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Jonathan Scott Brown, 62Bushwood, MD

Jonathan Brown Phones & Addresses

Bushwood, MD   

1620 E Broad St APT 1106, Columbus, OH 43203    425-2283025   

Alexandria, VA   

2807 S Norman St, Seattle, WA 98144   

Renton, WA   

Kiona, WA   

Spokane, WA   

Mentions for Jonathan Scott Brown

Career records & work history

Real Estate Brokers

Jonathan Brown Photo 1

State Of Virginia Real Estate Salespersons License

Specialties:
Buyer's Agent, Listing Agent, General Contracting, Interior Design
Work:
Samson Properties (Chantilly)
14526 Lee Rd #100, Chantilly, VA 20151
202-5916837 (Office)
Licenses:
0225204730 (State of Virginia Real Estate Salespersons License)
Languages:
Japanese
French
Links:
Site
Blog
Facebook
Twitter
LinkedIn

Lawyers & Attorneys

Jonathan Brown Photo 2

Jonathan G Brown - Lawyer

Licenses:
Dist. of Columbia - Active 2008
Jonathan Brown Photo 3

Jonathan Brown - Lawyer

Office:
DLA Piper (Canada) LLP
Specialties:
Corporate Services, Securities and Corporate Finance, Capital Markets
ISLN:
919623116
Admitted:
2007
University:
University of British Columbia, B.A., 2002
Law School:
University of Saskatchewan, LL.B., 2006
Jonathan Brown Photo 4

Jonathan Brown - Lawyer

Office:
Burr & Forman LLP
Specialties:
Corporate Litigation, Probate & Trust, Appellate Practice, Banking, Bankruptcy Litigation, Business, Civil Litigation, Commercial, Commercial Litigation, Consumer Finance Litigation & Compliance, Contracts, Creditors' Rights & Bankruptcy, Dispute Resolution, Insurance Litigation & Coverage, Real Estate, Real Property, Commercial, Arbitration, Dispute Resolution, Real Estate
ISLN:
921225117
Admitted:
2010
University:
Emory University, B.A., 2004; University of Miami, M.B.A., 2008
Law School:
University of Miami School of Law, J.D., 2009
Jonathan Brown Photo 5

Jonathan Brown - Lawyer

ISLN:
1000663812
Admitted:
2011
Jonathan Brown Photo 6

Jonathan Brown - Lawyer

Specialties:
Intellectual Property, Litigation, Intellectual Property Law, Patent Application, Licensing, Patent Application
ISLN:
916480323
Admitted:
2001
University:
Stanford University, A.B., 1997; Stanford University, B.S., 1997
Law School:
University of California, Berkeley, Boalt Hall School of Law, J.D., 2001
Jonathan Brown Photo 7

Jonathan Brown - Lawyer

Office:
Hill Dickinson LLP
ISLN:
908747656
Jonathan Brown Photo 8

Jonathan Garrett Brown, Vienna VA - Lawyer

Office:
304 Patrick Street S.w., Vienna, VA
ISLN:
915071959
Admitted:
1998
University:
University of Georgia, B.S.
Law School:
University of Georgia, J.D.

Medicine Doctors

Jonathan Brown Photo 9

Jonathan R Brown, Issaquah WA - MA (Medicare Advantage)

Specialties:
Counseling
Address:
22525 Se 64Th Pl Suite 264, Issaquah, WA 98027
425-3954707 (Phone)
Languages:
English

Jonathan M. Brown

Specialties:
Otolaryngology, Facial Plastic Surgery
Work:
Mohave Ear Nose & Throat
2755 Silver Crk Rd STE 111, Bullhead City, AZ 86442
928-4441491 (phone) 928-4441497 (fax)
Education:
Medical School
Western Univ of Health Sciences College of Osteopathic Medicine of the Pacific
Graduated: 1998
Procedures:
Hearing Evaluation, Myringotomy and Tympanotomy, Rhinoplasty, Sinus Surgery, Tonsillectomy or Adenoidectomy, Tympanoplasty
Conditions:
Acne, Acute Bronchitis, Acute Pharyngitis, Acute Sinusitis, Acute Upper Respiratory Tract Infections, Allergic Rhinitis, Atopic Dermatitis, Bell's Palsy, Benign Paroxysmal Positional Vertigo, Bronchial Asthma, Burns, Candidiasis, Chronic Sinusitis, Deviated Nasal Septum, Fractures, Dislocations, Derangement, and Sprains, Gastroesophageal Reflux Disease (GERD), Gastrointestinal Hemorrhage, Hearing Loss, Hypothyroidism, Infectious Mononucleosis, Laryngeal Cancer, Non-Toxic Goiter, Obstructive Sleep Apnea, Otitis Media, Skin and Subcutaneous Infections, Tempromandibular Joint Disorders (TMJ), Thyroiditis, Varicose Veins
Languages:
English, Spanish
Description:
Dr. Brown graduated from the Western Univ of Health Sciences College of Osteopathic Medicine of the Pacific in 1998. He works in Bullhead City, AZ and specializes in Otolaryngology and Facial Plastic Surgery. Dr. Brown is affiliated with Western Arizona Regional Medical Center.

