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Laxma R Kolla, 629 Stobbe Ln, Princeton Junction, NJ 08550

Known as:
Laxman R Kolla Laxma Kolua Kolla R Laxma A Kolla
Related to:
Sudha S Kolla

Laxma Kolla Phones & Addresses

Princeton Junction, NJ   

2 Penn Pl, Rocky Hill, CT 06067    860-5639175   

2 Skiff St, Hamden, CT 06514    203-2308163   

North Brunswick, NJ   

San Diego, CA   

Plainsboro, NJ   

2 Skiff St APT 205, Hamden, CT 06514    203-5004542   

Work

Position: Machine Operators, Assemblers, and Inspectors Occupations

Education

Degree: High school graduate or higher
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Mentions for Laxma R Kolla

Publications & IP owners

Us Patents

Ppar- Agonists As Agents For The Treatment Of Type Ii Diabetes

US Patent:
6713514, Mar 30, 2004
Filed:
Apr 18, 2000
Appl. No.:
09/552477
Inventors:
Hartmuth C. Kolb - East Windsor NJ
Gerard McGeehan - Chester Springs PA
Zhi-Cai Shi - North Brunswick NJ
Laxma Reddy Kolla - North Brunswick NJ
Cullen Cavallaro - Allentown NJ
Assignee:
Lexicon Pharmaceuticals, Inc. - Princeton NJ
International Classification:
A61K 31195
US Classification:
514563, 514538, 562426, 562431, 562445
Abstract:
N-(substituted)carbamoylaryl- and heteroaryl substituted aminopropanoic and butanoic acid compounds which are highly selective agonists for the PPAR- receptor or prodrugs of agonists for the PPAR- receptor, and are useful in the treatment of Type II diabetes (NIDDM). Specifically disclosed are compounds of the formula: or the pharmaceutically acceptable non-toxic salts thereof wherein: Z is aryl or heteroaryl; n and m are 0, 1 or 2; A is a carboxylic acid or ester; or A is where D, F and G are hydrogen, (un)substituted amino, (un)substituted alkoxy, methylene or an (un)substituted sulfide; R is oxo, hydrogen, hydroxy, lower alkyl, lower alkoxy, cycloalkyl, keto, acyl, or sulfonyl; Y is hydrogen, (un)substituted amino, (un)substituted alkoxy, methylene, an (un)substituted sulfide, (un)substituted sulfonyl or an (un)substituted sulfoxide; and R , R and R are hydrogen, lower alkyl, lower alkoxy, cycloalkyl, keto, acyl, or sulfonyl; or R and R together form a ring.

Triazolopyridine 11-Beta Hydroxysteroid Dehydrogenase Type I Inhibitors

US Patent:
8119658, Feb 21, 2012
Filed:
Sep 9, 2008
Appl. No.:
12/206801
Inventors:
Jun Li - Princeton NJ, US
Jeffrey A. Robl - Newtown PA, US
James J. Li - Pennington NJ, US
Lawrence J. Kennedy - Titusville NJ, US
Haixia Wang - Princeton NJ, US
Jie Jack Li - Killingworth CT, US
Xinhua Qian - Flemington NJ, US
Rajendra P. Deshpande - Hillsborough NJ, US
Laxma R. Kolla - Princeton Junction NJ, US
Reginald O. Cann - Princeton Junction NJ, US
Chenkou Wei - Princeton Junction NJ, US
Michael Galella - Kendall Park NJ, US
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
A61K 31/437
C07D 471/04
A61P 3/04
A61P 3/10
A61P 9/12
A61P 3/00
US Classification:
514303, 546119
Abstract:
Novel compounds are provided which are 11-beta-hydroxysteroid dehydrogenase type I inhibitors. 11-beta-hydroxysteroid dehydrogenase type I inhibitors are useful in treating, preventing, or slowing the progression of diseases requiring 11-beta-hydroxysteroid dehydrogenase type I inhibitor therapy. These novel compounds of formula I:.

Process For Water Soluble Azole Compounds

US Patent:
2002006, May 23, 2002
Filed:
Oct 16, 2001
Appl. No.:
09/982199
Inventors:
Chung-Pin Chen - Madison CT, US
Timothy Connolly - Meriden CT, US
Laxma Kolla - Rocky Hill CT, US
John Matiskella - Wallingford CT, US
Richard Mueller - Ringoes NJ, US
Yadagiri Pendri - South Glastonbury CT, US
Dejah Petsch - Mansfield Center CT, US
International Classification:
C07F009/6539
C07F009/6518
US Classification:
548/117000, 548/118000
Abstract:
An improved process is provided for preparing water-soluble prodrugs of triazole antifungal compounds containing a secondary or tertiary hydroxyl group. More particularly, the improved process is directed toward preparation of water-soluble triazole antifungal compounds are provided having the general formula wherein A is the non-hydroxy portion of a triazole antifungal compound of the type containing a secondary or tertiary hydroxyl group and R and Rare as defined in the specification.

