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Alexander M Porte, 54Madison, CT

Known as:
Alex M Porte Alexander M Prote Alexander Parte Michael Porte Alexander
Related to:
Alexander C Elliott 36

Alexander Porte Phones & Addresses

Madison, CT   

Groton, CT   

26 Avalon Rd, Pennington, NJ 08534    609-7370751   

Monmouth Junction, NJ   

6 Asbury Ave, Woburn, MA 01801    781-9389093    781-9388984   

2 Westgate Dr, Woburn, MA 01801   

Plainsboro, NJ   

College Station, TX   

Grand Rapids, MI   

Middletown, CT   

Vernon Rockville, CT   

6 Asbury Ave, Woburn, MA 01801   

Work

Position: Protective Service Occupations

Emails

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Mentions for Alexander M Porte

Publications & IP owners

Us Patents

Amino-5-[4-(Difluoromethoxy)Phenyl]-5-Phenylimidazolone Compounds For The Inhibition Of Beta-Secretase

US Patent:
7723368, May 25, 2010
Filed:
Mar 21, 2008
Appl. No.:
12/053086
Inventors:
Michael Sotirios Malamas - Jamison PA, US
Albert Jean Robichaud - Ringoes NJ, US
Alexander Michael Porte - Pennington NJ, US
Koi Michele Morris - Plainsboro NJ, US
William R. Solvibile - East Windsor NJ, US
Ji-In Kim - Princeton NJ, US
Schuyler Adam Antane - Princeton Junction NJ, US
Assignee:
Wyeth LLC - Madison NJ
International Classification:
A61K 31/4166
A61K 31/4168
C07D 233/30
US Classification:
514386, 5483215
Abstract:
The present invention provides compounds and methods for the use thereof to inhibit β-secretase (BACE) and treat β-amyloid deposits and neurofibrillary tangles.

Trifluoromethyl-Containing Phenylsulfonamide Beta Amyloid Inhibitors

US Patent:
2007024, Oct 25, 2007
Filed:
Apr 19, 2007
Appl. No.:
11/788349
Inventors:
Alexander Michael Porte - Pennington NJ, US
Thomas Joseph Caggiano - Morrisville PA, US
George Diamantidis - Randolph NJ, US
Diane Barbara Hauze - Radnor PA, US
Boyd Lynn Harrison - Princeton Junction NJ, US
Molly Hoke - Hightstown NJ, US
Anthony Kreft - Langhorne PA, US
Dennis M. Kubrak - Philadelphia PA, US
Charles William Mann - Philadelphia PA, US
Scott Mayer - Bridgewater NJ, US
Koi Michele Morris - Plainsboro NJ, US
Assignee:
Wyeth - Madison NJ
International Classification:
A61K 31/18
C07C 309/30
US Classification:
514602, 564 86
Abstract:
A compound of Formula (I), or pharmaceutically acceptable salts and/or hydrates or prodrugs thereof, wherein Formula (I) has the structure:is provided, wherein R-Rare defined herein. These compounds are useful in medicaments for treating a disease selected from the group consisting of Alzheimer's Disease, amyloid angiopathy, cerebral amyloid angiopathy, systemic amyloidosis, hereditary cerebral hemorrhage with amyloidosis of the Dutch type, inclusion body myositis, mild cognitive impairment (MCI) and Down's syndrome, in a subject.

Amino-5-[Substituted-4-(Difluoromethoxy)Phenyl]-5-Phenylimidazolone Compounds As Beta-Secretase Inhibitors

US Patent:
2009004, Feb 12, 2009
Filed:
Mar 20, 2008
Appl. No.:
12/052098
Inventors:
Michael Sotirios Malamas - Jamison PA, US
Albert Jean Robichaud - Ringoes NJ, US
Alexander Michael Porte - Pennington NJ, US
William R. Solvibile - East Windsor NJ, US
Koi Michele Morris - Plainsboro NJ, US
Schuyler Adam Antane - Princeton Junction NJ, US
Ji-In Kim - Princeton NJ, US
Robert Emmett McDevitt - Freehold NJ, US
Assignee:
Wyeth - Madison NJ
International Classification:
A61K 31/4168
C07D 233/32
A61P 25/00
US Classification:
514386, 5483215
Abstract:
The present invention provides a 2-amino-5-[substituted-4-(difluoromethoxy)phenyl]-5-phenylimidazolone compound of formula IThe present invention also provides methods for the use thereof to inhibit β-secretase (BACE) and treat β-amyloid deposits and neurofibrillary tangles.