Jonathan R. Brown

Specialties:
Internal Medicine
Work:
NorthShore Medical GroupNorthshore Medical Group
49 S Waukegan Rd, Deerfield, IL 60015
847-9454575 (phone) 847-9454593 (fax)
Site
Education:
Medical School
Northwestern University Feinberg School of Medicine
Graduated: 1994
Procedures:
Destruction of Benign/Premalignant Skin Lesions, Electrocardiogram (EKG or ECG), Pulmonary Function Tests, Skin Tags Removal, Vaccine Administration
Conditions:
Abnormal Vaginal Bleeding, Acne, Acute Conjunctivitis, Acute Pharyngitis, Acute Sinusitis, Acute Upper Respiratory Tract Infections, Alopecia Areata, Attention Deficit Disorder (ADD), Benign Paroxysmal Positional Vertigo, Constipation, Contact Dermatitis, Dermatitis, Erectile Dysfunction (ED), Gout, Hearing Loss, Hemorrhoids, Herpes Zoster, Inflammatory Bowel Disease (IBD), Inguinal Hernia, Intervertebral Disc Degeneration, Migraine Headache, Obstructive Sleep Apnea, Osteoporosis, Overweight and Obesity, Plantar Warts, Sciatica, Abdominal Hernia, Acute Bronchitis, Acute Myocardial Infarction (AMI), Acute Pancreatitis, Alcohol Dependence, Anal or Rectal Abscess, Anemia, Anxiety Phobic Disorders, Appendicitis, Atrial Fibrillation and Atrial Flutter, Benign Prostatic Hypertrophy, Bipolar Disorder, Bronchial Asthma, Burns, Calculus of the Urinary System, Cardiac Arrhythmia, Cardiomyopathy, Carpel Tunnel Syndrome, Cataract, Chickenpox, Cholelethiasis or Cholecystitis, Chronic Bronchitis, Chronic Renal Disease, Conduction Disorders, Dehydration, Depressive Disorders, Diabetes Mellitus (DM), Disorders of Lipoid Metabolism, Diverticulitis, Emphysema, Epilepsy, Esophagitis, Female Infertility, Fractures, Dislocations, Derangement, and Sprains, Gastroesophageal Reflux Disease (GERD), Gastrointestinal Hemorrhage, Gingival and Periodontal Diseases, Glaucoma, Hallux Valgus, Herpes Genitalis, Herpes Simplex, Hypertension (HTN), Hyperthyroidism, Hypothyroidism, Infectious Liver Disease, Insomnia, Internal Derangement of Knee Cartilage, Intestinal Obstruction, Irritable Bowel Syndrome (IBS), Ischemic Heart Disease, Ischemic Stroke, Lateral Epicondylitis, Macular Degeneration, Male Infertility, Malignant Neoplasm of Female Breast, Melanoma, Menopausal and Postmenopausal Disorders, Mitral Valvular Disease, Non-Toxic Goiter, Osteoarthritis, Otitis Media, Parkinson's Disease, Peripheral Nerve Disorders, Pneumonia, Prostatitis, Psoriasis, Pulmonary Embolism, Restless Leg Syndrome, Retinal Detachments, Rheumatoid Arthritis, Rosacea, Rotator Cuff Syndrome and Allied Disorders, Sexually Transmitted Diseases (STDs), Skin and Subcutaneous Infections, Skin Cancer, Spinal Stenosis, Substance Abuse and/or Dependency, Tempromandibular Joint Disorders (TMJ), Thyroid Cancer, Tinea Pedis, Urinary Incontinence, Varicose Veins, Venous Embolism and Thrombosis, Ventral Hernia, Vitamin D Deficiency
Languages:
Arabic, English, Russian, Spanish
Description:
Dr. Brown graduated from the Northwestern University Feinberg School of Medicine in 1994. He works in Deerfield, IL and specializes in Internal Medicine. Dr. Brown is affiliated with Glenbrook Hospital, Highland Park Hospital, Northshore University Health System Evanston Hospital and Northshore University HealthSystem.

