Aurelio H Valencia, 593147 Loretta Way, Santa Rosa, CA 95403

6994700, Feb 7, 2006

Mar 18, 2005

11/084295

Jeffrey M. Elkins - Novato CA, US
Harry B. Goodson - Fremont CA, US
Mark A. Maguire - San Mateo CA, US
Aurelio Valencia - East Palo Alto CA, US
Samir R. Patel - Mountain View CA, US

Flowmedica, Inc. - Fremont CA

A61M 25/01

604528, 604523

An introducer system delivers therapy locally to a renal system in a patient. A proximal coupler assembly is coupled to an introducer sheath that delivers multiple devices simultaneously into a location within an abdominal aorta associated with first and second renal artery ostia. The coupler assembly has a network of branch lumens arranged to allow for smooth slideable engagement of multiple coupled devices without substantial interference therebetween. A first branch lumen typically introduces a percutaneous translumenal interventional device such as an angiography or guiding catheter into the introducer sheath and is substantially aligned with a longitudinal axis of the sheath. One or more other branch lumen are off-axis from the longitudinal axis by about 30 degrees or less and introduce components of a bilateral renal delivery assembly into the introducer sheath in conjunction with the other device. Novel insertion devices are provided to coordinate the coupling of the multiple devices.

7104981, Sep 12, 2006

Oct 25, 2005

11/259187

Jeffrey M. Elkins - Novato CA, US
Harry B. Goodson - Fremont CA, US
Mark A. Maguire - San Mateo CA, US
Aurelio Valencia - East Palo Alto CA, US
Samir R. Patel - Mountain View CA, US

FlowMedica, Inc. - Fremont CA

A61M 25/01

604528, 604 501

An introducer system delivers therapy locally to a renal system in a patient. A proximal coupler assembly is coupled to an introducer sheath that delivers multiple devices simultaneously into a location within an abdominal aorta associated with first and second renal artery ostia. The coupler assembly has a network of branch lumens arranged to allow for smooth slideable engagement of multiple coupled devices without substantial interference therebetween. A first branch lumen typically introduces a percutaneous translumenal interventional device such as an angiography or guiding catheter into the introducer sheath and is substantially aligned with a longitudinal axis of the sheath. One or more other branch lumen are off-axis from the longitudinal axis by about 30 degrees or less and introduce components of a bilateral renal delivery assembly into the introducer sheath in conjunction with the other device. Novel insertion devices are provided to coordinate the coupling of the multiple devices.

7364566, Apr 29, 2008

Mar 18, 2005

11/084434

Jeffrey M. Elkins - Novato CA, US
Aurelio Valencia - East Palo Alto CA, US
Samir R. Patel - Mountain View CA, US
Ricardo Aboytes - East Palo Alto CA, US
Harry B. Goodson - Fremont CA, US
Craig A. Ball - San Carlos CA, US

FlowMedica, Inc. - Fremont CA

A61M 29/00
A61M 25/00

604104, 604523

A renal flow system injects a volume of fluid agent into a location within an abdominal aorta in a manner that flows bi-laterally into each of two renal arteries via their respectively spaced ostia along the abdominal aorta wall. A local injection assembly includes two injection members, each having an injection port that couples to a source of fluid agent externally of the patient. The injection ports may be positioned with an outer region of blood flow along the abdominal aorta wall perfusing the two renal arteries. A flow isolation assembly may isolate flow of the injected agent within the outer region and into the renals. The injection members are delivered to the location in a first radially collapsed condition, and bifurcate across the aorta to inject into the spaced renal ostia. A delivery catheter for upstream interventions is used as a chassis to deliver a bilateral local renal injection assembly to the location within the abdominal aorta.

7914503, Mar 29, 2011

Mar 16, 2005

11/084738

Jeffrey M. Elkins - Novato CA, US
Samir R. Patel - Mountain View CA, US
Aurelio Valencia - East Palo Alto CA, US
Ricardo Aboytes - East Palo Alto CA, US
Craig A. Ball - San Carlos CA, US
Randy J. Kesten - Mountain View CA, US
Andrew W. Kramer - Los Gatos CA, US
Sam G. Payne - Santa Clara CA, US
Sophia Pesotchinsky - Los Altos Hills CA, US
Michael H. Rosenthal - Palo Alto CA, US

Angio Dynamics - Latham NY

A61M 25/00
A61M 29/00

604264, 604 9601

Two renal delivery members have two distal ports that are adapted to be positioned within two renal arteries via their corresponding renal ostia at unique locations along an abdominal aortic wall. A proximal coupler assembly is outside the body and is coupled to deliver material to the two distal ports for bi-lateral renal therapy. One or both of the delivery members may be self-cannulating into the corresponding renal ostium, or may be controllably steered into the respective ostium. Non-occlusive anchors may be coupled with one or both of the delivery members at anchoring positions in the renal artery or abdominal aorta to secure the renal delivery member within the renal artery. Renal-active fluid agents are coupled to the bi-lateral delivery system. Another renal therapy system cannulates a renal vein from the vena cava and controls a retrograde delivery of agents to the respective kidney.

