/53
US Classification:
435/007100
Abstract:
The present invention provides compositions and methods for gene identification, as well as drug discovery and assessment. In particular, the present invention provides components of an E3 complex involved in ubiquitination of cell cycle regulators and other proteins, as well as members of a class of proteins that directly function in recognition of ubiquitination targets. The present invention also provides sequences of multiple F-box proteins.
Amazon
The Harvey Lectures: Series 97, 2001-2002 (Vol 97) By Harvey Society (2003-10-03)
Author:
Harvey Society;Patrick O. Brown;Constance L. Cepko;Stephen J. Elledge;A. J. Hudspeth;Peter S. Kim;Moshe Oren;Janet Rossant;Lee Zou
Publisher:
Wiley-Liss
Binding:
Hardcover
The Harvey Lectures: Series 97, 2001-2002 (Vol 97)
Author:
Harvey Society, Patrick O. Brown, Constance L. Cepko, Stephen J. Elledge, A. J. Hudspeth, Peter S. Kim, Moshe Oren, Janet Rossant, Lee Zou
Publisher:
Wiley-Liss
Binding:
Hardcover
Pages:
145
ISBN #:
0471476633
EAN Code:
9780471476634
The Harvey Society was founded in 1905 by thirteen New York City scientists and physicians with the purpose of forging a "closer relationship between the purely practical side of medicine and the results of laboratory investigation." The Society disseminates scientific knowledge in selected areas of...
Dna Repair, Mutagenesis, And Other Responses To Dna Damage (Cold Spring Harbor Perspectives In Biology)
Publisher:
Cold Spring Harbor Laboratory Press
Binding:
Hardcover
Pages:
445
ISBN #:
1936113546
EAN Code:
9781936113545
Cellular DNA is constantly bombarded with environmental and chemical assaults that damage its molecular structure. In addition, the normal process of DNA replication is prone to error and may introduce mutations that can be passed to daughter cells. If left unrepaired, these DNA lesions can have ser...
The Role Of Kip2 In Breast Cancer
Author:
Stephen J. Elledge
Publisher:
PN
Binding:
Paperback
Genomic Approaches For Detection And Treatment Of Breast Cancer
Author:
Stephen J. Elledge
Publisher:
PN
Binding:
Paperback
Development Of General Methods For Identification Of Genes Regulated By Oncogenic Stimuli Or Dna Damage
Author:
Stephen Elledge
Publisher:
PN
Binding:
Paperback
The Role Of Kip2 In Breast Cancer
Author:
Stephen J. Elledge
Publisher:
PN
Binding:
Paperback
The Role Of Chk2 In Breast Cancer
Author:
Stephen J. Elledge
Publisher:
PN
Binding:
Paperback
Isbn (Books And Publications)
The Harvey Lectures: Series 97, 2001-2002
Author:
Stephen J. Elledge
ISBN #:
0471476633
The Harvey Lectures: Series 98, 2002-2003
Author:
Stephen J. Elledge
ISBN #:
0471684791
Public records
Vehicle Records
Stephen Elledge
Address:
7323 Quiet Gln Dr, Sugar Land, TX 77479
VIN:
1J4RS4GT1AC112681
Make:
JEEP
Model:
GRAND CHEROKEE
Year:
2010
NOTICE: You may not use BackgroundCheck or the information it provides to make decisions about employment, credit, housing or any other purpose that would require Fair Credit Reporting Act (FCRA) compliance. BackgroundCheck is not a Consumer Reporting Agency (CRA) as defined by the FCRA and does not provide consumer reports.