Xavier D Gomes, 4230 Otis St, Hartford, CT 06114
Xavier Gomes Phones & Addresses
30 Otis St, Hartford, CT 06114
211 Jordan Ln, Wethersfield, CT 06109 860-5299383
Mentions for Xavier D Gomes
Publications & IP owners
Us Patents
System And Method For Operation Of Isfet Arrays Using Ph Inert Reference Sensors
US Patent:
2014007, Mar 13, 2014
Filed:
Aug 19, 2013
Appl. No.:
13/970167
Inventors:
Gianni Calogero Ferreri - Northford CT, US
Sagnik Basuray - Columbia MO, US
Arthika Bappal - Bridgeport CT, US
Suresh Gopalkrishna Shenoy - Branford CT, US
Xavier Victor Gomes - Wallingford CT, US
Sagnik Basuray - Columbia MO, US
Arthika Bappal - Bridgeport CT, US
Suresh Gopalkrishna Shenoy - Branford CT, US
Xavier Victor Gomes - Wallingford CT, US
International Classification:
C12Q 1/68
H01L 27/105
H01L 27/105
US Classification:
506 2, 506 16, 257253
Abstract:
An embodiment of a method for sequencing a species of nucleic acid template using pH inert reference sensors is described that comprises the steps of: introducing a nucleotide species to an array of wells where a plurality of the wells comprise a species of nucleic acid template and a plurality of the wells comprise a plurality of functional groups with a high pH buffering characteristic, and in at least a first well a polymerase species incorporates the nucleotide species into a plurality of strands complementary to the species of nucleic acid template disposed in the first well and results in a release of a plurality of hydrogen ions; detecting a signal in the first well that is responsive to the hydrogen ions and one or more noise sources; detecting a signal in a second well comprising the functional groups with the high pH buffering characteristic that is responsive to the one or more noise sources; and subtracting the second well signal from the first well signal to generate a corrected signal associated with the detected hydrogen ions.
NOTICE: You may not use BackgroundCheck or the information it provides to make decisions about employment, credit, housing or any other purpose that would require Fair Credit Reporting Act (FCRA) compliance. BackgroundCheck is not a Consumer Reporting Agency (CRA) as defined by the FCRA and does not provide consumer reports.