Xiaodong Xu resumes & CV records
Resumes
Xiaodong Xu
Xiaodong Dong Xu, 5480 Audubon Rd, Wellesley, MA 02481
Xiaodong Xu Phones & Addresses
Wellesley, MA
4564 Summerhill Dr, Doylestown, PA 18901 215-2300528
10 Tunison Ln, Bridgewater, NJ 08807 908-9279176
57 Huntley Way, Bridgewater, NJ 08807
New York, NY
Rush, KY
Elmhurst, NY
Work
Company:
Pharmabridge, inc
Address:
3805 Old Easton Rd, Gardenville, PA 18902
Phones:
215-5896350
Position:
Chief executive officer
Industries:
Commercial Physical and Biological Research
Mentions for Xiaodong Dong Xu
Publications & IP owners
Us Patents
6-O-Carbamoyl Ketolide Antibacterials
US Patent:
6472372, Oct 29, 2002
Filed:
Feb 1, 2001
Appl. No.:
09/773788
Inventors:
Todd C. Henninger - Neshanic Station NJ
Xiaodong Xu - Bridgewater NJ
Xiaodong Xu - Bridgewater NJ
Assignee:
Ortho-McNeil Pharmaceuticals, Inc. - Raritan NJ
International Classification:
A61K 3170
US Classification:
514 29, 536 79, 536 185
Abstract:
6-O-Carbamoyl ketolide antibacterials of the formula: wherein R , R , R , R , R , R , X, Xâ, Y, and Yâ are as described herein and in which the substituents have the meaning indicated in the description. These compounds are useful as antibacterial agents.
6-O-Carbamoyl Ketolide Antibacterials
US Patent:
6613747, Sep 2, 2003
Filed:
Dec 5, 2001
Appl. No.:
10/011937
Inventors:
Todd C. Henninger - Neshanic Station NJ
Xiaodong Xu - Bridgewater NJ
Xiaodong Xu - Bridgewater NJ
Assignee:
Ortho-McNeil Pharmaceutical, Inc. - Raitan NJ
International Classification:
A61K 3170
US Classification:
514 29, 536 71, 536 185
Abstract:
6-O-Carbamoyl ketolide antibacterials of the formula: wherein R , R , R , R , R , R , X, Xâ, Y, and Yâ are as described herein and in which the substituents have the meaning indicated in the description. These compounds are useful as antibacterial agents.
6-O-Acyl Ketolide Antibacterials
US Patent:
6825170, Nov 30, 2004
Filed:
Nov 21, 2002
Appl. No.:
10/301412
Inventors:
Todd C. Henninger - High Bridge NJ
Mark J. Macielag - Branchburg NJ
Manomi A. Tennakoon - Bridgewater NJ
Xiaodong Xu - Bridgewater NJ
Mark J. Macielag - Branchburg NJ
Manomi A. Tennakoon - Bridgewater NJ
Xiaodong Xu - Bridgewater NJ
Assignee:
Ortho-McNeil Pharmaceutical, Inc. - Raritan NJ
International Classification:
A61K 3170
US Classification:
514 29, 536 74, 536 185
Abstract:
6-O-Acyl ketolide antibacterials of the formula: wherein R , R , R , R , W, X, Xâ, Y, and Yâ are as described herein and in which the substituents have the meaning indicated in the description. These compounds are useful as antibacterial agents.
7-Amino Alkylidenyl-Heterocyclic Quinolones And Naphthyridones
US Patent:
7732612, Jun 8, 2010
Filed:
Mar 21, 2005
Appl. No.:
11/084987
Inventors:
Eugene B. Grant - Flemington NJ, US
Mark J. Macielag - Branchburg NJ, US
Steven David Paget - Hillsborough NJ, US
Xiaoqing Xu - Plainsboro NJ, US
Xiaodong Xu - Doylestown PA, US
Mark J. Macielag - Branchburg NJ, US
Steven David Paget - Hillsborough NJ, US
Xiaoqing Xu - Plainsboro NJ, US
Xiaodong Xu - Doylestown PA, US
Assignee:
Janssen Pharmaceutica, N.V. - Beerse
International Classification:
C07D 215/38
US Classification:
546159, 546156
Abstract:
The present invention relates to compounds having a structure according to Formula I.
