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Hsien Chang Cheng, 8529 Delmore Dr, Kendall Park, NJ 08824

Hsien Cheng Phones & Addresses

Kendall Park, NJ   

40 Hastings Rd, Belle Mead, NJ 08502    908-3599902   

Cincinnati, OH   

West Chester, OH   

Work

Position: Retired

Education

Degree: Graduate or professional degree

Mentions for Hsien Chang Cheng

Publications & IP owners

Us Patents

Antiallergic Compounds

US Patent:
5380731, Jan 10, 1995
Filed:
Aug 17, 1993
Appl. No.:
8/108786
Inventors:
Albert A. Carr - Cincinnati OH
John M. Kane - Cincinnati OH
Hsien C. Cheng - Cincinnati OH
Assignee:
Merrell Dow Pharmaceuticals Inc. - Cincinnati OH
International Classification:
A61K 31445
C07D40106
US Classification:
514322
Abstract:
The present invention is directed to a new class of piperidinyl benzimidazoles that are useful in the treatment of allergic disorders.

Lactamimides As Calcium Antagonists

US Patent:
5198433, Mar 30, 1993
Filed:
Jul 21, 1992
Appl. No.:
7/918350
Inventors:
Michael G. Palfreyman - Cincinnati OH
Norbert L. Wiech - Cincinnati OH
Hsien C. Cheng - Cincinnati OH
John M. Kane - Cincinnati OH
Assignee:
Merrell Dow Pharmaceuticals Inc. - Cincinnati OH
International Classification:
A61K 3133
A61K 3140
A61K 3144
A61K 3155
US Classification:
514212
Abstract:
Applicants have discovered that certain previously known lactamimide derivatives possess, as a class, valuable calcium channel blocking activity. By virtue of this calcium antagonism activity the compounds are antihypertensives and will have other activities associated with calcium antagonists.

Tetrahydro And Imidazoline Antisecretory Compounds

US Patent:
4260626, Apr 7, 1981
Filed:
Mar 26, 1979
Appl. No.:
6/023920
Inventors:
Albert A. Carr - Cincinnati OH
Hsien C. Cheng - Cincinnati OH
Stephen W. Horgan - Cincinnati OH
James K. Woodward - Cincinnati OH
Assignee:
Richardson-Merrell Inc. - Wilton CT
International Classification:
C07D23304
US Classification:
424273R
Abstract:
Novel antisecretory compounds of the formula: ##STR1## wherein R is ##STR2## and pharmaceutically acceptable salts, diasteriomers and individual optical isomers thereof.

Piperidinyl Thiacyclic Derivatives

US Patent:
5631268, May 20, 1997
Filed:
May 24, 1995
Appl. No.:
8/449034
Inventors:
Albert A. Carr - Cincinnati OH
John M. Kane - Cincinnati OH
George D. Maynard - Cincinnati OH
Hsien C. Cheng - Cincinnati OH
Mark W. Dudley - Somerville OH
Assignee:
Merrell Pharmaceuticals Inc. - Cincinnati OH
International Classification:
A61K 31445
C07D41702
US Classification:
514321
Abstract:
Piperidinyl thiacyclic derivatives of the formula ##STR1## wherein X, Y, R. sub. 1, R. sub. 2, R. sub. 3 and R. sub. 4 are defined in the specification, are useful in the treatment of allergic diseases and diseases responding to antagonism of 5HT. sub. 2 receptors. Pharmaceutical compositions and methods of treatment using these compounds are also disclosed.

Medicament Compositions Derived From Quinolizine And Quinolizinone And Methods Of Use Thereof

US Patent:
5011846, Apr 30, 1991
Filed:
May 16, 1990
Appl. No.:
7/527676
Inventors:
Maurice W. Gittos - Plobsheim, FR
Francis P. Miller - Loveland OH
Stephen M. Sorensen - Cincinnati OH
John R. Fozard - Hegenheim, FR
Paul Moser - Strasbourg, FR
Michael G. Palfreyman - Cincinnati OH
Hsien Cheng - Cincinnati OH
Assignee:
Merrell Dow Pharmaceuticals Inc. - Cincinnati OH
International Classification:
A61K47118
US Classification:
514294
Abstract:
The present invention is directed to the use of esters of hexahydro-8-hydroxy-2,6-methano-2H-quinolizin-3(4H)-one and hexahydro-8-hydroxy-2,6-methano-2H-quinolizines in the manufacture of a medicament for the treatment of anxiety, psychosis, glaucoma and for the stimulation of gastric motility.

Lactamimides As Calcium Antagonists

US Patent:
5158945, Oct 27, 1992
Filed:
Mar 11, 1992
Appl. No.:
7/850183
Inventors:
Michael G. Palfreyman - Cincinnati OH
Hsien C. Cheng - Cincinnati OH
Norbert L. Wiech - Cincinnati OH
John M. Kane - Cincinnati OH
Assignee:
Merrell Dow Pharmaceuticals Inc. - Cincinnati OH
International Classification:
A61K 3133
A61K 3144
A61K 3155
A61K 31445
US Classification:
514183
Abstract:
Applicants have discovered that certain previously known lactamimide derivatives possess, as a class, valuable calcium channel blocking activity. By virtue of this calcium antagonism activity the compounds are antihypertensives and will have other activities associated with calcium antagonists.

Piperidinyl Thiacyclic Derivatives

US Patent:
5371093, Dec 6, 1994
Filed:
Feb 24, 1994
Appl. No.:
8/201149
Inventors:
Albert A. Carr - Cincinnati OH
George D. Maynard - Cincinnati OH
John M. Kane - Cincinnati OH
Hsien C. Cheng - Cincinnati OH
Mark W. Dudley - Somerville OH
Assignee:
Merrell Dow Pharmaceuticals Inc. - Cincinnati OH
International Classification:
A61K 31445
C07D41702
US Classification:
514321
Abstract:
Piperidinyl thiacyclic derivatives ##STR1## wherein X, Y, R. sub. 1, R. sub. 2, R. sub. 3, and R. sub. 4 are defined in the specification. useful in the treatment of allergic diseases and diseases responding to antagonism of 5HT. sub. 2 receptors, pharmaceutical compositions and a methods of treatment using these compounds.

Lactamimides As Calcium Antagonists

US Patent:
5082837, Jan 21, 1992
Filed:
Nov 29, 1990
Appl. No.:
7/620226
Inventors:
Michael G. Palfreyman - Cincinnati OH
Norbert L. Wiech - Cincinnati OH
Hsien C. Cheng - Cincinnati OH
John M. Kane - Cincinnati OH
Assignee:
Merrell Dow Pharmaceuticals - Cincinnati OH
International Classification:
A01N 4300
A01N 4336
A01N 4340
A01N 4346
US Classification:
514183
Abstract:
Applicants have discovered that certain previously known lactamimide derivatives possess, as a class, valuable calcium channel blocking activity. By virtue of this calcium antagonism activity the compounds are antihypertensives and will have other activites associated with calcium antagonists.

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