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Haibo Liu, 52Columbus, OH

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Columbus, OH   

Raleigh, NC   

Acton, MA   

Johns Creek, GA   

Duluth, GA   

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Resumes

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Haibo Liu

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Haibo Liu

Location:
United States
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Haibo Liu

Publications & IP owners

Us Patents

Composition And Methods For Selective Degradation Of Engineered Proteins

US Patent:
2023009, Mar 30, 2023
Filed:
Aug 5, 2022
Appl. No.:
17/817777
Inventors:
- Summit NJ, US
Laura Akullian D'Agostino - Sudbury MA, US
Haibo Liu - Lexington MA, US
Veerabahu Shanmugasundaram - East Lyme CT, US
Brook Barajas - Seattle WA, US
Assignee:
Celgene Corporation - Summit NJ
International Classification:
C07K 14/47
C07K 14/725
Abstract:
The present disclosure relates to engineered polypeptides comprising degradation domains, compounds, compositions, and methods for their preparation and use as for degrading engineered proteins in cells.

Heteroaryl Compounds And Uses Thereof

US Patent:
2019037, Dec 12, 2019
Filed:
Jan 23, 2019
Appl. No.:
16/254838
Inventors:
- Pembroke, BM
- Paris, FR
Deqiang Niu - Lexington MA, US
Joseph John McDonald - Sudbury MA, US
Zhendong Zhu - Westborough MA, US
Haibo Liu - Lexington MA, US
Hormoz Mazdiyasni - Marlborough MA, US
Russell C. Petter - Stow MA, US
Juswinder Singh - Southborough MA, US
Matthieu Barrague - North Brunswick NJ, US
Alexandre Gross - Jersey City NJ, US
Mark Munson - Acton MA, US
International Classification:
C07D 239/80
C12N 9/96
C12N 9/12
A61K 51/04
A61K 49/00
A61K 31/519
A61K 31/517
C07D 519/00
A61K 47/54
C07D 239/84
C07D 471/04
C07D 487/04
C07D 495/04
Abstract:
The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.

Heteroaryl Compounds And Uses Thereof

US Patent:
2019021, Jul 18, 2019
Filed:
Aug 28, 2018
Appl. No.:
16/114380
Inventors:
- Pembroke, BM
- Paris, FR
Deqiang Niu - Lexington MA, US
Joseph John McDonald - Sudbury MA, US
Zhendong Zhu - Westborough MA, US
Haibo Liu - Lexington MA, US
Hormoz Mazdiyasni - Marlborough MA, US
Russell C. Petter - Stow MA, US
Juswinder Singh - Southborough MA, US
Matthieu Barrague - North Brunswick NJ, US
Alexandre Gross - Jersey City NJ, US
Mark Munson - Acton MA, US
Darren Harvey - Acton MA, US
Andrew Scholte - Somerville MA, US
Sachin Maniar - Arlington MA, US
International Classification:
C07D 487/04
C07D 239/94
C07D 239/80
C07D 471/04
C07D 519/00
Abstract:
The present invention relates to compounds useful as inhibitors of protein kinases, containing a cysteine residue in the ATP binding site. The invention further provides for pharmaceutically acceptable compositions comprising therapeutically effective amounts of one or more of the protein kinase inhibitor compounds and methods of using said compositions in the treatment of cancers and carcinomas.

Heteroaryl Compounds And Uses Thereof

US Patent:
2018002, Jan 25, 2018
Filed:
Jun 28, 2017
Appl. No.:
15/635954
Inventors:
- Pembroke, BM
- Paris, FR
Deqiang Niu - Lexington MA, US
Joseph John McDonald - Sudbury MA, US
Zhendong Zhu - Westborough MA, US
Haibo Liu - Lexington MA, US
Hormoz Mazdiyasni - Marlborough MA, US
Russell C. Petter - Stow MA, US
Juswinder Singh - Southborough MA, US
Matthieu Barrague - North Brunswick NJ, US
Alexandre Gross - Jersey City NJ, US
Mark Munson - Acton MA, US
International Classification:
C07D 239/80
C07D 519/00
A61K 31/519
C07D 487/04
C07D 471/04
A61K 49/00
A61K 31/517
C12N 9/12
C12N 9/96
C07D 239/84
A61K 51/04
C07D 495/04
A61K 47/54
Abstract:
The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.