8012121, Sep 6, 2011

Jun 26, 2007

11/768390

Jeffrey M. Elkins - Novato CA, US
Samir R. Patel - Mountain View CA, US
Aurelio Valencia - East Palo Alto CA, US
Ricardo Aboytes - East Palo Alto CA, US
Craig A. Ball - San Carlos CA, US
Randy J. Kesten - Mountain View CA, US
Andrew K. Kramer - Los Gatos CA, US
Sam G. Payne - Santa Clara CA, US
Sophia Pesotchinsky - Los Altos Hills CA, US
Michael H. Rosenthal - Palo Alto CA, US

AngioDynamics, Inc. - Latham NY

A61M 31/00
A61F 2/06

604 9301, 623 135

Two renal delivery members have two distal ports that are adapted to be positioned within two renal arteries via their corresponding renal ostia at unique locations along an abdominal aortic wall. A proximal coupler assembly is outside the body and is coupled to deliver material to the two distal ports for bi-lateral renal therapy. One or both of the delivery members may be self-cannulating into the corresponding renal ostium, or may be controllably steered into the respective ostium. Non-occlusive anchors may be coupled with one or both of the delivery members at anchoring positions in the renal artery or abdominal aorta to secure the renal delivery member within the renal artery. Renal-active fluid agents are coupled to the bi-lateral delivery system. Another renal therapy system cannulates a renal vein from the vena cava and controls a retrograde delivery of agents to the respective kidney.

8585678, Nov 19, 2013

Mar 7, 2008

12/044230

Jeffrey M. Elkins - Novato CA, US
Aurelio Valencia - East Palo Alto CA, US
Samir R. Patel - Mountain View CA, US
Ricardo Aboytes - East Palo Alto CA, US
Harry B. Goodson - Fremont CA, US
Craig A. Ball - San Carlos CA, US

AngioDynamics, Inc. - Latham NY

A61M 31/00

604508

A renal flow system injects a volume of fluid agent into a location within an abdominal aorta in a manner that flows bi-laterally into each of two renal arteries via their respectively spaced ostia along the abdominal aorta wall. A local injection assembly includes two injection members, each having an injection port that couples to a source of fluid agent externally of the patient. The injection ports may be positioned with an outer region of blood flow along the abdominal aorta wall perfusing the two renal arteries. A flow isolation assembly may isolate flow of the injected agent within the outer region and into the renals. The injection members are delivered to the location in a first radially collapsed condition, and bifurcate across the aorta to inject into the spaced renal ostia. A delivery catheter for upstream interventions is used as a chassis to deliver a bilateral local renal injection assembly to the location within the abdominal aorta.

7993325, Aug 9, 2011

Sep 29, 2005

11/241749

Jeffrey M. Elkins - Novato CA, US
Craig A Ball - San Carlos CA, US
Aurelio Valencia - East Palo Alto CA, US
Samir R Patel - Mountain View CA, US
Neema Hekmat - Mountain View CA, US

Angio Dynamics, Inc. - Latham NY

A61M 31/00

604508, 604284

Systems, devices, and methods for delivering treatment to the renal arteries are provided. Exemplary systems include a delivery catheter having a distal bifurcation, an introducer assembly comprising an introducer sheath in operative association with a Y-hub, wherein Y-hub includes a first port for receiving the delivery catheter and a second port for receiving a second catheter, and a constraint assembly for holding the distal bifurcation of the delivery catheter in a low-profile configuration when it is advanced distally beyond the introducer sheath.

2006006, Mar 30, 2006

Sep 22, 2005

11/233562

Jeffrey Elkins - Novato CA, US
Harry Goodson - Fremont CA, US
Aurelio Valencia - East Palo Alto CA, US
Richard Aboytes - East Palo Alto CA, US
Samir Patel - Mountain View CA, US

FlowMedica, Inc. - Fremont CA

A61M 25/00

600585000

A system and method is provided that is adapted to allow for rapid cannulation of a guidewire into a branch lumen extending from a main lumen in a body of a patient, and in particular into two renal arteries extending from an abdominal aorta wall. A dual lumen catheter shaft delivers first and second pre-shaped guidewires to the location of the renal arteries in the aorta, such that the first and second pre-shaped guidewires self-cannulate within the renal arteries. Additional guidewires and/or interventional devices may be incorporated into the system and method for use with the catheter shaft, or over the two pre-shaped guidewires, to meet a particular need for a particular patient or intended procedure.