Jonathan Brown

Specialties:
Cardiovascular Disease
Work:
Carolina Cardiology Associates
196 Cardiology Dr, Rock Hill, SC 29732
803-3245135 (phone) 803-3248161 (fax)
Site
Languages:
English
Description:
Mr. Brown works in Rock Hill, SC and specializes in Cardiovascular Disease. Mr. Brown is affiliated with Piedmont Medical Center.
Jonathan Brown Photo 10

Jonathan Ray Brown, Seattle WA

Specialties:
Psychologist
Address:
1600 E Olive St, Seattle, WA 98122
22525 Se 64Th Pl, Issaquah, WA 98027

License Records

Jonathan Everett Brown

Licenses:
License #: C006484 - Active
Category: Social Work
Issued Date: Aug 7, 2009
Expiration Date: Jun 30, 2017
Type: Clinical Social Worker

Jonathan R Brown

Licenses:
License #: 54.18.4614 - Expired
Issued Date: Apr 20, 2005
Expiration Date: Jan 2, 2017
Type: Fire Protection Individual
License #: 54.18.4614/1 - Active
Category: Fire Alarms/Detection
Issued Date: Jan 3, 2005

Jonathan Taylor Brown

Licenses:
License #: PST - Expired
Type: Pharmacist

Jonathan L Brown

Address:
3179 Hogan Way, Columbus, OH
Licenses:
License #: SAL.2009003858 - Active
Issued Date: Nov 9, 2009
Renew Date: Nov 9, 2009
Effective Date: Apr 21, 2019
Expiration Date: Apr 21, 2019
Type: Real Estate Salesperson

Jonathan R Brown

Licenses:
License #: 21886 - Active
Category: Architect
Issued Date: Feb 4, 2010
Expiration Date: May 31, 2017
Organization:
Firm Not Published

Jonathan Brown

Licenses:
License #: 974028 - Expired
Category: Swimming Pool Operator
Issued Date: Aug 1, 2001
Effective Date: Jun 30, 2005
Expiration Date: Jun 15, 2005
Type: Swimming Pool Operator

Jonathan Brown resumes & CV records

Resumes

Jonathan Brown Photo 36

Jonathan Brown - Richmond, VA

Work:
IData Incorporated Jul 2008 to 2000
Marketing and Sales Assistant,
Alleyne A.M.E. Zion Church Jun 2008 to Aug 2011
Administrative Assistant
Giant Food Jun 2006 to Apr 2008
Cashier/Produce Clerk
Education:
Virginia Commonwealth University - Richmond, VA 2011 to 2015
Bachelor of Science in Supply Chain Management and Analytics
Northern Virginia Community College - Annandale, VA Aug 2009 to May 2011
Associate of Science in Accounting
Jonathan Brown Photo 37

Jonathan Brown - Twinsburg, OH

Work:
United American Security 2011 to 2000
Security Officer
The Geek Computer service repair 2010 to 2000
Repair Tech and Business owner
Metro Cleveland Security - Euclid, OH 2010 to 2011
Security Officer
Universal Electronics Inc - Twinsburg, OH 2009 to 2010
Call Center Technician
WILBRO Productions - Columbus, OH 2003 to 2010
Shop Apprentice
U.S. Security Associates - Columbus, OH 2009 to 2009
Security officer
Ohio Retail Security - Columbus, OH 2008 to 2009
Security officer
Ohio Retail Security - Whitehall, OH 2008 to 2008
Power tool sales
Sears Holding Company - Columbus, OH 2008 to 2008
Loss Prevention Agent
Speedway Convenient Store - Grandview, OH 2007 to 2008
Food steward
WILBRO Productions - Columbus, OH 2005 to 2007
Columbus Area Supervisor
Moling & Associates Inc - Columbus, OH 2001 to 2005
Field Supervisor
Smith's Security - Columbus, OH 2000 to 2001
Security/Patrol Officer
Jonathan Brown Photo 38