Heteroaryl Compounds And Uses Thereof

US Patent:
2017026, Sep 21, 2017
Filed:
May 25, 2017
Appl. No.:
15/604786
Inventors:
- Pembroke, BM
- Paris, FR
Deqiang Niu - Lexington MA, US
Joseph John McDonald - Sudbury MA, US
Zhendong Zhu - Westborough MA, US
Haibo Liu - Lexington MA, US
Hormoz Mazdiyasni - Marlborough MA, US
Russell C. Petter - Stow MA, US
Juswinder Singh - Southborough MA, US
Matthieu Barrague - North Brunswick NJ, US
Alexandre Gross - Jersey City NJ, US
Mark Munson - Acton MA, US
Darren Harvey - Acton MA, US
Andrew Scholte - Somerville MA, US
Sachin Maniar - Arlington MA, US
International Classification:
C07D 487/04
C07D 471/04
C07D 519/00
C07D 239/80
Abstract:
The present invention relates to compounds useful as inhibitors of protein kinases, containing a cysteine residue in the ATP binding site. The invention further provides for pharmaceutically acceptable compositions comprising therapeutically effective amounts of one or more of the protein kinase inhibitor compounds and methods of using said compositions in the treatment of cancers and carcinomas.

Heteroaryl Compounds And Uses Thereof

US Patent:
2016022, Aug 4, 2016
Filed:
Apr 20, 2016
Appl. No.:
15/133755
Inventors:
- Cambridge MA, US
- Paris, FR
Deqiang Niu - Lexington MA, US
Joseph John McDonald - Sudbury MA, US
Zhendong Zhu - Westborough MA, US
Haibo Liu - Lexington MA, US
Hormoz Mazdiyasni - Marlborough MA, US
Russell C. Petter - Stow MA, US
Juswinder Singh - Southborough MA, US
Matthieu Barrague - North Brunswick NJ, US
Alexandre Gross - Jersey City NJ, US
Mark Munson - Acton MA, US
International Classification:
C07D 239/80
A61K 31/519
A61K 47/48
A61K 51/04
C12N 9/96
A61K 31/517
C07D 239/84
C07D 471/04
C12N 9/12
C07D 487/04
A61K 49/00
Abstract:
The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.

Heteroaryl Compounds And Uses Thereof

US Patent:
2016004, Feb 18, 2016
Filed:
Mar 14, 2014
Appl. No.:
14/776373
Inventors:
- Bedford MA, US
- Paris, FR
Deqiang Niu - Lexington MA, US
Joseph John McDonald - Sudbury MA, US
Zhendong Zhu - Westborough MA, US
Haibo Liu - Lexington MA, US
Hormoz Mazdiyasni - Marlborough MA, US
Russell C. Petter - Stow MA, US
Juswinder Singh - Southborough MA, US
Matthieu Barrague - North Brunswick NJ, US
Alexandre Gross - Jersey City NJ, US
Mark Munson - Acton MA, US
Darren Harvey - Acton MA, US
Andrew Scholte - Somerville MA, US
Sachin Maniar - Arlington MA, US
International Classification:
C07D 487/04
C07D 471/04
C07D 239/80
Abstract:
The present invention relates to compounds useful as inhibitors of protein kinases, containing a cysteine residue in the ATP binding site. The invention further provides for pharmaceutically acceptable compositions comprising therapeutically effective amounts of one or more of the protein kinase inhibitor compounds and methods of using said compositions in the treatment of cancers and carcinomas.

Heteroaryl Compounds And Uses Thereof

US Patent:
2014029, Oct 2, 2014
Filed:
Mar 14, 2014
Appl. No.:
14/212048
Inventors:
- Paris, FR
- Bedford MA, US
Deqiang Niu - Lexington MA, US
Joseph John McDonald - Sudbury MA, US
Zhendong Zhu - Westborough MA, US
Haibo Liu - Lexington MA, US
Hormoz Mazdiyasni - Marlborough MA, US
Russell C. Petter - Stow MA, US
Juswinder Singh - Ashland MA, US
Matthieu Barrague - North Brunswick NJ, US
Alexandre Gross - Jersey City NJ, US
Mark Munson - Acton MA, US
Assignee:
Sanofi - Paris
Celgene Avilomics Research, Inc. - Bedford MA
International Classification:
C07D 495/04
C07D 239/84
C07D 471/04
C07D 487/04
C07D 239/80
US Classification:
5142342, 544256, 5142621, 51425216, 544118, 544286, 51425217, 544279, 51426411, 544292, 5142664, 544238, 51425202, 435184
Abstract:
The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.

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