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Bruce Wayne Partridge, 711117 N Franklin Ave, Springfield, IL 62702

Bruce Partridge Phones & Addresses

1117 N Franklin Ave, Springfield, IL 62702    217-7878497   

1219 S Macarthur Blvd, Springfield, IL 62704    217-7878497   

North Las Vegas, NV   

Cantrall, IL   

Trenton, MI   

Lincoln, NE   

Rio Rico, AZ   

Lovettsville, VA   

Dallas, TX   

1117 N Franklin Ave, Springfield, IL 62702   

Work

Position: Executive, Administrative, and Managerial

Education

Degree: Bachelor's degree or higher

Emails

Mentions for Bruce Wayne Partridge

Publications & IP owners

Wikipedia

Bruce Partridge Photo 27

The Martlet

In 1971, the Martlet was partly responsible for bringing about the resignation of the university's president, Bruce J. Partridge, when it erroneously reported that he had ...

Us Patents

Enzymatic Method For Modification Of Recombinant Polypeptides

US Patent:
6403361, Jun 11, 2002
Filed:
Feb 17, 2000
Appl. No.:
09/505991
Inventors:
Fred W. Wagner - Walton NE
Jay Stout - Lincoln NE
Dennis Henriksen - Lincoln NE
Bruce Partridge - Lincoln NE
Shane Manning - Lincoln NE
Assignee:
Restoragen, Inc. - Lincoln NE
International Classification:
C12N 120
US Classification:
4352523, 4353201, 435325, 514 2, 530300, 536 234, 536 235
Abstract:
The method of the invention provides for the formation of a recombinant polypeptide which has been modified at the C-terminal end through the use of a transpeptidation process. The method is suitable for modifying recombinant polypeptides of any source including those which may be commercially available, those derived from recombinant single copy or multicopy polypeptide constructs, or those derived from single or multicopy recombinant fusion protein constructs. The transpeptidation reaction involves contacting an endopeptidase enzyme with a recombinant polypeptide to substitute an addition unit, of one or more amino acids, for a leaving unit, linked to a core polypeptide through a cleavage site recognized by the endopeptidase enzyme. Recombinant polypeptides derived from multicopy polypeptide constructs may be cleaved from the multicopy polypeptide at the N-terminal and C-terminal ends and simultaneously under go substitution of the leaving unit by the desired addition unit. The invention utilizes known and newly discovered cleavage recognition sites to effectuate the desired modification products.

Recombinant Preparation Of Calcitonin Fragments And Use Thereof In The Preparation Of Calcitonin And Related Analogs

US Patent:
6410707, Jun 25, 2002
Filed:
Jan 2, 2001
Appl. No.:
09/750913
Inventors:
Fred W. Wagner - Walton NE
Jay S. Stout - Lincoln NE
Dennis B. Henriksen - Lincoln NE
Bruce E. Partridge - Lincoln NE
Bart Holmquist - Lincoln NE
Julie A. Frank - Lincoln NE
Assignee:
BioNebraska, Inc. - Lincoln NE
International Classification:
C07H 2104
US Classification:
536 232, 4352523, 4353201, 435 691, 435 697, 536 231, 536 234, 530300, 530307, 530325, 530350
Abstract:
A process for the recombinant preparation of a calcitonin fragment and the use of the fragment in the preparation of calcitonin and related analogs is provided. The process includes recombinantly forming a fusion protein which includes the calcitonin fragment linked to a carbonic anhydrase. The recombinantly formed fusion protein is subsequently cleaved to produce a polypeptide which includes the calcitonin fragment. A method for producing a calcitonin carba analog which includes condensing a desaminononapeptide with the recombinantly formed calcitonin fragment is also provided.

Production Of C-Terminal Amidated Peptides From Recombinant Protein Constructs

US Patent:
6051399, Apr 18, 2000
Filed:
Sep 19, 1997
Appl. No.:
8/934171
Inventors:
Jay S. Stout - Lincoln NE
Bruce E. Partridge - Lincoln NE
Dennis B. Henriksen - Lincoln NE
Barton Holmquist - Lincoln NE
Fred W. Wagner - Walton NE
Assignee:
BioNebraska, Inc. - Lincoln NE
International Classification:
C12P 2100
C07K 1446
C07H 2104
US Classification:
435 691
Abstract:
A method for the production of C-terminal amidated recombinant peptides is provided. The method employs a recombinant protein construct having multiple copies of a target peptide linked by intraconnecting peptides. The intraconnecting peptides permit the multicopy construct to be selectively reacted to produce product peptides having a C-terminal. alpha. -carboxamide. A recombinant gene containing a DNA sequence coding for the recombinant protein construct and an expression cassette, an expression vector and a transformed cell including the recombinant gene are also provided.

Enzymatic Method For Modification Of Recombinant Polypeptides

US Patent:
5707826, Jan 13, 1998
Filed:
Jun 6, 1995
Appl. No.:
8/470220
Inventors:
Fred W. Wagner - Walton NE
Jay Stout - Lincoln NE
Dennis Henriksen - Lincoln NE
Bruce Partridge - Lincoln NE
Shane Manning - Lincoln NE
Assignee:
BioNebraska, Incorporated - Lincoln NE
International Classification:
C12P 2106
C12P 2102
C12P 2100
C12P 1509
US Classification:
435 681
Abstract:
The method of the invention provides for the formation of a recombinant polypeptide which has been modified at the C-terminal end through the use of a transpeptidation process. The method is suitable for modifying recombinant polypeptides of any source including those which may be commercially available, those derived from recombinant single copy or multicopy polypeptide constructs, or those derived from single or multicopy recombinant fusion protein constructs. The transpeptidation reaction involves contacting an endopeptidase enzyme with a recombinant polypeptide to substitute an addition unit, of one or more amino acids, for a leaving unit, linked to a core polypeptide through a cleavage site recognized by the endopeptidase enzyme. Recombinant polypeptides derived from multicopy polypeptide constructs may be cleaved from the multicopy polypeptide at the N-terminal and C-terminal ends and simultaneously under go substitution of the leaving unit by the desired addition unit. The invention utilizes known and newly discovered cleavage recognition sites to effectuate the desired modification products.

