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Xiaoyu Zhang, 35Santa Clara, CA

Xiaoyu Zhang Phones & Addresses

Santa Clara, CA   

Campbell, CA   

Fremont, CA   

Sunnyvale, CA   

Hyattsville, MD   

Greenbelt, MD   

College Park, MD   

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Xiaoyu Zhang Photo 26

Xiaoyu Zhang

Location:
United States

Publications & IP owners

Us Patents

Methods For Treating Cancers And Diseases Associated With 4-1Bb (Cd137) Expression

US Patent:
2012007, Mar 29, 2012
Filed:
May 11, 2010
Appl. No.:
13/320267
Inventors:
Scott Strome - Reistertown MD, US
Xiaoyu Zhang - Catonsville MD, US
Assignee:
UNIVERSITY OF MARYLAND, BALTIMORE - Baltimore MD
International Classification:
A61K 39/395
A61K 51/00
C12Q 1/68
G01N 21/75
G01N 33/566
A61P 37/04
A61K 38/17
US Classification:
424 111, 4241731, 4242781, 435 71, 436501, 435 612
Abstract:
The present invention relates to the role of 4-1BB (CD137) ligand and anti-4-1BB (CD137) antibody in the treatment of cancers and diseases associated with 4-1BB (CD137) expression. More particularly, the present invention relates to the use of (i) 4-1BB (CD137) ligand for inducing proliferation and activation and promoting survival of B lymphocytes and (2) anti-4-1BB (anti-CD137) antibody for inhibiting proliferation and activation and inducing death of B lymphocytes.

Change Impact Simulation Analysis

US Patent:
2022036, Nov 17, 2022
Filed:
Jul 21, 2022
Appl. No.:
17/814158
Inventors:
- Mountain View CA, US
Hui Liu - San Ramon CA, US
Vishal Gupta - Milpitas CA, US
Vikas Aggarwal - Brisbane CA, US
Kan Cai - Mountain View CA, US
Xiaoyu Zhang - San Jose CA, US
Assignee:
Google LLC - Mountain View CA
International Classification:
H04L 41/14
H04L 41/28
Abstract:
A system for simulating network configurations includes data processing hardware and memory hardware in communication with the data processing hardware. The memory hardware stores instructions that when executed on the data processing hardware cause the data processing hardware to perform operations. The operations includes receiving one or more parameter changes for a production network model of a network. The operations also include generating a simulation network model including the one or more parameter changes. Another operation includes analyzing the simulated network flow within the simulation network model. The operations also include generating a report including an impact of the parameter changes on the network. The operations may also include receiving a production network log including a recorded workflow for the production network model and simulating the production workflow of the production network log within the simulation network model to generate a simulated network log.

Therapy For The Treatment Of Cancer

US Patent:
2023005, Feb 23, 2023
Filed:
Dec 18, 2020
Appl. No.:
17/787793
Inventors:
- Rockville MD, US
Jon Marc Wigginton - Rockville MD, US
Ezio Bonvini - Rockville MD, US
Paul A. Moore - Rockville MD, US
Scott Koenig - Rockville MD, US
Xiaoyu Zhang - Rockville MD, US
Assignee:
MacroGenics, Inc. - Rockville MD
International Classification:
C07K 16/28
A61P 35/00
C07K 16/32
A61K 45/06
Abstract:
The present invention is directed to regimens for administering one or more Antibody-Based Molecules that bind PD-1 or PD-L1, and LAG-3 (e.g, a PD-1×LAG-3 bispecific molecule) alone, or in combination with an Antibody-Based Molecule that binds a Tumor Antigen (TA) for the treatment of cancer. The invention particularly concerns the use of such regimens in conjunction with PD-1×LAG-3 bispecific molecules. The invention is directed to the use of such molecules, and to the use of pharmaceutical compositions and pharmaceutical kits that contain such molecules and that facilitate the use of such dosing regimens in the treatment of cancer.

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