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Susan Leslie Holderman, 6813202 W Los Bancos Dr, Sun City, AZ 85375

Susan Holderman Phones & Addresses

13202 W Los Bancos Dr, Sun City West, AZ 85375    253-9259005   

Federal Way, WA   

Cosmopolis, WA   

Tacoma, WA   

Aberdeen, WA   

Kiona, WA   

30157 16Th Ave SW, Federal Way, WA 98023    253-6779006   

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Susan Leslie Holderman

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Position: Machine Operators, Assemblers, and Inspectors Occupations

Education

Degree: Associate degree or higher

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Susan Holderman

Publications & IP owners

Us Patents

Fgf Homologs

US Patent:
6352971, Mar 5, 2002
Filed:
Aug 5, 1999
Appl. No.:
09/368951
Inventors:
Theresa A. Deisher - Seattle WA
Darrell C. Conklin - Seattle WA
Fenella Raymond - Seattle WA
Thomas R. Bukowski - Seattle WA
Susan D. Holderman - Kirkland WA
Birgit Hansen - Seattle WA
Paul O. Sheppard - Redmond WA
Assignee:
ZymoGenetics, Inc. - Seattle WA
International Classification:
A61K 3800
US Classification:
514 2, 435 71, 530350, 5303871, 4241921
Abstract:
The present invention relates to polynucleotide and polypeptide molecules for zFGF-5 a novel member of the FGF family. The polypeptides, and polynucleotides encoding them, are proliferative for muscle cells and may be used for remodelling cardiac tissue and improving cardiac function. The present invention also includes antibodies to the zFGF-5 polypeptides.

Fgf Homologs

US Patent:
6518236, Feb 11, 2003
Filed:
Jan 13, 1999
Appl. No.:
09/229947
Inventors:
Theresa A. Deisher - Seattle WA
Darrell C. Conklin - Seattle WA
Fenella Raymond - Seattle WA
Thomas R. Bukowski - Seattle WA
Susan D. Holderman - Seattle WA
Birgit Hansen - Seattle WA
Paul O. Sheppard - Redmond WA
Assignee:
ZymoGenetics, Inc. - Seattle WA
International Classification:
C07K 1450
US Classification:
514 2, 514 12, 530350, 530399, 435 697
Abstract:
The present invention relates to polynucleotide and polypeptide molecules for zFGF5 a novel member of the FGF family. The polypeptides, and polynucleotides encoding them, are proliferative for muscle cells, in particular cardiac cells and may be used for remodeling cardiac tissue and improving cardiac function. The present invention also includes antibodies to the zFGF5 polypeptides.

Fgf Homolog Polypeptides

US Patent:
7247608, Jul 24, 2007
Filed:
Oct 19, 2001
Appl. No.:
10/037922
Inventors:
Theresa A. Deisher - Seattle WA, US
Darrell C. Conklin - Seattle WA, US
Fenella Raymond - Seattle WA, US
Thomas R. Bukowski - Seattle WA, US
Susan D. Holderman - Kirkland WA, US
Birgit Hansen - Seattle WA, US
Paul O. Sheppard - Redmond WA, US
Assignee:
ZymoGenetics, Inc. - Seattle WA
International Classification:
A61K 38/18
A61K 39/00
C07K 14/50
US Classification:
514 2, 530350, 5303871, 530300, 4241921
Abstract:
The present invention relates to polynucleotide and polypeptide molecules for zFGF-5 a novel member of the FGF family. The polypeptides, and polynucleotides encoding them, are proliferative for muscle cells and may be used for remodelling cardiac tissue and improving cardiac function. The present invention also includes antibodies to the zFGF-5 polypeptides.

Il-21 Production In Prokaryotic Hosts

US Patent:
7250274, Jul 31, 2007
Filed:
Dec 12, 2003
Appl. No.:
10/735149
Inventors:
Chung Chan - Issaquah WA, US
Bruce L. Zamost - Seattle WA, US
Douglas C. Covert - Mukilteo WA, US
Hong Y. Liu - Seattle WA, US
Karen S. De Jongh - Seattle WA, US
Jeffrey D. Meyer - Lake Forest Park WA, US
Susan D. Holderman - Seattle WA, US
Assignee:
ZymoGenetics, Inc. - Seattle WA
International Classification:
C12P 21/02
US Classification:
435 695, 4353201, 4352523, 4352528, 530351
Abstract:
The expression vectors and methods using an expression system for the large scale production of IL-21 are described. The vectors utilize the IL-21 coding sequence with specific changes in nucleotides in order to optimize codons and mRNA secondary structure for translation in Using the expression vectors, the IL-21 gene was produced in to a level of greater than 1 g/L in fed batch fermentation. Also included are OmpT deficient strains transformed with an IL-21 expression vector.

