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Susan B Lindquist, 683726 Hogan Rd, Vernon Center, NY 13477

Susan Lindquist Phones & Addresses

3726 Hogan Rd, Vernon Center, NY 13477    845-4805386   

38 Eliot St, Canton, MA 02021   

Vernon, NY   

3726 Hogan Rd, Vernon Center, NY 13477   

Work

Company: Whitehead institute for bio-medical research Address: 9 Cambridge Ctr, Cambridge, MA 02142 Phones: 617-2585000 Position: Director Industries: Noncommercial Research Organizations

Education

School / High School: Temple University 1974

Languages

English

Awards

Healthgrades Honor Roll

Ranks

Certificate: Internal Medicine, 1984

Mentions for Susan B Lindquist

Career records & work history

Medicine Doctors

Susan Lindquist Photo 1

Dr. Susan M Lindquist, Cambridge MA - MD (Doctor of Medicine)

Specialties:
Internal Medicine
Address:
9 Cambridge Ctr Suite 657, Cambridge, MA 02142
617-2585184 (Phone)
Certifications:
Internal Medicine, 1984
Awards:
Healthgrades Honor Roll
Languages:
English
Education:
Medical School
Temple University
Graduated: 1974
Medical School
Fulkner-Shattuck Hosps
Graduated: 1974
Medical School
Baystate Mc
Graduated: 1974
Medical School
Yale University
Graduated: 1974

Susan Lindquist resumes & CV records

Resumes

Susan Lindquist Photo 48

Project Director At Parexel

Position:
Project Director at PAREXEL
Location:
Paradise Valley, Arizona
Industry:
Pharmaceuticals
Work:
PAREXEL since Nov 2010
Project Director
PAREXEL International Oct 2008 - Nov 2010
Senior Project Manager
PAREXEL International May 2006 - Oct 2008
Project Manager
PAREXEL International Dec 2004 - May 2006
Senior Clinical Research Associate/Clinical Lead
PAREXEL International Dec 2001 - Dec 2004
Clinical Research Associate II
PAREXEL International Dec 2000 - Dec 2001
Clinical Research Associate I
University of California at San Diego May 1998 - Dec 2000
Research Associate II
Education:
San Diego State University-California State University 1998 - 2000
MPH, Epidemiology
Baylor University 1994 - 1998
BA, Biology
Skills:
Clinical Trials, Oncology, Therapeutic Areas, Phase I, Vaccines, Gastroenterology, Rheumatoid Arthritis, Osteoporosis, EDC, Clinical Monitoring, CTMS, CRO
Susan Lindquist Photo 49

Susan Lindquist

Location:
United States
Susan Lindquist Photo 50

Member At Whitehead Institute

Location:
Greater Boston Area
Industry:
Research
Susan Lindquist Photo 51

Susan Lindquist

Location:
United States
Susan Lindquist Photo 52

Susan Lindquist

Location:
United States
Susan Lindquist Photo 53

Writer At Partylite Worldwide, Inc

Position:
Writer at PartyLite Worldwide, Inc
Location:
Greater Boston Area
Industry:
Writing and Editing
Work:
PartyLite Worldwide, Inc
Writer

Publications & IP owners

Wikipedia

Susan Lindquist Photo 62

Susan Lindquist

Susan Lindquist (born June 5, 1949) is a professor of biology at MIT specializing in molecular biology, particularly the protein folding problem within a family of...

Us Patents

Yeast Screens For Treatment Of Human Disease

US Patent:
7045290, May 16, 2006
Filed:
Feb 15, 2002
Appl. No.:
10/077584
Inventors:
Susan Lindquist - Chestnut Hill MA, US
Sylvia Krobitsch - Berlin, DE
Tiago Fleming Outeiro - Cambridge MA, US
Assignee:
The University of Chicago - Chicago IL
International Classification:
C12Q 1/68
US Classification:
435 6
Abstract:
Screening methods for identifying substances that provide therapeutic value for various diseases associated with protein misfolding are provided. Genetic and chemical screening methods are provided using a yeast system. The methods of the invention provide a rapid and cost-effective method to screen for compounds that prevent protein misfolding and/or protein fibril formation and/or protein aggregation which includes numerous neurodegenerative diseases including Parkinson's disease, Alzheimer's disease, Huntington's disease as well as non-neuronal diseases such as type 2 diabetes.