Trifluoromethyl-Containing Phenylsulfonamide Beta Amyloid Inhibitors

US Patent:
2009022, Sep 3, 2009
Filed:
May 12, 2009
Appl. No.:
12/464155
Inventors:
Alexander Michael Porte - Pennington NJ, US
Thomas Joseph Caggiano - Morrisville PA, US
George Diamantidis - Randolph NJ, US
Diane Barbara Hauze - Radnor PA, US
Boyd Lynn Harrison - Princeton Junction NJ, US
Molly Hoke - Hightstown NJ, US
Anthony Kreft - Langhorne PA, US
Dennis M. Kubrak - Philadelphia PA, US
Charles William Mann - Philadelphia PA, US
Scott Mayer - Bridgewater NJ, US
Koi Michele Morris - Plainsboro NJ, US
Assignee:
Wyeth - Madison NJ
International Classification:
A61K 31/18
C07C 311/29
A61P 25/28
US Classification:
514603, 564 93, 514604
Abstract:
A compound of Formula (I), or pharmaceutically acceptable salts and/or hydrates or prodrugs thereof, wherein Formula (I) has the structure:is provided, wherein R-Rare defined herein. These compounds are useful in medicaments for treating a disease selected from the group consisting of Alzheimer's disease, amyloid angiopathy, cerebral amyloid angiopathy, systemic amyloidosis, hereditary cerebral hemorrhage with amyloidosis of the Dutch type, inclusion body myositis, mild cognitive impairment (MCI) and Down's syndrome, in a subject.

Amino-5-[4-(Difluoromethoxy)Phenyl]-5-Phenylimidazolone Compounds For The Inhibition Of Beta-Secretase

US Patent:
2010016, Jul 1, 2010
Filed:
Mar 10, 2010
Appl. No.:
12/721086
Inventors:
Michael Sotirios Malamas - Jamison PA, US
Albert Jean Robichaud - Ringoes NJ, US
Alexander Michael Porte - Pennington NJ, US
Koi Michele Morris - Plainsboro NJ, US
William R. Solvibile - East Windsor NJ, US
Ji-In Kim - Princeton NJ, US
Schuyler Adam Antane - Princeton Juncton NJ, US
Assignee:
Wyeth LLC - Madison NJ
International Classification:
A61K 31/4166
C07D 233/30
A61P 25/28
US Classification:
514391, 5483215
Abstract:
The present invention provides compounds and methods for the use thereof to inhibit β-secretase (BACE) and treat β-amyloid deposits and neurofibrillary tangles.

Bifunctional Cytotoxic Agents

US Patent:
2018033, Nov 29, 2018
Filed:
Aug 2, 2018
Appl. No.:
16/053344
Inventors:
- New York NY, US
Matthew David DOROSKI - Mystic CT, US
Zecheng CHEN - New City NY, US
Hud Lawrence RISLEY - Baltic CT, US
Jeffrey Michael CASAVANT - Franklin CT, US
Christopher John O'DONNELL - Mystic CT, US
Alexander M. PORTE - Madison CT, US
Chakrapani SUBRAMANYAM - South Glastonbury CT, US
Assignee:
PFIZER INC. - New York NY
International Classification:
A61K 47/68
C07K 9/00
C07K 5/06
C07H 17/02
C07F 9/6561
C07D 487/04
C07D 417/14
C07D 409/14
C07D 405/14
C07D 401/14
A61K 38/06
A61K 38/05
A61K 31/7056
A61K 31/675
A61K 31/454
A61K 31/4439
A61K 31/433
A61K 31/407
A61K 31/404
C07K 5/08
Abstract:
Cytotoxic dimers comprising CBI-based and/or CPI-based sub-units, antibody drug conjugates comprising such dimers, and to methods for using the same to treat cancer and other conditions.

Bifunctional Cytotoxic Agents

US Patent:
2015020, Jul 30, 2015
Filed:
Jan 26, 2015
Appl. No.:
14/605697
Inventors:
- New York NY, US
Matthew David DOROSKI - Mystic CT, US
Zecheng CHEN - New City NY, US
Hud Lawrence RISLEY - Baltic CT, US
Jeffrey Michael CASAVANT - Franklin CT, US
Christopher John O'DONNELL - Mystic CT, US
Alexander M. PORTE - Madison CT, US
Chakrapani SUBRAMANYAM - South Glastonbury CT, US
International Classification:
A61K 47/48
A61K 31/404
A61K 31/4439
C07D 401/14
C07D 409/14
A61K 31/675
C07F 9/6561
A61K 31/454
A61K 31/7056
C07H 17/02
C07D 417/14
A61K 31/433
A61K 31/407
C07D 487/04
C07K 5/08
C07K 5/06
C07K 9/00
A61K 38/05
A61K 38/06
C07D 405/14
Abstract:
Cytotoxic dimers comprising CBI-based and/or CPI-based sub-units, antibody drug conjugates comprising such dimers, and to methods for using the same to treat cancer and other conditions.

Possible Relatives

Evelyn M Porte  Jeffrey P Porte  Rawle E Porte  Vivian B Porte  Alex M Porte  Alexander B Johnson  Alexander B Johnston  Alexander White  Alexander W Jones  Alexander Stanley 

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