Fgf Homologs And Antibodies Thereto

US Patent:
7563438, Jul 21, 2009
Filed:
May 22, 2007
Appl. No.:
11/752197
Inventors:
Theresa A. Deisher - Seattle WA, US
Darrell C. Conklin - Seattle WA, US
Fenella C. Raymond - Seattle WA, US
Thomas R. Bukowski - Seattle WA, US
Susan D. Holderman - Seattle WA, US
Paul O. Sheppard - Redmond WA, US
Assignee:
ZymoGenetics, Inc. - Seattle WA
International Classification:
A61K 39/395
C07K 16/00
C07K 16/22
US Classification:
4241301, 4241391, 4241411, 4241581, 5303871, 5303879, 5303881, 53038824, 530402
Abstract:
The present invention relates to antibodies and fragments thereof, polynucleotide and polypeptide molecules for zFGF5 a novel member of the FGF family. The polypeptides, and polynucleotides encoding them, are proliferative for muscle cells, in particular cardiac cells and may be used for remodeling cardiac tissue and improving cardiac function. The present invention also includes antibodies to the zFGF5 polypeptides.

Isolated Nucleic Acid Sequence Comprising Seq Id No: 14 And Methods Of Using Said Nucleic Acid Sequence

US Patent:
7629445, Dec 8, 2009
Filed:
Oct 12, 2006
Appl. No.:
11/548826
Inventors:
Susan D. Holderman - Seattle WA, US
Chung Chan - Issaquah WA, US
Assignee:
ZymoGenetics, Inc. - Seattle WA
International Classification:
C07H 21/04
C12P 21/06
C12N 5/00
C12N 15/00
US Classification:
536 231, 435 691, 435325, 4353201
Abstract:
The present invention provides methods of using Zven1 and Zven2 polypeptides to increase chemokine production. The present invention also provides methods for treating intestinal motility disorders and improving gastrointestinal function with Zven1 and Zven2 polypeptides.

Testis Specific Protein

US Patent:
2002015, Oct 17, 2002
Filed:
Oct 25, 2001
Appl. No.:
10/001632
Inventors:
Darrell Conklin - Seattle WA, US
Andrew Feldhaus - Lynnwood WA, US
Susan Holderman - Seattle WA, US
Assignee:
ZymoGenetics, Inc.
International Classification:
A61K038/17
C07H021/04
C12P021/02
C12N005/06
C07K014/435
US Classification:
514/012000, 530/324000, 435/069100, 435/325000, 435/320100, 536/023500
Abstract:
Tissue-specific markers can be used to enhance diagnosis, staging, and treatment of cancer, as well as to detect metastases of tumors derived from that tissue. The present invention provides a novel human gene, designated as “Zalpha16,” which is preferentially expressed in testicular tissue. TESTIS SPECIFIC PROTEIN

Novel Fgf Homologs

US Patent:
2003000, Jan 9, 2003
Filed:
Feb 21, 2002
Appl. No.:
10/081347
Inventors:
Theresa Deisher - Seattle WA, US
Darrell Conklin - Seattle WA, US
Fenella Raymond - Seattle WA, US
Thomas Bukowski - Seattle WA, US
Susan Holderman - Seattle WA, US
Paul Sheppard - Redmond WA, US
Assignee:
ZymoGenetics, Inc.
International Classification:
C07K017/00
C07K014/00
C07K001/00
C12N005/02
C12N005/00
C12N015/74
C12N015/70
C12N015/63
C12N015/00
C12N015/09
C12P021/06
C07H021/04
A61K038/00
US Classification:
435/069100, 435/325000, 435/320100, 514/012000, 530/350000, 536/023500
Abstract:
The present invention relates to polynucleotide and polypeptide molecules for ZFGF5 a novel member of the FGF family. The polypeptides, and polynucleotides encoding them, are proliferative for muscle cells, in particular cardiac cells and may be used for remodeling cardiac tissue and improving cardiac function. The present invention also includes antibodies to the zFGF5 polypeptides.

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