Novel Ppar-Gamma Agonists As Agents For The Treatment Of Type Ii Diabetes

US Patent:
2004017, Sep 2, 2004
Filed:
Mar 10, 2004
Appl. No.:
10/797458
Inventors:
Hartmuth Kolb - East Windsor NJ, US
Gerard McGeehan - Chester Springs PA, US
Zhi-Cai Shi - North Brunswick NJ, US
Laxma Kolla - North Brunswick NJ, US
Cullen Cavallaro - Allentown NJ, US
International Classification:
C07D213/55
A61K031/44
A61K031/40
US Classification:
514/357000, 514/408000, 514/567000, 546/335000, 548/571000, 562/442000, 562/430000
Abstract:
Disclosed are compounds of the formula: or the pharmaceutically acceptable non-toxic salts thereof wherein: Z is aryl or heteroaryl; n and m are 0, or A is a carboxylic acid or ester; or A is where D, F and G are hydrogen, (un)substituted amino, (un)substituted alkoxy, methylene or an (un)substituted sulfide; X is N, O, CH, S, SO or SO; Ris oxo, hydrogen, hydroxy, lower alkyl, lower alkoxy, cycloalkyl, keto, acyl, or sulfonyl; Y is hydrogen, (un)substituted amino, (un)substituted alkoxy, methylene, an (un)substituted sulfide, (un)substituted sulfonyl or an (un)substituted sulfoxide; and R, Rand Rare hydrogen, lower alkyl, lower alkoxy, cycloalkyl, keto, acyl, or sulfonyl; or Rand Rtogether form a ring. These [N-(substituted)carbamoylaryl- and heteroaryl aminopropanoic and butanoic acid compounds are highly selective agonists for the PPAR- receptor or prodrugs of agonists for the PPAR- receptor. Thus these compounds are useful in the treatment of Type II diabetes (NIDDM).

Hmg-Coa Reductase Inhibitors And Method

US Patent:
2005017, Aug 4, 2005
Filed:
Nov 15, 2004
Appl. No.:
10/989138
Inventors:
Stephen O'Connor - Lambertville NJ, US
Jeffrey Robl - Newtown PA, US
Saleem Ahmad - Wall NJ, US
Sharon Bisaha - Lambertville NJ, US
Natesan Murugesan - Princeton Juction NJ, US
Khehyong Ngu - Pennington NJ, US
Yan Shi - Flourtown PA, US
Philip Stein - Pennington NJ, US
Nachimuthu Soundararajan - Kendall Park NJ, US
Kenneth Natalie - Flemington NJ, US
Laxma Kolla - Plainsboro NJ, US
Justin Sausker - Middletown CT, US
Sandra Quinlan - West Simsbury CT, US
Junying Fan - Monmouth Junction NJ, US
Dejah Petsch - Ashford CT, US
Zhenrong Guo - East Brunswick NJ, US
International Classification:
A61K031/4745
C07D471/02
US Classification:
514300000, 546122000
Abstract:
Compounds are provided having the following structure and pharmaceutically acceptable salts thereof, wherein R, R, R, R, U, V, W, Y, and n are as defined above, which compounds are HMG CoA reductase inhibitors and thus are active in inhibiting cholesterol biosynthesis, modulating blood serum lipids, for example, lowering LDL cholesterol and/or increasing HDL cholesterol, and treating hyperlipidemia, dyslipidemia, hypercholesterolemia, hypertriglyceridemia and atherosclerosis as well as Alzheimer's disease and osteoporosis and may be employed as hormone replacement therapy. A method for treating the above diseases employing the above compounds is also provided.

Cephalosporin Compositions And Methods Of Manufacture

US Patent:
2015011, Apr 23, 2015
Filed:
Oct 22, 2014
Appl. No.:
14/521421
Inventors:
- Lexington MA, US
Pradip M. Pathare - Lexington MA, US
Laxma Kolla - Princeton Jct. NJ, US
Adrien F. Soret - Brighton MA, US
International Classification:
C07D 501/59
C07D 501/34
C07D 501/22
C07D 501/57
A61K 31/41
A61K 31/546
A61K 31/433
A61K 31/675
A61K 31/426
C07D 501/56
C07D 501/36
US Classification:
514 80, 540217, 514202, 514 92
Abstract:
Provided herein is a method for the synthesis of cephalosporin antibiotic compounds comprising the conversion of a protected 7-amino group into a 7-carboxamide moiety in a single step.

Cephalosporin Compositions And Methods Of Manufacture

US Patent:
2014027, Sep 18, 2014
Filed:
Mar 14, 2014
Appl. No.:
14/211526
Inventors:
- Lexington MA, US
Pradip M. Pathare - Lexington MA, US
Laxma Kolla - Princeton Jct. NJ, US
Adrien F. Soret - Brighton MA, US
International Classification:
C07D 501/06
A61K 31/546
A61K 31/545
A61K 31/433
A61K 31/426
A61K 31/41
C07F 9/6561
C07D 501/04
US Classification:
514 80, 514202, 514206, 514361, 540215, 540222, 540225, 540230
Abstract:
Provided herein is a method for the synthesis of cephalosporin antibiotic compounds comprising the conversion of a protected 7-amino group into a 7-carboxamide moiety in a single step.

Cephalosporin Compositions And Methods Of Manufacture

US Patent:
2014027, Sep 18, 2014
Filed:
Mar 14, 2014
Appl. No.:
14/211465
Inventors:
- Lexington MA, US
Pradip M. Pathare - Lexington MA, US
Laxma Kolla - Princeton Jct. NJ, US
Adrien F. Soret - Brighton MA, US
International Classification:
C07D 501/06
A61K 31/433
A61K 31/546
US Classification:
514202, 540222, 548128
Abstract:
Provided herein is a method for the synthesis of cephalosporin antibiotic compounds comprising the conversion of a protected 7-amino group into a 7-carboxamide moiety in a single step.

Possible Relatives

Krishna S Kolla  Srinivas Kolla  Vivekananda R Kolla  Laxma R Katta 

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