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James Paul Lajiness, 395073 Abuela Dr, San Diego, CA 92124

Known as:
James P Lajiness
Related to:
Michael S Lajiness 71

James Lajiness Phones & Addresses

5073 Abuela Dr, San Diego, CA 92124   

Spring Valley, CA   

508 9Th Ave, Beech Grove, IN 46107   

Temperance, MI   

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James Paul Lajiness

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Work

Company: The scripps research institute Aug 2007 to Oct 2012 Position: Graduate student

Education

Degree: Doctorates, Doctor of Philosophy School / High School: Scripps Research 2007 to 2012 Specialities: Philosophy, Organic Chemistry

Skills

Medicinal Chemistry • Organic Chemistry • Organic Synthesis • Lc Ms • Chemistry • Nmr • Drug Discovery • Mass Spectrometry • Biochemistry • Hplc • Microsoft Office • Public Speaking

Languages

English

Industries

Chemicals
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Mentions for James Paul Lajiness

James Lajiness resumes & CV records

Resumes

James Lajiness Photo 13

Investigator Iii

Location:
5073 Abuela Dr, San Diego, CA 92124
Industry:
Chemicals
Work:
The Scripps Research Institute Aug 2007 - Oct 2012
Graduate Student Gnf Aug 2007 - Oct 2012
Investigator Iii
Education:
Scripps Research 2007 - 2012
Doctorates, Doctor of Philosophy, Philosophy, Organic Chemistry Hope College 2003 - 2007
Bachelors, Bachelor of Science, Chemistry
Skills:
Medicinal Chemistry, Organic Chemistry, Organic Synthesis, Lc Ms, Chemistry, Nmr, Drug Discovery, Mass Spectrometry, Biochemistry, Hplc, Microsoft Office, Public Speaking
Languages:
English

Publications & IP owners

Us Patents

Compounds And Compositions For Inducing Chondrogenesis

US Patent:
2021034, Nov 11, 2021
Filed:
Jul 6, 2021
Appl. No.:
17/368537
Inventors:
- Basel, CH
Jiqing JIANG - San Diego CA, US
James Paul LAJINESS - San Diego CA, US
Bao NGUYEN - San Diego CA, US
Hank Michael James Petrassi - Fallbrook CA, US
International Classification:
C07D 493/08
A61K 9/00
A61K 31/343
Abstract:
The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof;

Compounds And Compositions For Inducing Chondrogenesis

US Patent:
2021007, Mar 18, 2021
Filed:
Jun 7, 2018
Appl. No.:
16/620407
Inventors:
- Basel, CH
Jiqing JIANG - San Diego CA, US
James Paul LAJINESS - San Diego CA, US
Bao NGUYEN - San Diego CA, US
Hank Michael James Petrassi - San Diego CA, US
International Classification:
C07D 493/08
A61K 31/343
A61K 9/00
Abstract:
The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; (I) or a pharmaceutically acceptable salt, tautomer, or stereoisomer thereof, wherein the variables are as defined herein. The present invention further provides pharmaceutical compositions comprising such compounds; and methods of using such compounds for treating joint damage or injury in a mammal, for inducing hyaline cartilage production or for inducing differentiation of chondrogenic progenitor cells into mature chondrocytes.

Compounds And Compositions For Inducing Chondrogenesis

US Patent:
2020023, Jul 30, 2020
Filed:
Apr 14, 2020
Appl. No.:
16/848568
Inventors:
- Basel, CH
James Paul Lajiness - San Diego CA, US
Srinivasa Reddy Natala - San Diego CA, US
Bao Nguyen - San Diego CA, US
Hank Michael James Petrassi - San Diego CA, US
Zhicheng Wang - San Diego CA, US
International Classification:
A61K 31/443
C12N 5/077
A61K 31/444
A61L 27/54
A61K 31/34
A61K 31/4439
A61K 31/4433
C07D 491/18
A61K 31/5377
A61K 31/506
A61K 31/4245
A61K 31/351
A61K 31/416
A61K 31/4525
A61K 31/4155
C07D 493/08
A61K 45/06
A61K 31/4545
A61K 31/497
Abstract:
The present invention provides compounds of formula I:or a pharmaceutically acceptable salt, tautomer, or stereoisomer thereof, wherein the variables are as defined herein. The present invention further provides pharmaceutical compositions comprising such compounds, and methods of using such compounds for treatment of joint damage or joint injury in a mammal, and for inducing differentiation of mesenchymal stem cells into chondrocytes.

Compounds And Compositions For Inducing Chondrogenesis

US Patent:
2019031, Oct 17, 2019
Filed:
Jun 21, 2019
Appl. No.:
16/448547
Inventors:
- Basel, CH
James Paul Lajiness - San Diego CA, US
Srinivasa Reddy Natala - San Diego CA, US
Bao Nguyen - San Diego CA, US
Hank Michael James Petrassi - San Diego CA, US
Zhicheng Wang - San Diego CA, US
International Classification:
A61K 31/443
A61K 45/06
C07D 491/18
A61K 31/497
A61K 31/4525
A61K 31/4545
A61K 31/351
A61K 31/5377
A61K 31/4439
A61K 31/34
A61K 31/506
A61K 31/4155
A61K 31/4245
A61K 31/444
C07D 493/08
A61K 31/4433
A61K 31/416
A61L 27/54
C12N 5/077
Abstract:
The present invention provides compounds of formula I:or a pharmaceutically acceptable salt, tautomer, or stereoisomer thereof, wherein the variables are as defined herein. The present invention further provides pharmaceutical compositions comprising such compounds, and methods of using such compounds for treatment of joint damage or joint injury in a mammal, and for inducing differentiation of mesenchymal stem cells into chondrocytes.