Yeast Screens For Treatment Of Human Disease

US Patent:
8039209, Oct 18, 2011
Filed:
Feb 27, 2006
Appl. No.:
11/363870
Inventors:
Susan Lindquist - Chestnut Hill MA, US
Sylvia Krobitsch - Berlin, DE
Tiago Fleming Outeiro - Cambridge MA, US
Assignee:
The University of Chicago - Chicago IL
International Classification:
C12Q 1/68
US Classification:
435 6, 43525411, 43525421
Abstract:
Screening methods for identifying substances that provide therapeutic value for various diseases associated with protein misfolding are provided. Genetic and chemical screening methods are provided using a yeast system. The methods of the invention provide a rapid and cost-effective method to screen for compounds that prevent protein misfolding and/or protein fibril formation and/or protein aggregation which includes numerous neurodegenerative diseases including Parkinson's disease, Alzheimer's disease, Huntington's disease as well as non-neuronal diseases such as type 2 diabetes.

Compositions And Methods For Treatment Of Protein Misfolding Diseases

US Patent:
8192986, Jun 5, 2012
Filed:
May 4, 2005
Appl. No.:
11/568653
Inventors:
Susan L. Lindquist - Chestnut Hill MA, US
Martin Duennwald - Cambridge MA, US
Assignee:
Whitehead Institute for Biomedical Research - Cambridge MA
International Classification:
C12Q 1/00
C12Q 1/02
G01N 33/53
US Classification:
435375, 435 72, 435 4, 435 29
Abstract:
Disclosed are methods for identifying compounds that modulate huntingtin mediated impairment of protein degradation pathways. Compounds identified by such screens can be used as candidate drugs for the treatment of prevention of polyglutamine diseases such as Huntington's Disease.

Hsp90, Buffering And Drug Resistance

US Patent:
8343913, Jan 1, 2013
Filed:
Jul 5, 2005
Appl. No.:
11/175515
Inventors:
Leah Cowen - Jamaica Plain MA, US
Susan L. Lindquist - Chestnut Hill MA, US
Assignee:
Whitehead Institute for Biomedical Research - Cambridge MA
International Classification:
A01N 37/18
A01N 43/64
A61K 38/00
A61K 31/41
A61K 45/00
A61K 47/44
A61P 31/10
C07D 293/00
C07D 421/00
C07D 517/00
C07D 291/00
C07D 419/00
C07D 515/00
C07D 285/00
C07D 417/00
C07D 513/00
C07D 273/00
C07D 413/00
C07D 498/00
C07D 277/04
C07D 277/08
C07D 275/02
C07D 249/08
C07D 233/00
C07D 233/02
C07D 231/00
US Classification:
514 33, 514359, 4242831, 548100, 548122, 548123, 548124, 548146, 548206, 548240, 5482622, 5483001, 5483561
Abstract:
A method of reducing antifungal drug resistance in which Hsp inhibitors, such as Hsp90 inhibitors, are used.

Modulators Of Alpha-Synuclein Toxicity

US Patent:
8399241, Mar 19, 2013
Filed:
Dec 1, 2005
Appl. No.:
11/720586
Inventors:
Susan L. Lindquist - Chestnut Hill MA, US
Aaron D. Gitler - Philadelphia PA, US
Anil Cashikar - Martinez GA, US
Antony A. Cooper - Sydney, AU
Cole M. Haynes - New York NY, US
Assignee:
Whitehead Institute for Biomedical Research - Cambridge MA
The Curators of the University of Missouri - Columbia MO
International Classification:
C12N 1/16
US Classification:
4352542, 43525421, 435325, 435375
Abstract:
Disclosed are compositions and methods for modulating expression of genes that function at the step of ER of Golgi trafficking. Compounds that modulate expression of these genes of activity of the encoded proteins can be used to inhibit alpha-synuclein mediated toxicity and used to threat of prevent synucleinopathies such as Parkinson's disease. Also disclosed are methods of identifying inhibitors of alpha-synuclein mediated toxicity.

Compounds, Compositions And Methods Of Inhibiting Alpha-Synuclein Toxicity

US Patent:
8440705, May 14, 2013
Filed:
Sep 16, 2005
Appl. No.:
11/575481
Inventors:
Susan L. Lindquist - Chestnut Hill MA, US
Tiago Outeiro - Cambridge MA, US
Assignee:
Whitehead Institute for Biomedical Research - Cambridge MA
FoldRx Pharmaceuticals, Inc. - Cambridge MA
International Classification:
C07D 277/82
A61K 31/428
US Classification:
514367, 548161
Abstract:
Compounds and compositions are provided for treatment or amelioration of one or more symptoms of α-synuclein toxicity, α-synuclein mediated diseases or diseases in which α-synuclein fibrils are a symptom or cause of the disease. In one embodiment, the compounds for use in the compositions and methods are heteroaryl acylguanidines, heteroarylhydrazones, dihydropyridones, heteroaryl and aryl styryl ketones, and heteroarylpyrazoles.

