Yong Z Quan, 5613333 Sanford Ave, Flushing, NY 11355

2002015, Oct 17, 2002

Dec 11, 2001

10/015498

Kelli Smith - Fairlawn NJ, US
Yong Quan - East Windsor NJ, US

C07H021/04

536/023500

This invention provides a recombinant nucleic acid comprising a nucleic acid encoding a mammalian SNORF49 receptor, wherein the mammalian receptor-encoding nucleic acid hybridizes under high stringency conditions to a nucleic acid encoding a human SNORF49 receptor and having a sequence identical to the sequence of the human SNORF49 receptor-encoding nucleic acid contained in plasmid pEXJ.T73BS-hSNORF49-f (Patent Deposit Designation PTA-659). This Invention further provides a recombinant nucleic acid comprising a nucleic acid encoding a human SNORF49 receptor, wherein the human SNORF49 receptor comprises an amino acid sequence identical to the sequence of the human SNORF49 receptor encoded by the shortest open reading frame indicated in FIGS. 1A-1B (SEQ ID NO: 1).

2003010, Jun 5, 2003

Aug 26, 2002

10/228667

Kelli Smith - Wayne NJ, US
Yong Quan - East Windsor NJ, US

C07H021/04

536/023500

This invention provides a recombinant nucleic acid comprising a nucleic acid encoding a mammalian SNORF65 receptor, wherein the mammalian receptor-encoding nucleic acid hybridizes under high stringency conditions to a nucleic acid encoding a human SNORF65 receptor and having a sequence identical to the sequence of the human SNORF65 receptor-encoding nucleic acid contained in plasmid pEXJ.T3T7-hSNORF65-f (Patent Deposit Designation No. PTA 1226). This invention further provides a recombinant nucleic acid comprising a nucleic acid encoding a human SNORF65 receptor, wherein the human SNORF65 receptor comprises an amino acid sequence identical to the sequence of the human SNORF65 receptor encoded by the shortest open reading frame indicated in FIGS. A-B (SEQ ID NO: 1).

7029857, Apr 18, 2006

Jun 30, 2000

09/609146

James A. Bonini - Oakland NJ, US
Gabriel S. Lerman - Teaneck NJ, US
Kristine L. Ogozalek - Rochelle Park NJ, US
Yong Quan - Fords NJ, US

H. Lundbeck A/S - Valby-Copenhagen

G01N 33/53
C12N 5/10

435 71, 435 72, 435325, 435348, 435357, 435361, 435356, 435365, 435369, 435354, 4353201, 530356, 536 235

This invention provides isolated nucleic acids encoding mammalian SNORF62 and SNORF72 receptors, purified mammalian SNORF62 and SNORF72 receptors, vectors comprising nucleic acid encoding mammalian SNORF62 and SNORF72 receptors, cells comprising such vectors, antibodies directed to mammalian SNORF62 and SNORF72 receptors, nucleic acid probes useful for detecting nucleic acid encoding mammalian SNORF62 and SNORF72 receptors, antisense oligonucleotides complementary to unique sequences of nucleic acid encoding mammalian SNORF62 and SNORF72 receptors, transgenic, nonhuman animals which express DNA encoding normal or mutant mammalian SNORF62 and SNORF72 receptors, methods of isolating mammalian SNORF62 and SNORF72 receptors, methods of treating an abnormality that is linked to the activity of the mammalian SNORF62 and SNORF72 receptors, as well as methods of determining binding of compounds to mammalian SNORF62 and SNORF72 receptors, methods of identifying agonists and antagonists of SNORF62 and SNORF72 receptors, and agonists and antagonists so identified. This invention also provides methods of treating an abnormality that is linked to the activity of a mammalian NMU receptor, as well as methods of determining binding of compounds to mammalian NMU receptors, methods of identifying agonists and antagonists of NMU receptors, and agonists and antagonists so identified.