Steven Craig Polomoscanik, 5649 Ponderosa Ave, Methuen, MA 01844
Steven Polomoscanik Phones & Addresses
49 Ponderosa Ave, Methuen, MA 01844 978-2580907
11 Harvard Dr, Bedford, MA 01730
95 Bridge St, Lexington, MA 02421
12 Lockwood Rd, Wilmington, MA 01887
Nashua, NH
Derry, NH
Lawrence, MA
49 Ponderosa Ave, Methuen, MA 01844
Mentions for Steven Craig Polomoscanik
Publications & IP owners
Us Patents
Aryl Boronate Functionalized Polymers For Treating Obesity
US Patent:
7041280, May 9, 2006
Filed:
Jun 27, 2002
Appl. No.:
10/187316
Inventors:
Stephen Randall Holmes-Farley - Arlington MA, US
Pradeep K. Dhal - Westford MA, US
Chad Cori Huval - Somerville MA, US
Xinhua Li - Newton MA, US
Steven Craig Polomoscanik - Bedford MA, US
Pradeep K. Dhal - Westford MA, US
Chad Cori Huval - Somerville MA, US
Xinhua Li - Newton MA, US
Steven Craig Polomoscanik - Bedford MA, US
Assignee:
Genzyme Corporation - Cambridge MA
International Classification:
A61K 31/80
US Classification:
424 7817, 424 7818, 424 7826, 525337, 528 4, 528 8, 528394
Abstract:
Disclosed are polymers comprising one or more phenyl boronate ester, boronamide or boronate thioester groups. The phenyl boronate ester, boronamide and boronate thioester groups are represented by one of the following structural formulas:Ar in Structural Formulas (I) and (II) is substituted or unsubstituted; and each Z is —O—, —NH— or —S— and is independently selected. Pharmaceutically acceptable salts of the polymer are also included. The aryl boronate ester, boronamide or boronate thioester can be cleaved to release the corresponding aryl boronic acid. Also disclosed are pharmaceutical compositions comprising the polymers of the present invention and a pharmaceutically acceptable carrier or diluent; and methods of treating a subject for obesity with the polymers of the present invention.
Aryl Boronate Functionalized Polymers For Treating Obesity
US Patent:
2006012, Jun 15, 2006
Filed:
Jan 27, 2006
Appl. No.:
11/342129
Inventors:
Stephen Holmes-Farley - Arlington MA, US
W. Mandeville - Lynnfield MA, US
Pradeep Dhal - Westford MA, US
Chad Huval - Somerville MA, US
Xinhua Li - Waban MA, US
Steven Polomoscanik - Bedford MA, US
W. Mandeville - Lynnfield MA, US
Pradeep Dhal - Westford MA, US
Chad Huval - Somerville MA, US
Xinhua Li - Waban MA, US
Steven Polomoscanik - Bedford MA, US
Assignee:
Genzyme Corporation - Cambridge MA
International Classification:
A61K 31/69
C08G 79/08
A01N 55/08
C08G 79/08
A01N 55/08
US Classification:
514064000, 528004000, 528007000, 528008000
Abstract:
Disclosed are polymers comprising one or more phenyl boronate ester, boronamide or boronate thioester groups. The phenyl boronate ester, boronamide and boronate thioester groups are represented by one of the following structural formulas: Ar in Structural Formulas (I) and (II) is substituted or unsubstituted; and each Z is —O—, —NH— or —S— and is independently selected. Pharmaceutically acceptable salts of the polymer are also included. The aryl boronate ester, boronamide or boronate thioester can be cleaved to release the corresponding aryl boronic acid. Also disclosed are pharmaceutical compositions comprising the polymers of the present invention and a pharmaceutically acceptable carrier or diluent; and methods of treating a subject for obesity with the polymers of the present invention.
Pharmaceutical Compositions
US Patent:
2009015, Jun 18, 2009
Filed:
Dec 12, 2008
Appl. No.:
12/314554
Inventors:
Stephen Randall Holmes-Farley - Arlington MA, US
David J. Harris - Lexington MA, US
Steven C. Polomoscanik - Bedford MA, US
Adnan Salameh - Waltham MA, US
Bruce Shutts - Bolton MA, US
Richard Silva - Needham MA, US
Pradeep K. Dhal - Westford MA, US
Lynne Sole - Billerica MA, US
David J. Harris - Lexington MA, US
Steven C. Polomoscanik - Bedford MA, US
Adnan Salameh - Waltham MA, US
Bruce Shutts - Bolton MA, US
Richard Silva - Needham MA, US
Pradeep K. Dhal - Westford MA, US
Lynne Sole - Billerica MA, US
Assignee:
Genzyme Corporation - Cambridge MA
International Classification:
A61K 9/14
A61K 31/785
A61P 1/00
A61K 31/785
A61P 1/00
US Classification:
424489, 424 7808
Abstract:
The present invention relates to crosslinked polyamine particles and/or pharmaceutical compositions comprising, at least in part, crosslinked polyamine particles and aggregates of such particles (including cured aggregates of crosslinked polyamine particles). The compositions may be in the form of tablets comprising, for example, particles larger than 500 μm, and used for treating patients, for example, patients with hyperphosphatemia.
