Tracey Ann Knapp, 49San Leandro, CA

5494592, Feb 27, 1996

Jan 13, 1995

8/372890

Allen Latham - Jamaica Plain MA
Glen E. Jorgensen - Marlborough MA
Theodoor H. S. Sibinga - Boston MA
Joseph R. Plante - Millis MA
Tracey E. Knapp - Hanover MA

Haemonetics Corporation - Braintree MA

A61M 3700
B01D 2126

210805

An apheresis apparatus and method is disclosed for increasing the purity and yield of platelets separated from donated whole blood in a centrifuge. The whole blood in the centrifuge is diluted by recirculating fluid, such as plasma or saline, at a first flow rate, to mix with further withdrawn whole blood prior to entering the centrifuge. As plasma is collected, it is recirculated through the centrifuge at a second flow rate to further improve the separation between the intermediate density components, i. e. , platelets and white blood cells in the "buffy coat. " The plasma is then recirculated through the centrifuge at a third flow rate and platelets are displaced out of the centrifuge while the plasma is recirculating through the centrifuge at the third flow rate.

D377685, Jan 28, 1997

Sep 26, 1995

D/044778

Theodoor H. S. Sibinga - Norwood MA
Joseph R. Plante - Medway MA
Andrew Lanciano - Plymouth MA
James R. Loible - Foxboro MA
Robert B. Carr - Wellesley MA
David W. Newby - Raynham MA
Tracey E. Knapp - Coralville IA

Haemonetics Corp. - Braintree MA

D24108

5387088, Feb 7, 1995

Jan 18, 1994

8/183483

Tracey E. Knapp - Hanover MA
James R. Loible - Foxborough MA
Andrew P. Lanciano - Plymouth MA
Victor Sacco - Burlington MA
Nicholas D. Baruch - North Smithfield RI

Haemonetics Corporation - Braintree MA

F04B 4308

417 53

A peristaltic pump assembly for easy loading includes a pump housing having a curved surface. A stationary tubing manifold from which a loop of tubing extends is positioned in line with the curved surface. A pump rotor rotatable about an axis is positioned adjacent to the curved surface. The rotor has a groove located above the curved surface encircling the rotor for retaining and stretching the loop of tubing in loading position between the rotor and the manifold. During loading, a notch located on the rotor progressively captures and urges the tubing downward between the curved surface and the pump rotor when the rotor is rotated.

5607579, Mar 4, 1997

Sep 28, 1995

8/536499

Allen Latham - Jamaica Plain MA
Glen E. Jorgensen - Marlborough MA
Theodoor H. S. Sibinga - Boston MA
Joseph R. Plante - Millis MA
Tracey E. Knapp - Hanover MA

Haemonetics Corporation - Braintree MA

B01D 2126
B01D 2132
A61M 138
B04B 1102

2101951

An apheresis apparatus for increasing the purity and yield of platelets separated from donated whole blood by centrifugation incorporates a centrifuge for separating whole blood into lower, intermediate, and higher density components. The centrifuge has inlet and outlet ports in selective fluid communication with a container for receiving lower density blood component from the outlet port. A pump is coupled to the container and the inlet port for recirculating lower density blood component from the first container through the inlet port into the centrifuge at a first, substantially constant, rate so as to widen the region of the centrifuge occupied by the intermediate density component without causing the intermediate density component to exit the centrifuge, and subsequently at a second rate, so as to displace intermediate density component from the centrifuge.