Tie ZhangSunnyvale, CA
Tie Zhang Phones & Addresses
Sunnyvale, CA
Oakland, CA
San Francisco, CA
819 Sacramento St, San Francisco, CA 94108 415-9862670
Mentions for Tie Zhang
Publications & IP owners
Us Patents
Human Anti-Ngf Neutralizing Antibodies As Selective Ngf Pathway Inhibitors
US Patent:
2016030, Oct 20, 2016
Filed:
Apr 22, 2016
Appl. No.:
15/136832
Inventors:
- Thousand Oaks CA, US
- Princeton NJ, US
Haichun HUANG - Fremont CA, US
Heather INOUE - Oak Park CA, US
Tie J. ZHANG - Thousand Oaks CA, US
Frank MARTIN - Newbury Park CA, US
- Princeton NJ, US
Haichun HUANG - Fremont CA, US
Heather INOUE - Oak Park CA, US
Tie J. ZHANG - Thousand Oaks CA, US
Frank MARTIN - Newbury Park CA, US
Assignee:
AMGEN INC. - Thousand Oaks CA
E.R. SQUIBB & SONS, L.L.C. - Princeton NJ
E.R. SQUIBB & SONS, L.L.C. - Princeton NJ
International Classification:
C07K 16/22
G01N 33/74
G01N 33/74
Abstract:
This invention provides antibodies that interact with or bind to human nerve growth factor (NGF) and neutralize the function of NGF thereby. The invention also provides pharmaceutical compositions of said antibodies and methods for neutralizing NGF function, and particularly for treating NGF-related disorders (e.g., chronic pain) by administering a pharmaceutically effective amount of anti-NGF antibodies. Methods of detecting the amount of NGF in a sample using anti-NGF antibodies are also provided.
Human Anti-Ngf Neutralizing Antibodies As Selective Ngf Pathway Inhibitors
US Patent:
2016023, Aug 18, 2016
Filed:
Jan 19, 2016
Appl. No.:
15/000771
Inventors:
- Thousand Oaks CA, US
- Princeton NJ, US
Haichun Huang - Fremont CA, US
Heather Inoue - Oak Park CA, US
Tie J. Zhang - Thousand Oaks CA, US
Frank Martin - Newbury Park CA, US
- Princeton NJ, US
Haichun Huang - Fremont CA, US
Heather Inoue - Oak Park CA, US
Tie J. Zhang - Thousand Oaks CA, US
Frank Martin - Newbury Park CA, US
International Classification:
C07K 16/22
Abstract:
This invention provides antibodies that interact with or bind to human nerve growth factor (NGF) and neutralize the function of NGF thereby. The invention also provides pharmaceutical compositions of said antibodies and methods for neutralizing NGF function, and particularly for treating NGF-related disorders (e.g., chronic pain) by administering a pharmaceutically effective amount of anti-NGF antibodies. Methods of detecting the amount of NGF in a sample using anti-NGF antibodies are also provided.
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