Theodore J Stanley, 53Missouri City, TX

6488959, Dec 3, 2002

May 24, 2001

09/864472

Theodore Stanley - Salt Lake City UT
Wade Hull - Taylorsville UT
Larry Rigby - Salt Lake City UT
Jie Zhang - Salt Lake City UT

Zars, Inc. - Salt Lake City UT

A61F 1300

424449, 424448, 424447, 604 20

The present invention relates to a transdermal drug delivery system comprising a dermal drug delivery patch and a heating element compartment securable to the dermal drug delivery patch. A freely transferrable heating element is securable within the heating element compartment. A drug can be administered transdermally using the present invention by placing the dermal drug delivery patch upon a patients skin at an administration site. A heating element compartment is secured to the dermal drug delivery patch and a freely transferrable heating element is placed within the heating element compartment. The heating element provides controlled heat to the dermal drug patch and the patients skin and thereby improves dermal drug administration.

6955819, Oct 18, 2005

Feb 28, 2001

09/796250

Jie Zhang - Salt Lake City UT, US
Wade Hull - Taylorsville UT, US
Larry Rigby - Salt Lake City UT, US
Theodore Stanley - Salt Lake City UT, US

Zars, Inc. - Salt Lake City UT

A61K009/70
A61F013/00

424449, 424401, 424443, 424447

The present invention is directed toward an apparatus to rapidly deliver a drug to a patient The invention comprises a drug beneath a patient's skin in a drug depot site. A heating component is placed near the drug depot site and generates heat in and near the drug depot site. A control component connected to the heating component is used to control the magnitude and duration of heat generated by the heating component.

2007016, Jul 19, 2007

Mar 13, 2007

11/685394

Daniel Vezina - Park City UT, US
Theodore Stanley - Salt Lake City UT, US

University of Utah Research Foundation - Salt Lake City UT

G06F 17/30

707003000

Techniques for providing expert instruction in interpreting outputs of a test instrument to a student who is at a location remote from the expert. The student makes outputs from the test instrument and an interpretation of the outputs available to an expert via a network and receives a commented and graded response in return. The outputs, the interpretation, and the response may be made available in real time or in non-real time. In the non-real-time embodiment, the student makes his interpretation by selecting from menus of possible observations, the expert does the same, and the two interpretations are automatically compared to produce the comments and grade for the response. One application of the invention is teaching echocardiography.

5291887, Mar 8, 1994

Jun 2, 1992

7/892287

Theodore H. Stanley - Salt Lake City UT
Jie Zhang - West Valley UT

Anesta Corporation - Salt Lake City UT

A61B 500

128637

The present invention is directed to novel methods and apparatus for noninvasively collecting substances through mucosal tissues. The concentration of a substance in blood is monitored noninvasively by correlation with the amount of the substance which permeates a mucosal membrane into a substance receiving medium over a specified time period. The substance receiving medium may include an substance permeation enhancer capable of increasing the substance permeability across the mucosal membrane. The substance receiving medium is positioned against the mucosal membrane. After sufficient time delay, the substance receiving medium is removed and analyzed for the concentration of a substance to be measured using known analytical techniques. The apparatus within the scope of the present invention includes means for supporting the substance receiving medium. The means for supporting the receiving medium provides an added benefit of isolating the substance receiving medium from contamination sources.

4671953, Jun 9, 1987

May 1, 1985

6/729301

Theodore H. Stanley - Salt Lake City UT
Brian Haque - West Valley City UT

University of Utah Research Foundation - Salt Lake City UT

A61J 308
A61K 920
A61K 31445

424440

The present invention is directed to methods and compositions for noninvasively administering drugs having a sedative, analgesic, or anesthetic effect. A drug capable of absorption through mucosal tissues in incorporated into a candy matrix, which is then advantageously formed into a lollipop. A patient is put at ease when given the lollipop, and the drug rapidly enters the patient's bloodstream as the lollipop is sucked. When sedating or anesthetizing the patient, the physician can observe the patient's condition and remove the lollipop when it has had a desired effect on the patient. Alternatively, the physican can alter placement of the lollipop to slow the rate of the drug release for absorption into the patient's system. An analgesic-containing lollipop can be self-administrated by a patient in response to his own subjective experience of pain and to the patient's susceptibility to the particular drug utilized.

5855908, Jan 5, 1999

Nov 15, 1994

8/339655

Theodore H. Stanley - Salt Lake City UT
Brian Hague - West Valley City UT

University of Utah Research Foundation - Lake City UT

A61K 968

424440

Compositions and methods of manufacture for producing a medicament composition capable of absorption through the mucosal tissues of the mouth, pharynx, and esophagus. The present invention relates to such compositions and methods which are useful in administering lipophilic and nonlipophilic drugs in a dose-to-effect manner such that sufficient drug is administered to produce precisely a desired effect. The invention also relates to manufacturing techniques that enable therapeutic agents to be incorporated into nondissolvable drug containment matrixes which are capable of releasing the drug within a patient's mouth. An appliance or holder is preferably attached to the drug containment matrix. Employing the present invention the drug may be introduced into the patient's bloodstream almost as fast as through injection, and much faster than using the oral administration route, while avoiding the negative aspects of both of these methods. The nondissolvable drug containment matrix may include permeation enhancers to increase the drug absorption by the mucosal tissues of the mouth.

5484602, Jan 16, 1996

Jan 20, 1995

8/376642

Theodore H. Stanley - Salt Lake City UT
Brian Hague - West Valley City UT

University of Utah Research Foundation - Salt Lake City UT

A61K 968

424440

The present invention is directed to methods and compositions for noninvasively administering drugs in a dose-to-effect manner to produce a cardiovascular or renal vascular activity. A cardiovascular or renal vascular drug, which is capable of absorption through mucosal tissues of the mouth, pharnyx, and esophagus is incorporated into a matrix which is in the form of a lollipop. A patient is put at ease when given the lollipop, and the drug rapidly enters the patient's bloodstream as the lollipop is sucked. When treating the patient, the physician can observe the patient's condition and remove the lollipop when it has had a desired effect on the patient. A lollipop into which a cardiovascular or renal vascular drug has been dispersed is particularly useful for achieving rapid vasodilating, calcium channel blocking, beta-blocking, seritonin receptor blocking, angina blocking, antihypertensive, and cardiac stimulating effects and for controlling urine output.

5824334, Oct 20, 1998

Apr 19, 1996

8/636828

Theodore H. Stanley - Salt Lake City UT
Brian I. Hague - West Valley City UT

University of Utah Research Foundation - Salt Lake City UT

A61K 968

424440

The present invention relates generally to a cigarette substitute for administering a dose of nicotine. More specifically, the present invention is directed to a nicotine-containing dosage-form comprising a holder member which may be used as part of an effective smoking cessation program or in situations where smoking is undesirable or not permitted. The dosage form is configured as a dosage form having a nicotine-containing composition attached to a holder member. Nicotine is released from the dosage form and absorbed through the intra-oral mucosal surfaces as the nicotine-containing composition releases nicotine within a user's mouth. The holder member facilitates insertion and removal of the dosage form into and out of a user's mouth. The user can selectively insert and remove the dosage form as desired to selectively control the release of nicotine. In addition, the user can insert and remove the dosage form in a manner which meets the user's psychological need or desire for ritualistic oral stimulation similar to cigarette smoking.