Substituted Triazolo[1,5-A]Pyrimidines As Antiviral Agents
US Patent:
8609668, Dec 17, 2013
Filed:
May 4, 2007
Appl. No.:
12/299532
Inventors:
Andrea Cuconati - Oreland PA, US
Timothy M. Block - Doylestown PA, US
Xiaodong Xu - Doylestown PA, US
Timothy M. Block - Doylestown PA, US
Xiaodong Xu - Doylestown PA, US
Assignee:
Philadelphia Health & Education Corporation - Philadelphia PA
Institute For Hepatitis and Virus Research - Doylestown PA
Institute For Hepatitis and Virus Research - Doylestown PA
International Classification:
A61K 31/519
A61P 31/20
C07D 487/04
A61P 31/20
C07D 487/04
US Classification:
5142593, 544254
Abstract:
A pharmaceutical composition comprising an effective amount of a compound of formulas (I-III) and a pharmaceutically acceptable carrier. Methods for treating a hepatitis virus in a patient comprising administering an effective amount of the compound of formulas (I-III) are also presented.
7-Amino Alkylidenyl-Heterocyclic Quinolones And Naphthyridones
US Patent:
2009015, Jun 18, 2009
Filed:
Nov 11, 2008
Appl. No.:
12/268529
Inventors:
Benjamin Davis - Birmingham AL, US
Shu-Chen Lin - Doylestown PA, US
Mark J. Macielag - Branchburg NJ, US
Xiaoqing Xu - Plainsboro NJ, US
Xiaodong Xu - Doylestown PA, US
Bin Zhu - Hillsborough NJ, US
Shu-Chen Lin - Doylestown PA, US
Mark J. Macielag - Branchburg NJ, US
Xiaoqing Xu - Plainsboro NJ, US
Xiaodong Xu - Doylestown PA, US
Bin Zhu - Hillsborough NJ, US
International Classification:
A61K 31/5365
C07D 471/04
A61K 31/4375
C07D 401/04
A61K 31/4709
C07D 498/16
C07D 471/04
A61K 31/4375
C07D 401/04
A61K 31/4709
C07D 498/16
US Classification:
51421021, 546123, 514300, 546178, 514312, 544101, 5142302
Abstract:
The present invention relates to compounds having a structure according to Formula (I)wherein n, m, z, R, R, R, R, R, R, A, E, X, Y, a and b are as defined above; or an optical isomer, diastereomer or enantiomer thereof; a pharmaceutically acceptable salt, hydrate, or prodrug thereof.
Novel Imino Sugar Derivatives Demonstrate Potent Antiviral Activity And Reducted Toxicity
US Patent:
2011018, Aug 4, 2011
Filed:
Sep 2, 2009
Appl. No.:
13/061734
Inventors:
Timothy M. Block - Doylestown PA, US
Jinhong Chang - Chalfont PA, US
Xiaodong Xu - Doylestown PA, US
Jinhong Chang - Chalfont PA, US
Xiaodong Xu - Doylestown PA, US
Assignee:
INSTITUTE FOR HEPATITIS AND VIRUS RESEARCH - Doylestown PA
International Classification:
C12N 5/02
C07D 211/40
C07D 211/40
US Classification:
435375, 546219
Abstract:
Imino sugars, such as deoxynojirimycin (DNJ), are glucose analogues that selectively inhibit cellular α-glucosidase I and II (enzymes that process N-linked glycans in glycoprotein) and exhibit broad spectrum antiviral activities against many enveloped viruses. Previously we have reported a novel DNJ derivative, OSL-95II, with antiviral activity and reduced cytotoxicity. In order to develop imino sugars with more potent antiviral activity as well as improved toxicity profile, OSL-95II was modified by diversifying the nitrogen linked alkylated side chain. The antiviral activities were initially tested in bovine viral diarrhea virus (BVDV) infected MDBK cells, yielding several imino sugar derivatives with novel structure and superior antiviral activity and toxicity profile. Furthermore, these new compounds were shown to be active against Dengue virus (DV) and West Nile virus (WNV) infection in BHK cells where potent anti-DV activity having submicromolar EC50 values and SI of greater than 900. These compounds represent a new generation of iminio sugars and their analogues, having application in the clinical treatment of infection of DV and other members of flaviviridae.
Novel Inhibitors Of Secretion Of Hepatitis B Virus Antigens
US Patent:
2013030, Nov 14, 2013
Filed:
Oct 4, 2011
Appl. No.:
13/877870
Inventors:
Xiaodong Xu - Doylestown PA, US
Andrea Cuconati - Oreland PA, US
Timothy M. Block - Doylestown PA, US
Tong Xiao - Edison NJ, US
Andrea Cuconati - Oreland PA, US
Timothy M. Block - Doylestown PA, US
Tong Xiao - Edison NJ, US
Assignee:
INSTITUTE FOR HEPALITIS AND VIRUS RESEARCH - Doylestown PA
International Classification:
A61K 31/519
C07D 487/04
A61K 45/06
C07D 487/04
A61K 45/06
US Classification:
5142621
Abstract:
Pharmaceutical compositions of the invention comprise triazolopyrimidines useful for the treatment of hepatitis virus in a patient.
Possible Relatives
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