Yanxia Li, 49Pleasanton, CA

8263079, Sep 11, 2012

Mar 28, 2011

13/073004

Jacqueline Francoise Doody - Ozone Park NY, US
Yanxia Li - Floral Park NY, US

ImClone, LLC - Indianapolis IN

A61K 39/395
C12P 21/08

4241431, 4241421

The invention provides a human antibody that binds human CSF-1R with high affinity. Antibodies of the present invention have significant advantages over the antibodies known in the art by being multifunctional: inhibiting signaling of CSF-1R, internalizing and inducing CSF-1R degradation and stimulating ADCC in cell including tumors, macrophages and monocytes. They are also shown to be effective in treating leukemia, breast, endometrial and prostate cancer alone or in combination with docetaxel, paclitaxel, Herceptin or doxorubicin.

2004022, Nov 11, 2004

Nov 19, 2003

10/718258

Robert Tornoe - Sunol CA, US
Yanxia Li - Pleasanton CA, US
Paul Krzeminski - San Mateo CA, US
Edmund Davies - Orinda CA, US
Leroy Higgins - Newark CA, US
Gordon Lavering - Belmont CA, US

Communications & Power Industries, Inc.,

H01J025/34

315/003500

An electrode structure for a vacuum tube is formed by having a ceramic insulating body act as the tube wall. Electrode areas are formed on the inside of the tube by coating the inside of the tube wall with a conductor. These electrode areas are then coupled, as necessary, to external electronic circuits. The coupling may be performed by through-wall connections, metallized abutting connections and other conventional means. The ceramic insulating body may be generally cylindrical in shape and may be formed of a material such as aluminum nitride, beryllium oxide, aluminum oxide and the like.

2006009, May 4, 2006

Nov 4, 2004

10/982192

Heinz Bohlen - Kehl, DE
Yanxia Li - Pleasanton CA, US
Paul Krzeminski - San Mateo CA, US
Edmund Davies - Orinda CA, US
Robert Tornoe - Sunol CA, US

H05H 13/00

315502000

An inductive output tube (IOT) operates in a frequency range above 1000 MHz. An output window may be provided to separate a vacuum portion of the IOT from an atmospheric pressure portion of the IOT, the output window being surrounded by a cooling air manifold, the manifold including an air input port and a plurality of apertures permitting cooling air to move from the port, through the manifold and into the atmospheric pressure portion of the IOT. The output cavity may include a liquid coolant input port; a lower circular coolant channel coupled to receive liquid coolant from the liquid coolant input port; a vertical coolant channel coupled to receive liquid coolant from the lower circular coolant channel; an upper circular coolant channel coupled to receive liquid coolant from the vertical coolant channel; and a liquid coolant exhaust port coupled to receive liquid coolant from the upper circular coolant channel.

2007008, Apr 12, 2007

Dec 4, 2006

11/633850

Heinz Bohlen - Kehl, DE
Yanxia Li - Pleasanton CA, US
Paul Krzeminski - San Mateo CA, US
Edmund Davies - Orinda CA, US
Robert Tornoe - Sunol CA, US

Communications & Power Industries, Inc. - Palo Alto CA

H01P 7/06

333227000

An inductive output tube (IOT) operates in a frequency range above 1000 MHz. An output window may be provided to separate a vacuum portion of the IOT from an atmospheric pressure portion of the IOT, the output window being surrounded by a cooling air manifold, the manifold including an air input port and a plurality of apertures permitting cooling air to move from the port, through the manifold and into the atmospheric pressure portion of the IOT. The output cavity may include a liquid coolant input port; a lower circular coolant channel coupled to receive liquid coolant from the liquid coolant input port; a vertical coolant channel coupled to receive liquid coolant from the lower circular coolant channel; an upper circular coolant channel coupled to receive liquid coolant from the vertical coolant channel; and a liquid coolant exhaust port coupled to receive liquid coolant from the upper circular coolant channel.