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Xinyi C Chen, 541812 Granemore St, Las Vegas, NV 89135

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Las Vegas, NV   

Temecula, CA   

23301 Park Colombo, Calabasas, CA 91302    818-5191573   

292 Via Monterey, Newbury Park, CA 91320   

Thousand Oaks, CA   

3807 Steeplechase Dr, Carmel, IN 46032   

Los Angeles, CA   

Newark, CA   

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Us Patents

Dual Function In Vitro Target Binding Assay For The Detection Of Neutralizing Antibodies Against Target Antibodies

US Patent:
2014007, Mar 13, 2014
Filed:
Aug 10, 2011
Appl. No.:
13/816442
Inventors:
Xinyi Cynthia Chen - Calabasas CA, US
Shalini Gupta - Newbury Park CA, US
Francesca Civoli - Newbury Park CA, US
Assignee:
AMGEN INC. - Thousand Oaks CA
International Classification:
G01N 33/577
US Classification:
435 721, 436501, 435 75
Abstract:
An in vitro assay method is disclosed. This non-cell-based dual function target binding assay is useful for detecting both an IgG target antibody, such as a biologic drug, in a biological sample (e.g., a serum sample) and the presence of neutralizing antibodies (NAb) against the IgG target antibody.

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