Amine Polymer Compositions
US Patent:
2010012, May 27, 2010
Filed:
Feb 20, 2008
Appl. No.:
12/449729
Inventors:
Pradeep K. Dhal - Westford MA, US
Stephen Randall Holmes-Farley - Arlington MA, US
Chad C. Huval - Somerville MA, US
Steven C. Polomoscanik - Bedford MA, US
Stephen Randall Holmes-Farley - Arlington MA, US
Chad C. Huval - Somerville MA, US
Steven C. Polomoscanik - Bedford MA, US
International Classification:
A61K 31/785
A61P 13/12
A61P 13/12
US Classification:
424 7812
Abstract:
A pharmaceutical composition for treating hyperphosphatemia can include polymers derived from multi-amine monomers and multifunctional monomers, where the multifunctional monomer includes more than one electrophilic group.
Amido-Amine Dendrimer Compositions
US Patent:
2010016, Jul 1, 2010
Filed:
Apr 25, 2008
Appl. No.:
12/451060
Inventors:
Pradeep K. Dhal - Westford MA, US
Stephen Randall Holmes-Farley - Arlington MA, US
Chad C. Huval - Somerville MA, US
Steven C. Polomoscanik - Bedford MA, US
Stephen Randall Holmes-Farley - Arlington MA, US
Chad C. Huval - Somerville MA, US
Steven C. Polomoscanik - Bedford MA, US
International Classification:
A61K 31/765
A61P 13/12
A61P 13/12
US Classification:
424 7837
Abstract:
Amide compounds, amide polymers and compositions, including amide compounds and amide polymers, may be used to bind target ions, such as phosphorous-containing compounds in the gastrointestinal tract of animals. In some cases, the amide polymers may be amido-amine dendrimers that may be formed via a series of iterative reactions.
Sulfone Polymer Compositions
US Patent:
2010019, Aug 5, 2010
Filed:
Mar 5, 2008
Appl. No.:
12/449974
Inventors:
Pradeep K. Dhal - Westford MA, US
Stephen Randall Holmes-Farley - Arlington VA, US
Chad C. Huval - Somerville MA, US
Steven C. Polomoscanik - Bedford MA, US
Stephen Randall Holmes-Farley - Arlington VA, US
Chad C. Huval - Somerville MA, US
Steven C. Polomoscanik - Bedford MA, US
International Classification:
A61K 31/795
A61P 3/00
A61P 3/00
US Classification:
424 7808
Abstract:
Sulfone-containing copolymers and copolymer networks and compositions including sulfone-containing copolymers and copolymer networks may be used to bind target ions, such as phosphorous-containing compounds in the gastrointestinal tract of animals. In some cases, sulfone-containing copolymers and copolymer networks may be derived from a multi-amine monomer and a multifunctional sulfonyl-containing monomer comprising two or more amine-reactive groups.
Sulfone Polymer Compositions
US Patent:
2013026, Oct 10, 2013
Filed:
Jan 28, 2013
Appl. No.:
13/751822
Inventors:
Stephen Randall HOLMES-FARLEY - Framingham MA, US
Chad HUVAL - Framingham MA, US
Steven C. POLOMOSCANIK - Framingham MA, US
Chad HUVAL - Framingham MA, US
Steven C. POLOMOSCANIK - Framingham MA, US
International Classification:
C08G 75/20
US Classification:
424 7817, 424 7837, 424 7836
Abstract:
Sulfone-containing copolymers and copolymer networks and compositions including sulfone-containing copolymers and copolymer networks may be used to bind target ions, such as phosphorous-containing compounds in the gastrointestinal tract of animals. In some cases, sulfone-containing copolymers and copolymer networks may be derived from a multi-amine-monomer and a multifunctional sulfonyl-containing monomer comprising two or more amine-reactive groups.
Polymers Containing Spirobicyclic Ammonium Moieties As Bile Acid Sequestrants
US Patent:
6271264, Aug 7, 2001
Filed:
Dec 1, 1998
Appl. No.:
9/203319
Inventors:
Pradeep K. Dhal - Acton MA
Steven C. Polomoscanik - Lexington MA
Steven C. Polomoscanik - Lexington MA
Assignee:
GelTex Pharmaceuticals, Inc. - Waltham MA
International Classification:
A61K 3114
A61K 31045
A61K 3113
A61K 3133
A61K 3174
A61K 31045
A61K 3113
A61K 3133
A61K 3174
US Classification:
514642
Abstract:
The present invention relates to a method for sequestering bile acids in a patient and to particular polymers for use in the method. The method comprises administering a therapeutically effective amount of a spirobicyclic ammonium moiety-containing polymer composition to a mammal, such as a human, whereby bile acids are sequestered. The polymers of the invention comprise spirobicyclic ammonium moieties and optionally, further comprise a hydrophobic substituent, a quaternary ammonium-containing substituent or a combination thereof.
NOTICE: You may not use BackgroundCheck or the information it provides to make decisions about employment, credit, housing or any other purpose that would require Fair Credit Reporting Act (FCRA) compliance. BackgroundCheck is not a Consumer Reporting Agency (CRA) as defined by the FCRA and does not provide consumer reports.