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Yang Zhou, 36Irvine, CA

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Irvine, CA   

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Apple Valley, MN   

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Yang Zhou - Lawyer

Address:
Zhong Lun Law Firm
216-0613658 (Office)
Licenses:
New York - Currently registered 2007
Education:
University of Washington School of Law

Publications & IP owners

Us Patents

Engineered Gamma Delta T Cells And Methods Of Making And Using Thereof

US Patent:
2022021, Jul 7, 2022
Filed:
Dec 28, 2021
Appl. No.:
17/563482
Inventors:
- Oakland CA, US
Derek Lee - Los Angeles CA, US
Yang Zhou - Los Angeles CA, US
Zhe Li - Los Angeles CA, US
Assignee:
The Regents of the University of California - Oakland CA
International Classification:
A61K 35/17
C12N 5/0783
C12N 15/86
C12N 15/62
A61K 38/17
Abstract:
Aspects of the present disclosure relate to methods and compositions related to the preparation of immune cells, including engineered T cells comprising at least one exogenous γδ T cell receptor, for example one that is selected to target a specific disease or pathogen (e.g., cancer or COVID-19). The T cells may be produced from human hematopoietic stem/progenitor cells and are suitable for allogeneic cellular therapy because they do not induce graft-versus-host disease (GvHD) and resist host immune allorejection. Consequently, such cells are suitable for off-the-shelf use in clinical therapy.

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