Enzymatic Method For Modification Or Recombinant Polypeptides

US Patent:
5512459, Apr 30, 1996
Filed:
Jul 20, 1993
Appl. No.:
8/095162
Inventors:
Fred W. Wagner - Walton NE
Jay Stout - Lincoln NE
Dennis Henriksen - Lincoln NE
Bruce Partridge - Lincoln NE
Shane Manning - Lincoln NE
Assignee:
BioNebraska, Inc. - Lincoln NE
International Classification:
C12P 2106
C12N 974
C12N 976
C12N 1509
US Classification:
435 681
Abstract:
The method of the invention provides for the formation of a recombinant polypeptide which has been modified at the C-terminal end through the use of a transpeptidation process. The method is suitable for modifying recombinant polypeptides of any source including those which may be commercially available, those derived from recombinant single copy or multicopy polypeptide constructs, or those derived from single or multicopy recombinant fusion protein constructs. The transpeptidation reaction involves contacting an endopeptidase enzyme with a recombinant polypeptide to substitute an addition unit, of one or more amino acids, for a leaving unit, linked to a core polypeptide through a cleavage site recognized by the endopeptidase enzyme. Recombinant polypeptides derived from multicopy polypeptide constructs may be cleaved from the multicopy polypeptide at the N-terminal and C-terminal ends and simultaneously under go substitution of the leaving unit by the desired addition unit. The invention utilizes known and newly discovered cleavage recognition sites to effectuate the desired modification products.

Recombinant Preparation Of Calcitonin Fragments And Use Thereof In The Preparation Of Calcitonin And Related Analogs

US Patent:
5962270, Oct 5, 1999
Filed:
Feb 6, 1996
Appl. No.:
8/595868
Inventors:
Fred W. Wagner - Walton NE
Jay S. Stout - Lincoln NE
Dennis B. Henriksen - Lincoln NE
Bruce E. Partridge - Lincoln NE
Bart Holmquist - Lincoln NE
Julie A. Frank - Lincoln NE
Assignee:
Bionebraska, Inc. - Lincoln NE
International Classification:
C12P 2104
C12P 2106
C12P 2100
US Classification:
435 697
Abstract:
A process for the recombinant preparation of a calcitonin fragment and the use of the fragment in the preparation of calcitonin and related analogs is provided. The process includes recombinantly forming a fusion protein which includes the calcitonin fragment linked to a carbonic anhydrase. The recombinantly formed fusion protein is subsequently cleaved to produce a polypeptide which includes the calcitonin fragment. A method for producing a calcitonin carba analog which includes condensing a desaminononapeptide with the recombinantly formed calcitonin fragment is also provided.

Recombinant Preparation Of Calcitonin Fragments And Use Thereof In The Preparation Of Calcitonin And Related Analogs

US Patent:
6251635, Jun 26, 2001
Filed:
Aug 25, 1998
Appl. No.:
9/139819
Inventors:
Fred W. Wagner - Walton NE
Jay S. Stout - Lincoln NE
Dennis B. Henriksen - Lincoln NE
Bruce E. Partridge - Lincoln NE
Bart Holmquist - Lincoln NE
Julie A. Frank - Lincoln NE
Assignee:
Bionebraska, Inc. - Lincoln NE
International Classification:
C12P 2104
C12P 2106
C12N 120
C12N 1500
A61K 3800
US Classification:
435 697
Abstract:
A process for the recombinant preparation of a calcitonin fragment and the use of the fragment in the preparation of calcitonin and related analogs is provided. The process includes recombinantly forming a fusion protein which includes the calcitonin fragment linked to a carbonic anhydrase. The recombinantly formed fusion protein is subsequently cleaved to produce a polypeptide which includes the calcitonin fragment. A method for producing a calcitonin carba analog which includes condensing a desaminononapeptide with the recombinantly formed calcitonin fragment is also provided.

Treatment Process For Promoting Weight Loss Employing A Substituted .Delta. 5

US Patent:
5296481, Mar 22, 1994
Filed:
Apr 10, 1992
Appl. No.:
7/867288
Inventors:
Bruce E. Partridge - Lincoln NE
Henry A. Lardy - Madison WI
Assignee:
Humanetics Corporation - Chaska MN
International Classification:
A61K 3156
C07J 100
US Classification:
514178
Abstract:
A method for controlling weight gain or promoting weight loss which includes the step of treating a subject with an effective weight gain controlling or weight loss promoting amount of a substituted. DELTA. 5-Androstene which is biologically effective for controlling weight gain or promoting weight loss and biologically ineffective for promoting the synthesis of sex hormones. Steroids believed to provide the desired weight control/weight loss characteristics include:. DELTA. 5-Androstene-3. beta. ,7. alpha. -diol-17-one. DELTA. 5-Androstene-3. beta. -ol-7,17-dione. DELTA. 5-Androstene-3. beta. ,7. alpha. ,17-triol. DELTA. 5-Androstene-3. beta. ,17. beta. -diol-7-one and various derivatives thereof.

Isbn (Books And Publications)

Legal Writing For Understanding, Clarity, And Precision: Materials Prepared For A Continuing Legal Education Seminar Held In Vancouver, B.c. On September 22, 1982

Author:
Bruce J. Partridge
ISBN #:
0865040672

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