Jonathan Brown - Atlanta, GA

Work:
J.D. Fletcher & Associates Accounting Firm Aug 2012 to Jan 2013
Marketing Representative
Day 1 Productions Inc - College Park, MD Jun 2012 to Aug 2012
Sales & Marketing Rep/ Booking Agent
Vector - Upper Marlboro, MD Jun 2010 to Aug 2010
Sales Representative - Vector Sales & Marketing
Education:
Clark Atlanta University Aug 2010 to 2000
Bachelor of Arts in Business Administration
Skills:
Writing/communications Management Skills Marketing Sales Conversational Spanish Verbal Communications (Persuasive & Rebuttal) Microsoft Office (Excel, Word, PowerPoint)
Jonathan Brown Photo 39

Jonathan Brown - Taylorsville, UT

Work:
Utah Army National Guard Jan 2012 to 2000
Distribution and Maintenance Platoon Leader
University of Utah Army ROTC - Salt Lake City, UT 2012 to Jan 2012
Cadet
Washington Army National Guard - Seattle, WA Oct 2009 to Dec 2011
Medical Laboratory Technician
Education:
University of Utah - Salt Lake City, UT 2015
Bachelor of Science in Emergency Medicine Management
Army Medical Center and School 2011
Associate of Science in Medical Laboratory Sciences
Jonathan Brown Photo 40

Jonathan Brown - Magnolia, DE

Work:
EMCOR Government Services - Arlington, VA Mar 2013 to May 2013
Project Manager
Rand Enterprises Inc - Newport News, VA Oct 2011 to Mar 2013
Construction Quality Control Manager
US Air Force - Dover AFB, DE Sep 2010 to Oct 2011
Construction Manager, Master Sergeant
US Air Force Sep 2009 to Sep 2010
Mechanical Systems Superintendent, Master Sergeant (E-7)
US Air Force Mar 2009 to Aug 2009
Infrastructure Systems Superintendent, Master Sergeant (E-7)
HVAC/R Shop Aug 2002 to Mar 2008
Non-Commissioned Officer in Charge
Education:
Senior Non-commissioned Officer Academy Mar 2008
AAS in Mechanical and Electrical Technology
Jonathan Brown Photo 41

Jonathan Brown - Washington, DC

Work:
Guest Services Apr 2008 to 2000
Guide patrons
Parking Attendance - Washington, DC Mar 2006 to Apr 2011
Atlantic Valet
Education:
Eastern High School Washington - Washington, DC Jun 1982
High School Diploma
Jonathan Brown Photo 42

Jonathan Brown - Hyattsville, MD

Work:
Food & Friends - Washington, DC Aug 2011 to Apr 2013
Director of Program Services
Food Bank of Central & Eastern North Carolina - Raleigh, NC Jul 2003 to Aug 2011
Outreach, Evaluations and Programs Manager
Food Bank of Central & Eastern North Carolina - Raleigh, NC Jul 2002 to Jul 2003
Program Coordinator
NC Department of Corrections - Community Service Work Program - Durham, NC Jun 2001 to Jul 2002
Community Service District Coordinator
Education:
University of North Carolina - Greensboro, NC May 1997
Bachelor of Arts in Political Science
University of North Carolina at Greensboro - Greensboro, NC Jan 2001
Master of Public Administration
Skills:
Program & Project Implementation, Management & Analysis; Strategic Planning, Financial Planning, Budget Development & Management, Public Policy & Advocacy, Community Outreach, Coalition Building, Grant Writing, Facilitative Leadership, Volunteer Management, Non-profit Management, Public Speaking, American Sign Language
Jonathan Brown Photo 43

Jonathan Brown - Arlington, VA

Work:
Young Men's Christian Association May 2012 to 2000
Personal Trainer
Personal trainer - Alexandria, VA 2000 to 2012
Skills:
Customer Service Certified, Commission Based Background, Sales.

Publications & IP owners

Wikipedia

Jonathan Brown Photo 44

Jathan Brown (Australian Rules Footballer) The Free ...

Jonathan Brown (born 29 October 1981) is an Australian rules footballer playing for the Brisbane Lions in the Australian Football League. Widely regarded as ...
Jonathan Brown Photo 45

Jathan Brown

Jonathan Brown may refer to: Jon Brown (born 1971), British-Canadian runner, who went on to represent Canada; Jonathan Brown (born 1939), American ...

