Yanyan Zhang, 43Spring, TX

2015029, Oct 22, 2015

Feb 21, 2013

14/379486

- Indianapolis IN, US
- Oakland CA, US
Yanyan Zhang - Houston TX, US

C12N 15/89
B01J 19/00

Many applications in cell biology, genetic engineering, cell-based therapeutics, and drug discovery require precise and safe methods for introducing membrane-impermeable molecules into cells. This can be implemented satisfactorily by microinjection. However, disadvantages of traditional manual microinjection include high degree of operator skill, low throughput and labor-intensiveness. Many studies have focused on developing automated and high-throughput systems for microinjection to address these limitations. However, none have provided sufficient throughput for applications such as ex vivo cell therapy, where manipulation of many cells is helpful.

2015029, Oct 15, 2015

Apr 9, 2014

14/248553

- Sugar Land TX, US
Jun Zheng - Missouri City TX, US
Yanyan Zhang - Missouri City TX, US

Applied Optoelectronics, Inc. - Sugar Land TX

H01S 5/062
H04J 14/02
H04B 10/50
H01S 5/068
H01S 5/024

A tunable laser with multiple in-line sections generally includes a semiconductor laser body with a plurality of in-line laser sections each configured to be driven independently to generate laser light at a wavelength within a different respective wavelength range. The wavelength of the light generated in each of the laser sections may be tuned, in response to a temperature change, to a channel wavelength within the respective wavelength range. A switch module may be configured to couple a signal from a laser driver to a selected one of the plurality of in-line laser sections, wherein the signal modulates the laser light generated by the in-line laser section. The selected in-line section may be DC biased to a lasing state and the non-selected in-line sections may be DC biased to a non-lasing or transparent state.