Modulators Of Alpha-Synuclein Toxicity

US Patent:
8501465, Aug 6, 2013
Filed:
Dec 22, 2008
Appl. No.:
12/809859
Inventors:
Susan L. Lindquist - Chestnut Hill MA, US
Aaron D. Gitler - Philadelphia PA, US
Assignee:
Whitehead Institute for Biomedical Research - Cambridge MA
International Classification:
C12N 15/63
C12N 15/85
C07H 21/04
US Classification:
4353201, 536 231, 435325
Abstract:
Disclosed are genes that, when overexpressed in cells expressing alpha-synuclein, either suppress or enhance alpha-synuclein mediated cellular toxicity. Compounds that modulate expression of these genes or activity of the encoded proteins can be used to inhibit alpha-synuclein mediated toxicity and used to treat or prevent synucleinopathies such as Parkinson's disease. Also disclosed are methods of identifying inhibitors of alpha-synuclein mediated toxicity.

Mammalian Prion Proteins And Transgenic Mice Expressing Them

US Patent:
2004004, Mar 11, 2004
Filed:
May 15, 2003
Appl. No.:
10/438628
Inventors:
Susan Lindquist - Chestnut Hill MA, US
Jiyan Ma - Chicago IL, US
International Classification:
C12Q001/00
G01N033/53
G01N033/567
US Classification:
435/004000, 435/007200
Abstract:
The invention relates to methods of identifying, detecting or designing drugs that inhibit the formation of or accumulation of PrP, PrPor both in cells; to drugs that inhibit the formation of or accumulation of PrP, PrPor both in cells; to methods of preventing or reducing the adverse effects of PrP, PrPor both in humans; and to transgenic nonhuman mammals, such as transgenic mice, that ectopically express PrP.

Amazon

Susan Lindquist Photo 63

Heat Shock

Publisher:
Springer
Binding:
Paperback
Pages:
320
ISBN #:
3642766811
EAN Code:
9783642766817
During the last years the heat shock response has been stu- died as a model system to analyze control mechanisms regula- ting the synthesis of heat shock proteins providing impor- tant general insight into the regulation of gene expression. But the major revelation, which has sparked interest ...
Susan Lindquist Photo 64

Summer Soldiers

Author:
Susan Hart Lindquist
Publisher:
Yearling
Binding:
Paperback
Pages:
192
ISBN #:
0440415373
EAN Code:
9780440415374
Reminiscent of Stand by Me and Lily's Crossing, this story of courage and camaraderie during World War I will touch the hearts of readers.Joe is trying hard to be brave. His father has left to fight in the Great War, and now it's up to him, at age 11, to keep his household and sheep ranch running sm...
Susan Lindquist Photo 65

Wander

Author:
Susan Hart Lindquist
Publisher:
Yearling
Binding:
Paperback
Pages:
133
ISBN #:
0440414431
EAN Code:
9780440414438
He just appears one day--a grayish dog with white-tipped ears and a tail that wags like crazy. And he keeps coming back, until it feels to James and his younger sister, Sary, as if the old stray is their very own. Soon they've given the dog a name, and after that both children are bound to protect h...
Susan Lindquist Photo 66

Walking The Rim

Author:
Susan Hart Lindquist
Publisher:
Boyds Mills Pr
Binding:
Library Binding
Pages:
139
ISBN #:
1563970988
EAN Code:
9781563970986
When an earthquake separates Rudy from his parents during their annual family camping trip, the boy discovers a way of living unlike the way to which he has grown accustomed and takes his first steps toward adulthood.
Susan Lindquist Photo 67

Hund Sucht Familienanschluss. ( Ab 10 J.).

Author:
Susan Hart Lindquist
Publisher:
Ueberreuter
Binding:
Hardcover
ISBN #:
380002764X
EAN Code:
9783800027644
Susan Lindquist Photo 68

Wander

Author:
Susan Hart Lindquist
Publisher:
Dell Publishing Co.. Inc.
Binding:
Paperback

Isbn (Books And Publications)

Wander

Author:
Susan Hart Lindquist
ISBN #:
0385325630

Summer Soldiers

Author:
Susan Hart Lindquist
ISBN #:
0385326416

Wander

Author:
Susan Hart Lindquist
ISBN #:
0440414431

Stress-Induced Proteins: Proceedings Of A Hoffmann-La Roche-Director'S Sponsors-Ucla Symposium, Held At Keystone, Colorado, April 10-16, 1988

Author:
Susan Lindquist
ISBN #:
0845126954

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