Us Patents

13C,15N ,2H Labeled Proteins For Nmr Structure Determinations And Their Preparation

US Patent:
6335196, Jan 1, 2002
Filed:
Mar 15, 2000
Appl. No.:
09/486837
Inventors:
Jonathan Miles Brown - Silver Spring MD
Philip Edward Coughlin - Wilmington DE
Steven William Homans - Dundee, GB
Charles Tobias Weller - Fife, GB
Assignee:
Martek Biosciences Corp. - Columbia MD
International Classification:
C12N 502
US Classification:
435404, 435243, 4352536, 4352568
Abstract:
This invention is concerned with determining the three-dimensional structure of biological macromolecules such as proteins. In particular, it is concerned with methods for rapidly determining protein structure by NMR, by providing methods for simplifying NMR spectra using labeled proteins prepared from specifically isotopically labeled amino acids having at least two isotopes of 13C, 15N and 2H in the backbone, and methods for making these labeled proteins, e. g. , by cultivation of a microbial culture containing said labeled amino acids.

13C, 15N, 2H Labeled Proteins For Nmr Structure Determinations And Their Preparation

US Patent:
6340578, Jan 22, 2002
Filed:
Jul 10, 2000
Appl. No.:
09/613571
Inventors:
Jonathan Miles Brown - Silver Spring MD
Philip Edward Coughlin - Wilmington DE
Steven William Homans - Dundee, GB
Charles Tobias Weller - Fife, GB
Assignee:
Martek Biosciences Corporation - Columbia MD
International Classification:
C12P 2100
US Classification:
435 711, 530300, 530350
Abstract:
This invention is concerned with determining the three-dimensional structure of biological macromolecules such as proteins. In particular, it is concerned with methods for rapidly determining protein structure by NMR, by providing methods for simplifying NMR spectra using labeled proteins prepared from specifically isotopically labeled amino acids having at least two isotopes of 13C, 15N and 2H in the backbone, and methods for making these labeled proteins, e. g. , by cultivation of a microbial culture containing said labeled amino acids.

13C, 15N, 2H Labeled Proteins For Nmr Structure Determinations And Their Preparation

US Patent:
6376253, Apr 23, 2002
Filed:
Jul 10, 2000
Appl. No.:
09/613570
Inventors:
Jonathan Miles Brown - Silver Spring MD
Philip Edward Coughlin - Wilmington DE
Steven William Homans - Dundee, GB
Charles Tobias Weller - Fife, GB
Assignee:
Martek Biosciences Corporation - Columbia MD
International Classification:
G01N 3300
US Classification:
436 86, 436173
Abstract:
The invention is concerned with determining the three-dimensional structure of biological macromolecules such as proteins. In particular, it is concerned with methods for rapidly determining protein structure by NMR, by providing methods for simplifying NMR spectra using labeled proteins prepared from specifically isotopically labeled amino acids having at least two isotopes of 13C, 15N and 2H in the backbone, and methods for making these labeled proteins, e. g. , by cultivation of a microbial culture containing said labeled amino acids.

Method For Obtaining Dynamic And Structural Data Pertaining To Proteins And Protein/Ligand Complexes

US Patent:
2006015, Jul 13, 2006
Filed:
Jun 10, 2003
Appl. No.:
10/517380
Inventors:
Jonathan Brown - Silver Spring MD, US
Steven Homans - Leeds, GB
Minn-Chang Cheng - Clarksville MD, US
Michael Chaykovsky - Columbia MD, US
Jenny Murray - Gaitersburg MD, US
Assignee:
ProSpect Pharma - Columbia MD
International Classification:
C12Q 1/37
C12Q 1/04
G01N 33/00
C07C 229/02
US Classification:
435023000, 435034000, 562557000, 436086000
Abstract:
This invention provides an NMR method for obtaining both entropic and enthalpic data on proteins and protein/ligand complexes which can be used to obtain accurate structural and dynamic data of proteins and protein complexes having a wide range of molecular weights. An embodiment of the invention provides proteins which contain at least one bond vector whose dynamics are to be measured and which is surrounded by NMR inactive nuclei, and amino acids for synthesis of the proteins via chemical means or biological expression. The NMR methods using specifically labeled proteins for analysis result in maximization of the sensitivity and resolution of the NMR experiments, and minimization of the loss of signal due to diffusion.

