Inventors:
WIlliam C. Burhans - Buffalo NY, US
Catherine E. Prudom - Harrisonburg VA, US
Christopher P. Allen - Fort Collins CO, US
Oleg Ursu - Albuquerque NM, US
Anna Waller - Albuquerque NM, US
Larry A. Sklar - Albuquerque NM, US
Assignee:
STC.UNM - Albuquerque NM
HEALTH RESEARCH, INC. - Buffalo NY
International Classification:
A61K 31/58
C12Q 1/02
A61K 31/56
US Classification:
514176, 514182, 540109, 552502, 506 10, 435 34
Abstract:
Provided are methods and compositions for reducing superoxide anions such that a prophylactic or therapeutic effect against conditions associated with excess oxidative stress achieved. The compositions and methods provide for reducing inflammation and for enhancing lifespan of eukaryotic organisms. A screen for identifying compounds that can be used in these methods is also provided.