Xin Xu, 465 Hillcrest Rd, Bedford, MA 01730

2009006, Mar 12, 2009

Apr 22, 2008

12/107456

Yulia Vugmeyster - North Reading MA, US
Xin Xu - Andover MA, US
Xianbin Tian - Andover MA, US
Donald G. Raible - Devon PA, US
Yuji Simon Zhou - Malvern MA, US
Billie Durn - Spring City PA, US

Wyeth - Cambridge MA

A61K 39/395
G06F 19/00
A61P 11/00
A61P 29/00
A61P 35/00

4241581, 702 19

Methods and compositions for reducing or inhibiting, or preventing or delaying the onset of, one or more symptoms associated with an early and/or a late phase of an IL-13-associated disorder or condition using IL-13 binding agents are disclosed. Methods for evaluating the kinetics and/or efficacy of an IL-13 binding agent in treating or preventing an IL-13-associated disorder or condition in a subject, e.g., a human subject, are also disclosed.

2012001, Jan 19, 2012

Jul 14, 2011

13/182560

Martin Hegen - Brookline MA, US
Stephane Hubert Olland - Arlington MA, US
Yulia Vugmeyster - North Reading MA, US
Xin Xu - Andover MA, US

Wyeth LLC - Madison NJ

A61K 47/48
G01N 33/53
A61B 19/00
A61P 29/00
A61P 37/06
G01N 33/566
C07K 17/08
A61K 49/00

4241791, 5303911, 435 721, 800 3, 436501, 206438

The invention relates to modified single domain antigen binding molecules, e.g., SDAB molecules, in particular TNFα-binding SDAB molecules. Method of preparing, and using the modified single domain antigen binding molecules described herein, to treat, e.g., TNFα-associated disorders, are also disclosed.

2022039, Dec 8, 2022

Aug 9, 2022

17/884445

- San Jose CA, US
Xin Xu - Reading MA, US
Shreyas Mahimkar - Quincy MA, US

G06F 16/78
H04N 21/45
H04N 21/482
H04N 21/442
H04N 21/44
G06F 16/58
H04N 21/4223
H04N 21/47
G06V 10/75
G06V 20/00

Systems and methods are described for disambiguating user input based on a physical location of items in a vicinity of a user. The system determines that a query received from a user contains an ambiguity. In response, the system identifies several items in the physical vicinity of the user. Then, the system analyzes the identified plurality of items to determine whether the plurality of items forms a first ensemble of items or a second ensemble of items. If the plurality of items forms a first ensemble of items, the system performs a search using the search query and a first keyword related to the first ensemble of items. If the plurality of items forms a second ensemble of items, the system performs a search using the search query and a second keyword related to the second ensemble of items. The system then outputs results of the performed search.

2023007, Mar 16, 2023

May 20, 2022

17/664331

- Cambridge MA, US
Michael G. Merideth - Carrboro NC, US
Nil Alexandrov - Cambridge MA, US
Andrew F. Champagne - Ware MA, US
Brendan Coyle - Sudbury MA, US
Timothy Glynn - Malden MA, US
Mark A. Roman - Arlington MA, US
Xin Xu - Waltham MA, US

Akamai Technologies, Inc. - Cambridge MA

H04L 67/568
H04L 67/02
H04L 67/01
H04L 67/566

This patent document describes technology for providing real-time messaging and entity update services in a distributed proxy server network, such as a CDN. Uses include distributing real-time notifications about updates to data stored in and delivered by the network, with both high efficiency and locality of latency. The technology can be integrated into conventional caching proxy servers providing HTTP services, thereby leveraging their existing footprint in the Internet, their existing overlay network topologies and architectures, and their integration with existing traffic management components.

2021026, Aug 26, 2021

Mar 15, 2021

17/201669

- San Jose CA, US
Xin Xu - Reading MA, US
Shreyas Mahimkar - Quincy MA, US

G06F 16/78
G06K 9/00
H04N 21/45
H04N 21/482
H04N 21/442
G06K 9/62
H04N 21/44
G06F 16/58
H04N 21/4223
H04N 21/47

Systems and methods are described for disambiguating user input based on a physical location of items in a vicinity of a user. The system determines that a query received from a user contains an ambiguity. In response, the system identifies several items in the physical vicinity of the user. Then, the system analyzes the identified plurality of items to determine whether the plurality of items forms a first ensemble of items or a second ensemble of items. If the plurality of items forms a first ensemble of items, the system performs a search using the search query and a first keyword related to the first ensemble of items. If the plurality of items forms a second ensemble of items, the system performs a search using the search query and a second keyword related to the second ensemble of items. The system then outputs results of the performed search.

2019031, Oct 10, 2019

Dec 28, 2018

16/235289

- San Jose CA, US
Xin Xu - Reading MA, US
Shreyas Mahimkar - Quincy MA, US

G06F 16/78
H04N 21/482
H04N 5/445
G06K 9/00
H04N 21/45

Systems and methods are described for disambiguating user input based on a physical location of items in a vicinity of a user. The system determines that a query received from a user contains an ambiguity. In response, the system identifies several items in the physical vicinity of the user. Then, the system analyzes the identified plurality of items to determine whether the plurality of items forms a first ensemble of items or a second ensemble of items. If the plurality of items forms a first ensemble of items, the system performs a search using the search query and a first keyword related to the first ensemble of items. If the plurality of items forms a second ensemble of items, the system performs a search using the search query and a second keyword related to the second ensemble of items. The system then outputs results of the performed search.

2018033, Nov 22, 2018

Nov 18, 2016

15/777750

- Philadelphia PA, US
Wei-Heng Shih - Bryn Mawr PA, US
Christopher Emery - Swedesboro NJ, US
Xin Xu - Malden MA, US
Suresh Joshi - Secane PA, US
Wei Wu - Philadelphia PA, US

Drexel University - Philadelphia PA

G01N 29/12

A system for and method of antimicrobial susceptibility testing includes detecting a resonance peak of a sensor provided with live microbes on a surface thereof; applying a substance to the live microbes; detecting a resonance peak of said sensor after application of said substance; determining a width of a top of each of said resonance peaks before and after application of the substance from one of: (1) a phase angle versus frequency plot where the phase angle is the phase angle of the electrical impedance of said sensor, (2) a real part of a plot of an electrical impedance versus frequency of said sensor, (3) a plot of a magnitude of electrical impedance versus frequency of said sensor, and (4) a phase angle versus frequency plot where the phase angle is the phase angle between an output voltage and an input voltage of said sensor, and comparing the determined widths of tops of said resonance peaks or standard deviations of the frequency of said resonance peaks to determine antimicrobial susceptibility including the minimum inhibitory concentration (MIC).

2018000, Jan 4, 2018

Aug 29, 2017

15/689232

- Redwood Shores CA, US
Haobo He - Shenzhen City, CN
Greg Ma - Shanghai, CN
Xin Xu - Westford MA, US

Oracle International Corporation - Redwood Shores CA

G06F 17/30
G06N 99/00
G06F 9/445
G06F 11/00
G06F 9/54
H04L 12/24
G06F 3/0484

Disclosed is a system, method, and computer program product for implementing a log analytics method and system that can configure, collect, and analyze log records in an efficient manner. An improved approach is provided for identifying log files that have undergone a change in status that would require retrieve of its log data, by including a module directly into the operating system that allows the log collection component to be reactively notified of any changes to pertinent log files.