Side Chain Deuterated Amino Acids Methods Of Use

US Patent:
2007027, Nov 29, 2007
Filed:
Oct 7, 2004
Appl. No.:
10/574967
Inventors:
Jonathan Brown - Silver Spring MD, US
Steven Homans - Bramhope, GB
Michael Chaykovsky - Columbia MD, US
Jenny Murray - Gaithersburg MD, US
Assignee:
ProSpect Pharma - Columbia MD
International Classification:
G01N 33/53
C07C 211/01
G01N 24/08
C12P 21/06
US Classification:
435071100, 435243000, 436086000, 530300000, 562553000
Abstract:
Protein structural determination using NMR techniques is improved through use of proteins in which one or more amino acids in the peptidic sequence are isotopically enriched in the sidechain with 2H and are isotopically enriched on the backbone with 13C, 15N, 2H or any combination thereof. This invention provides amino acids isotopically enriched as above, which can be used to synthesize isotopically labeled proteins and peptides for protein structural determinations by NMR, and methods for their synthesis. Other embodiments of the invention include peptidic molecules, media for peptidic molecule expression, methods of making isotopically labeled peptidic molecules and methods of determining structural information of a peptidic molecule.

Side Chain Deuterated Amino Acids And Methods Of Use

US Patent:
2011030, Dec 22, 2011
Filed:
Mar 15, 2011
Appl. No.:
13/048583
Inventors:
Jonathan Miles Brown - Silver Spring MD, US
Steven W. Homans - Bramhope, GB
Michael Chaykovsky - Columbia MD, US
Jenny Hong Murray - Gaithersburg MD, US
Assignee:
ProSpect Pharma - Baltimore MD
International Classification:
G01R 33/44
C12N 9/10
C12P 13/04
C07C 229/08
US Classification:
324309, 562575, 435193, 435106
Abstract:
Protein structural determination using NMR techniques is improved through use of proteins in which one or more amino acids in the peptidic sequence are isotopically enriched in the sidechain with H and are isotopically enriched on the backbone with C, N, H or any combination thereof. This invention provides amino acids isotopically enriched as above, which can be used to synthesize isotopically labeled proteins and peptides for protein structural determinations by NMR, and methods for their synthesis. Other embodiments of the invention include peptidic molecules, media for peptidic molecule expression, methods of making isotopically labeled peptidic molecules and methods of determining structural information of a peptidic molecule.

Peptidic Molecules Which Have Been Isotopically Substituted With .Sup.13 C, .Sup.15 N And .Sup.2 H In The Backbone But Not In The Sidechains

US Patent:
6111066, Aug 29, 2000
Filed:
Sep 2, 1997
Appl. No.:
8/921554
Inventors:
Frank Elbert Anderson - Bel-Air MD
Jonathan Miles Brown - Silver Spring MD
Philip Edward Coughlin - Wilmington DE
Steven William Homans - Dundee, GB
Charles Tobias Weller - Fife, GB
Assignee:
Martek Biosciences Corporation - Columbia MD
International Classification:
C07K 200
C07K 113
US Classification:
530300
Abstract:
Peptidic molecules suitable for three dimensional NMR structure determination are provided which have been substituted with. sup. 13 C and/or. sup. 15 N in the backbone and/or at the. alpha. -carbon with. sup. 2 H but not otherwise in the sidechains of the amino acid residues. One or more amino acids, amino acid species or substantially all of the amino acid residues of the molecule may be so substituted. A method of making the substituted peptidic molecules substituted in this manner is provided.

Defined Multi-Conjugates Oligonucleotides

US Patent:
2022029, Sep 15, 2022
Filed:
May 18, 2022
Appl. No.:
17/747924
Inventors:
- Chevy Chase MA, US
Hans-Peter Vornlocher - Kulmbach, DE
Jonathan Miles Brown - Silver Spring MD, US
James Everett Dahlman - Atlanta GA, US
Kristin K.H. Neuman - Larchmont NY, US
International Classification:
C12N 15/115
C12N 15/11
C12N 15/113
A61K 9/127
A61K 47/54
A61K 47/69
Abstract:
Defined multi-conjugate oligonucleotides can have predetermined sizes and compositions. For example, in various embodiment, defined multi-conjugate oligonucleotides can have advantageous properties, for example in the form of defined multi-conjugate siRNA (i.e., including two, three or more siRNA) having enhanced intracellular delivery and/or multi-gene silencing effects. In various embodiment, the defined multi-conjugate oligonucleotides can be synthesized via new synthetic intermediates and methods. The defined multi-conjugate oligonucleotides can be used, for example, in reducing gene expression, biological research, treating or preventing medical conditions, or t9o produce new or altered phenotypes in cells or organisms.

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