Aza-Indazole Compounds For Use In Tendon And/Or Ligament Injuries

US Patent:
2019030, Oct 3, 2019
Filed:
Sep 21, 2017
Appl. No.:
16/335496
Inventors:
- Basel, CH
Andreas FISCH - Basel, CH
James Paul LAJINESS - San Diego CA, US
Rainer MACHAUER - Freiburg, DE
Swapnil MALEKAR - Emeryville CA, US
Hank Michael James PETRASSI - San Diego CA, US
Farshad RAMAZANI - Basel, CH
Anne-Catherine REMOND - Bartenheim, FR
Thomas ULLRICH - Bottmingen, CH
Peggy USSELMANN - Wahlbach, FR
Eric VANGREVELINGHE - Saint-Louis, FR
International Classification:
C07D 471/04
A61K 9/00
A61K 9/50
A61P 21/00
A61K 31/437
A61K 31/538
A61K 31/496
Abstract:
The present invention provides a compound of formula (I) in free form or in pharmaceutically acceptable salt form, a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

Indazole Compounds For Use In Tendon And/Or Ligament Injuries

US Patent:
2018008, Mar 29, 2018
Filed:
Sep 21, 2017
Appl. No.:
15/711984
Inventors:
- Basel, CH
Andreas FISCH - Basel, CH
James Paul LAJINESS - San Diego CA, US
Rainer MACHAUER - Freiburg, DE
Swapnil MALEKAR - Emeryville CA, US
Hank Michael James PETRASSI - San Diego CA, US
Farshad RAMAZANI - Basel, CH
Anne-Catherine REMOND - Bartenheim, FR
Thomas ULLRICH - Bottmingen, CH
Peggy USSELMANN - WAHLBACH, FR
Eric VANGREVELINGHE - Saint-Louis, FR
International Classification:
C07D 231/56
A61K 9/16
A61K 9/00
C07D 403/12
A61K 31/416
C07D 401/12
A61K 31/454
C07D 405/12
Abstract:
The present invention provides a compound of formula (I) in free form or in pharmaceutically acceptable salt forma method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

Compounds And Compositions For Inducing Chondrogenesis

US Patent:
2017023, Aug 24, 2017
Filed:
May 5, 2017
Appl. No.:
15/587652
Inventors:
- Basel, CH
James Paul Lajiness - San Diego CA, US
Srinivasa Reddy Natala - San Diego CA, US
Bao Nguyen - San Diego CA, US
Hank Michael James Petrassi - San Diego CA, US
Zhicheng Wang - San Diego CA, US
International Classification:
A61K 31/443
A61K 31/4155
A61K 31/506
A61K 31/34
A61K 31/4439
A61K 31/5377
A61K 31/416
A61K 31/351
A61K 31/4545
A61K 31/4525
A61K 31/497
A61K 31/4433
A61K 31/444
C12N 5/077
A61K 45/06
A61L 27/54
A61K 31/4245
Abstract:
The present invention provides compounds of formula I:or a pharmaceutically acceptable salt, tautomer, or stereoisomer thereof, wherein the variables are as defined herein. The present invention further provides pharmaceutical compositions comprising such compounds, and methods of using such compounds for treatment of joint damage or joint injury in a mammal, and for inducing differentiation of mesenchymal stem cells into chondrocytes.

Compounds And Compositions For Inducing Chondrogenesis

US Patent:
2015032, Nov 19, 2015
Filed:
May 12, 2015
Appl. No.:
14/709852
Inventors:
Ha-Soon CHOI - San Diego CA, US
James Paul LAJINESS - San Diego CA, US
Srinivasa Reddy NATALA - San Diego CA, US
Bao NGUYEN - San Diego CA, US
Hank Michael James PETRASSI - Cardiff CA, US
Zhicheng WANG - San Diego CA, US
Assignee:
NOVARTIS AG - Basel
International Classification:
C07D 493/08
A61K 31/4245
A61K 31/4155
A61K 31/506
A61K 31/34
C07D 491/18
A61K 31/4439
A61K 31/5377
A61K 31/351
A61K 31/4545
A61K 31/4525
A61K 31/497
A61K 31/444
A61K 45/06
A61K 31/443
Abstract:
The present invention provides compounds of formula I:or a pharmaceutically acceptable salt, tautomer, or stereoisomer thereof, wherein the variables are as defined herein. The present invention further provides pharmaceutical compositions comprising such compounds, and methods of using such compounds for treatment of joint damage or joint injury in a mammal, and for inducing differentiation of mesenchymal stem cells into chondrocytes.

Possible Relatives

Jessica P Lajiness  Michael T Lajiness  William C Lajiness  James V Johnson  James C Stamps  James E Stanage  James I Stanaland  James E Stanard  James B Stanaway  James P Stanberry 

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