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Yongfeng Y Li, 4122419 Bridgehaven Dr, Katy, TX 77494

Yongfeng Li Phones & Addresses

22419 Bridgehaven Dr, Katy, TX 77494    281-5745515   

Houston, TX   

Minneapolis, MN   

Atlanta, GA   

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Yongfeng Y Li

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Company: Downunder geosolutions Position: Geophysicist

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Oil & Energy

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Yongfeng Li resumes & CV records

Resumes

Yongfeng Li Photo 15

Geophysicist

Location:
Houston, TX
Industry:
Oil & Energy
Work:
Downunder Geosolutions
Geophysicist

Publications & IP owners

Us Patents

Preparation Of Synthetic Nucleosides Via Pi-Allyl Transition Metal Complex Formation

US Patent:
2010020, Aug 12, 2010
Filed:
Feb 3, 2010
Appl. No.:
12/699322
Inventors:
Dennis C. Liotta - Atlanta GA, US
Yongfeng Li - Marietta GA, US
International Classification:
C07H 19/06
C07D 473/18
US Classification:
536 285, 544276
Abstract:
This invention provides highly regioselective and stereoselective processes for preparing synthetic nucleosides. A process for the preparation of synthetic nucleosides is provided that comprises a) preparing a bicycloamide derivative, b) reacting the bicycloamide derivative with a nucleic acid base or heterocyclic base or salt thereof in the presence of a transition metal catalyst to form a cyclopentenecarboxamide, and c) cleaving a carboxamide group from the cyclopentenecarboxamide to form the synthetic nucleoside. The processes according to the invention can be used for the synthesis of a variety of anti-viral agents, including Abacavir, Carbovir, and Entecavir, as well as derivatives thereof.

Carbapenem Antibacterials With Gram-Negative Activity

US Patent:
2013017, Jul 4, 2013
Filed:
Dec 13, 2012
Appl. No.:
13/713520
Inventors:
FOB Synthesis, Inc. - Kennesaw GA, US
Shuli MAO - Atlanta GA, US
Yongfeng LI - Marietta GA, US
Assignee:
FOB SYNTHESIS, INC. - Kennesaw GA
International Classification:
A61K 31/407
A61K 45/06
C07D 477/16
US Classification:
51421009, 540302
Abstract:
The present invention provides β-methyl carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections and methods for treating such infections using such compounds and/or compositions. The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment.

Fluorescent Nucleoside Analogues

US Patent:
2010011, May 6, 2010
Filed:
Aug 27, 2007
Appl. No.:
12/310455
Inventors:
Stefan Lutz - Tucker GA, US
Dennis Liotta - Atlanta GA, US
Yongfeng Li - Marietta GA, US
International Classification:
C12Q 1/68
C07H 19/06
C07H 19/00
C07H 19/22
US Classification:
435 6, 536 284, 536 272, 536 2713
Abstract:
Briefly described, embodiments of the present disclosure include novel fluorescent nucleoside analogs (fNAs) including a fluorescent nucleobase, selected from a purine and a pyrimidine base or analog thereof, and a modified sugar moiety that differs in structure from a sugar moiety of a naturally occurring nucleoside. In embodiments, the fNAs of the present disclosure are analogues of NA prodrugs used to treat viral disorders. Embodiments of the present disclosure also include methods of making the novel fNAs of the present disclosure.

Carbapenem Antibacterials With Gram-Negative Activity

US Patent:
2015030, Oct 29, 2015
Filed:
Apr 22, 2015
Appl. No.:
14/692973
Inventors:
- Kennesaw GA, US
Shuli Mao - Atlanta GA, US
Yongfeng Li - Marietta GA, US
International Classification:
A61K 31/407
A61K 45/06
Abstract:
The present invention provides β-methyl carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections and methods for treating such infections using such compounds and/or compositions. The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment.

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